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If you had an idea that was going to outrage society, would you keep it to yourself?
The Lipid Brain Atlas is out now! If you think lipids are boring and membranes are all the same, prepare to be surprised. Led by Luca Fusar Bassini with Gioele La Manno's lab, we mapped membrane lipids in the mouse brain at high resolution. biorxiv.org/cgi/content/sh…
Discovery and protein language model-guided design of hyperactive transposases go.nature.com/4gXLGEw
Senescence-resistant human mesenchymal progenitor cells counter aging in primates 🐒 👉 “This study provides initial evidence that genetically modified human mesenchymal progenitors can slow primate aging” cell.com/cell/fulltext/…
Scaling DNA synthesis with a microchip-based massively parallel synthesis system go.nature.com/3VKimYk
Cardiac ageing: from hallmarks to therapeutic opportunities academic.oup.com/cardiovascres/…
Mitochondrial integrity stands out as a major gatekeeper for the control of genetic, metabolic, and inflammatory homeostasis;
Inflammation and mitophagy are mitochondrial checkpoints to aging | Nature Communications nature.com/articles/s4146…
Integrative physiology of skeletal muscle for maintaining cognitive health physoc.onlinelibrary.wiley.com/doi/10.1113/JP…
Sarcopenia: age-related loss of skeletal muscle mass & function👇🏼 >reduced regenerative capacity >imbalance in protein turnover >alteration of muscle’s fat composition >increased reactive oxygen species >mitochondrial dysfunction >increased inflammation link.springer.com/article/10.100…
Dynamic fibroblast–immune interactions shape recovery after brain injury🔥 nature.com/articles/s4158…
I'm excited to finally share this work led by @FarahJaberH : Inactivation of Histone Chaperone HIRA Unmasks a Link Between Normal Embryonic Development of Melanoblasts and Maintenance of Adult Melanocyte Stem Cells. Published in Aging Cell. doi.org/10.1111/acel.7…
NEW content online! Recent advances in therapeutic cancer vaccines bit.ly/4k1eXyK
New aging tool maps organ-by-organ decline with clinical precision #longevity #longevityinnovation longevity.technology/news/new-aging…
If you’re wondering what epigenetic reprogramming is, it’s the turning on of a subset of embryonic genes (Sox2, Klf4, Oct4) that results in a reset of gene expression so old tissues regain their identity and hence function and heal like they are young again
What if the path to slowing aging wasn’t a drug, but replacing worn out parts? Our new paper out today in @NatureAging shows how this could one day work. We map a unified framework—from scaffolds & bioprinted tissues to pacemakers, xenotransplants & brain machine interfaces—for…
nature.com
Replacement as an aging intervention
Nature Aging - Lore et al. explore how biological and synthetic replacement therapies, from engineered tissues to advanced prosthetics, could restore aging cells and organs, offering strategies to...
Longevity company Unity Biotechnology provides new evidence their drug candidate clears old senescent cells in the retina providing lasting improvements in vision 👁️👁️ Longevity science is coming of age 👏
A baby has been born after being conceived via IVF performed by a machine, with a medical professional merely overseeing the process newscientist.com/article/247589…
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