biostackdev's profile picture. Building @stackvity | digital twin for longevity

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@biostackdev

Building @stackvity | digital twin for longevity

Angepinnt

If you had an idea that was going to outrage society, would you keep it to yourself?


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Discovery and protein language model-guided design of hyperactive transposases go.nature.com/4gXLGEw

NatureBiotech's tweet image. Discovery and protein language model-guided design of hyperactive transposases go.nature.com/4gXLGEw

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Senescence-resistant human mesenchymal progenitor cells counter aging in primates 🐒 👉 “This study provides initial evidence that genetically modified human mesenchymal progenitors can slow primate aging” cell.com/cell/fulltext/…

agingdoc1's tweet image. Senescence-resistant human mesenchymal progenitor cells counter aging in primates 🐒

👉 “This study provides initial evidence that genetically modified human mesenchymal progenitors can slow primate aging”

cell.com/cell/fulltext/…

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Scaling DNA synthesis with a microchip-based massively parallel synthesis system go.nature.com/3VKimYk

NatureBiotech's tweet image. Scaling DNA synthesis with a microchip-based massively parallel synthesis system go.nature.com/3VKimYk

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Cardiac ageing: from hallmarks to therapeutic opportunities academic.oup.com/cardiovascres/…

agingdoc1's tweet image. Cardiac ageing: from hallmarks to therapeutic opportunities

academic.oup.com/cardiovascres/…

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Mitochondrial integrity stands out as a major gatekeeper for the control of genetic, metabolic, and inflammatory homeostasis;

Madam_Mito's tweet image. Mitochondrial integrity stands out as a major gatekeeper for the control of genetic, metabolic, and inflammatory homeostasis;

Inflammation and mitophagy are mitochondrial checkpoints to aging | Nature Communications nature.com/articles/s4146…



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Integrative physiology of skeletal muscle for maintaining cognitive health physoc.onlinelibrary.wiley.com/doi/10.1113/JP…

ChristophBurch's tweet image. Integrative physiology of skeletal muscle for maintaining cognitive health
physoc.onlinelibrary.wiley.com/doi/10.1113/JP…

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Sarcopenia: age-related loss of skeletal muscle mass & function👇🏼 >reduced regenerative capacity >imbalance in protein turnover >alteration of muscle’s fat composition >increased reactive oxygen species >mitochondrial dysfunction >increased inflammation link.springer.com/article/10.100…

Omid_HopeUni's tweet image. Sarcopenia: age-related loss of skeletal muscle mass & function👇🏼

>reduced regenerative capacity
>imbalance in protein turnover
>alteration of muscle’s fat composition
>increased reactive oxygen species
>mitochondrial dysfunction 
>increased inflammation

link.springer.com/article/10.100…

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Dynamic fibroblast–immune interactions shape recovery after brain injury🔥 nature.com/articles/s4158…


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I'm excited to finally share this work led by @FarahJaberH : Inactivation of Histone Chaperone HIRA Unmasks a Link Between Normal Embryonic Development of Melanoblasts and Maintenance of Adult Melanocyte Stem Cells. Published in Aging Cell. doi.org/10.1111/acel.7…

AdamsBioAging's tweet image. I'm excited to finally share this work led by @FarahJaberH :  Inactivation of Histone Chaperone HIRA Unmasks a Link Between Normal Embryonic Development of Melanoblasts and Maintenance of Adult Melanocyte Stem Cells. Published in Aging Cell. doi.org/10.1111/acel.7…

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NEW content online! Recent advances in therapeutic cancer vaccines bit.ly/4k1eXyK

NatureRevCancer's tweet image. NEW content online! Recent advances in therapeutic cancer vaccines bit.ly/4k1eXyK

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Anticoagulants – Summary. manualofmedicine.com

drsthanus's tweet image. Anticoagulants – Summary.

manualofmedicine.com

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If you’re wondering what epigenetic reprogramming is, it’s the turning on of a subset of embryonic genes (Sox2, Klf4, Oct4) that results in a reset of gene expression so old tissues regain their identity and hence function and heal like they are young again


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What if the path to slowing aging wasn’t a drug, but replacing worn out parts? Our new paper out today in @NatureAging shows how this could one day work. We map a unified framework—from scaffolds & bioprinted tissues to pacemakers, xenotransplants & brain machine interfaces—for…

Sierra_Lore_'s tweet image. What if the path to slowing aging wasn’t a drug, but replacing worn out parts? 

Our new paper out today in @NatureAging shows how this could one day work. We map a unified framework—from scaffolds & bioprinted tissues to pacemakers, xenotransplants & brain machine interfaces—for…

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Longevity company Unity Biotechnology provides new evidence their drug candidate clears old senescent cells in the retina providing lasting improvements in vision 👁️👁️ Longevity science is coming of age 👏

davidasinclair's tweet image. Longevity company Unity Biotechnology provides new evidence their drug candidate clears old senescent cells in the retina providing lasting improvements in vision 👁️👁️ Longevity science is coming of age 👏

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A baby has been born after being conceived via IVF performed by a machine, with a medical professional merely overseeing the process newscientist.com/article/247589…


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Anesthesia gold

OGdukeneurosurg's tweet image. Anesthesia gold

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Hormones

OGdukeneurosurg's tweet image. Hormones

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Arterial Tree of Life

OGdukeneurosurg's tweet image. Arterial Tree of Life

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Amazing spinal cord development by Elizabeth Haynes & Jiaye He.


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