d.
@biostackdev
Building @stackvity | digital twin for longevity
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If you had an idea that was going to outrage society, would you keep it to yourself?
Discovery and protein language model-guided design of hyperactive transposases go.nature.com/4gXLGEw
Senescence-resistant human mesenchymal progenitor cells counter aging in primates 🐒 👉 “This study provides initial evidence that genetically modified human mesenchymal progenitors can slow primate aging” cell.com/cell/fulltext/…
Scaling DNA synthesis with a microchip-based massively parallel synthesis system go.nature.com/3VKimYk
Cardiac ageing: from hallmarks to therapeutic opportunities academic.oup.com/cardiovascres/…
Mitochondrial integrity stands out as a major gatekeeper for the control of genetic, metabolic, and inflammatory homeostasis;
Inflammation and mitophagy are mitochondrial checkpoints to aging | Nature Communications nature.com/articles/s4146…
Integrative physiology of skeletal muscle for maintaining cognitive health physoc.onlinelibrary.wiley.com/doi/10.1113/JP…
Sarcopenia: age-related loss of skeletal muscle mass & function👇🏼 >reduced regenerative capacity >imbalance in protein turnover >alteration of muscle’s fat composition >increased reactive oxygen species >mitochondrial dysfunction >increased inflammation link.springer.com/article/10.100…
Dynamic fibroblast–immune interactions shape recovery after brain injury🔥 nature.com/articles/s4158…
I'm excited to finally share this work led by @FarahJaberH : Inactivation of Histone Chaperone HIRA Unmasks a Link Between Normal Embryonic Development of Melanoblasts and Maintenance of Adult Melanocyte Stem Cells. Published in Aging Cell. doi.org/10.1111/acel.7…
New aging tool maps organ-by-organ decline with clinical precision #longevity #longevityinnovation longevity.technology/news/new-aging…
If you’re wondering what epigenetic reprogramming is, it’s the turning on of a subset of embryonic genes (Sox2, Klf4, Oct4) that results in a reset of gene expression so old tissues regain their identity and hence function and heal like they are young again
What if the path to slowing aging wasn’t a drug, but replacing worn out parts? Our new paper out today in @NatureAging shows how this could one day work. We map a unified framework—from scaffolds & bioprinted tissues to pacemakers, xenotransplants & brain machine interfaces—for…
Longevity company Unity Biotechnology provides new evidence their drug candidate clears old senescent cells in the retina providing lasting improvements in vision 👁️👁️ Longevity science is coming of age 👏
A baby has been born after being conceived via IVF performed by a machine, with a medical professional merely overseeing the process newscientist.com/article/247589…
Amazing spinal cord development by Elizabeth Haynes & Jiaye He.
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