biostackdev's profile picture. Building @stackvity | digital twin for longevity

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@biostackdev

Building @stackvity | digital twin for longevity

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If you had an idea that was going to outrage society, would you keep it to yourself?


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The Lipid Brain Atlas is out now! If you think lipids are boring and membranes are all the same, prepare to be surprised. Led by Luca Fusar Bassini with Gioele La Manno's lab, we mapped membrane lipids in the mouse brain at high resolution. biorxiv.org/cgi/content/sh…

Gio_Dangel0's tweet image. The Lipid Brain Atlas is out now! If you think lipids are boring and membranes are all 
the same, prepare to be surprised. Led by Luca Fusar Bassini with Gioele La Manno's lab, we mapped membrane lipids in the mouse brain at high resolution.
biorxiv.org/cgi/content/sh…

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Discovery and protein language model-guided design of hyperactive transposases go.nature.com/4gXLGEw

NatureBiotech's tweet image. Discovery and protein language model-guided design of hyperactive transposases go.nature.com/4gXLGEw

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Senescence-resistant human mesenchymal progenitor cells counter aging in primates 🐒 👉 “This study provides initial evidence that genetically modified human mesenchymal progenitors can slow primate aging” cell.com/cell/fulltext/…

agingdoc1's tweet image. Senescence-resistant human mesenchymal progenitor cells counter aging in primates 🐒

👉 “This study provides initial evidence that genetically modified human mesenchymal progenitors can slow primate aging”

cell.com/cell/fulltext/…

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Scaling DNA synthesis with a microchip-based massively parallel synthesis system go.nature.com/3VKimYk

NatureBiotech's tweet image. Scaling DNA synthesis with a microchip-based massively parallel synthesis system go.nature.com/3VKimYk

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Cardiac ageing: from hallmarks to therapeutic opportunities academic.oup.com/cardiovascres/…

agingdoc1's tweet image. Cardiac ageing: from hallmarks to therapeutic opportunities

academic.oup.com/cardiovascres/…

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Mitochondrial integrity stands out as a major gatekeeper for the control of genetic, metabolic, and inflammatory homeostasis;

Madam_Mito's tweet image. Mitochondrial integrity stands out as a major gatekeeper for the control of genetic, metabolic, and inflammatory homeostasis;

Inflammation and mitophagy are mitochondrial checkpoints to aging | Nature Communications nature.com/articles/s4146…



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Integrative physiology of skeletal muscle for maintaining cognitive health physoc.onlinelibrary.wiley.com/doi/10.1113/JP…

ChristophBurch's tweet image. Integrative physiology of skeletal muscle for maintaining cognitive health
physoc.onlinelibrary.wiley.com/doi/10.1113/JP…

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Sarcopenia: age-related loss of skeletal muscle mass & function👇🏼 >reduced regenerative capacity >imbalance in protein turnover >alteration of muscle’s fat composition >increased reactive oxygen species >mitochondrial dysfunction >increased inflammation link.springer.com/article/10.100…

Omid_HopeUni's tweet image. Sarcopenia: age-related loss of skeletal muscle mass & function👇🏼

>reduced regenerative capacity
>imbalance in protein turnover
>alteration of muscle’s fat composition
>increased reactive oxygen species
>mitochondrial dysfunction 
>increased inflammation

link.springer.com/article/10.100…

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Dynamic fibroblast–immune interactions shape recovery after brain injury🔥 nature.com/articles/s4158…


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I'm excited to finally share this work led by @FarahJaberH : Inactivation of Histone Chaperone HIRA Unmasks a Link Between Normal Embryonic Development of Melanoblasts and Maintenance of Adult Melanocyte Stem Cells. Published in Aging Cell. doi.org/10.1111/acel.7…

AdamsBioAging's tweet image. I'm excited to finally share this work led by @FarahJaberH :  Inactivation of Histone Chaperone HIRA Unmasks a Link Between Normal Embryonic Development of Melanoblasts and Maintenance of Adult Melanocyte Stem Cells. Published in Aging Cell. doi.org/10.1111/acel.7…

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NEW content online! Recent advances in therapeutic cancer vaccines bit.ly/4k1eXyK

NatureRevCancer's tweet image. NEW content online! Recent advances in therapeutic cancer vaccines bit.ly/4k1eXyK

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Anticoagulants – Summary. manualofmedicine.com

drsthanus's tweet image. Anticoagulants – Summary.

manualofmedicine.com

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If you’re wondering what epigenetic reprogramming is, it’s the turning on of a subset of embryonic genes (Sox2, Klf4, Oct4) that results in a reset of gene expression so old tissues regain their identity and hence function and heal like they are young again


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What if the path to slowing aging wasn’t a drug, but replacing worn out parts? Our new paper out today in @NatureAging shows how this could one day work. We map a unified framework—from scaffolds & bioprinted tissues to pacemakers, xenotransplants & brain machine interfaces—for…

Sierra_Lore_'s tweet image. What if the path to slowing aging wasn’t a drug, but replacing worn out parts? 

Our new paper out today in @NatureAging shows how this could one day work. We map a unified framework—from scaffolds & bioprinted tissues to pacemakers, xenotransplants & brain machine interfaces—for…

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Longevity company Unity Biotechnology provides new evidence their drug candidate clears old senescent cells in the retina providing lasting improvements in vision 👁️👁️ Longevity science is coming of age 👏

davidasinclair's tweet image. Longevity company Unity Biotechnology provides new evidence their drug candidate clears old senescent cells in the retina providing lasting improvements in vision 👁️👁️ Longevity science is coming of age 👏

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Anesthesia gold

OGdukeneurosurg's tweet image. Anesthesia gold

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Hormones

OGdukeneurosurg's tweet image. Hormones

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Arterial Tree of Life

OGdukeneurosurg's tweet image. Arterial Tree of Life

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