#doacs zoekresultaten

Perioperative Management of Anticoagulants🩸 #AVK #DOACs

SeguraCardio's tweet image. Perioperative Management of Anticoagulants🩸

#AVK #DOACs

🔴Anticoagulation comparison chart 🔹Apixaban, Rivaroxaban, dabigatran, and warfarin ! Looking for a quick & convenient way to compare different #DOACs & #warfarin?! Look no further than NATF's #anticoagulation comparison chart! See the full chart at hubs.la/Q01vTd1y0

ZHeart11768530's tweet image. 🔴Anticoagulation comparison chart

🔹Apixaban, Rivaroxaban, dabigatran, and warfarin ! Looking for a quick & convenient way to compare different #DOACs & #warfarin?! Look no further than NATF's #anticoagulation comparison chart! See the full chart at hubs.la/Q01vTd1y0
ZHeart11768530's tweet image. 🔴Anticoagulation comparison chart

🔹Apixaban, Rivaroxaban, dabigatran, and warfarin ! Looking for a quick & convenient way to compare different #DOACs & #warfarin?! Look no further than NATF's #anticoagulation comparison chart! See the full chart at hubs.la/Q01vTd1y0

Thrombophilia & Anticoagulation Direct Oral anticoagulants doses #DOACs

AhmedKo45911157's tweet image. Thrombophilia & Anticoagulation
Direct Oral anticoagulants doses #DOACs

Data from the REWARF-STEMI pilot trial, together with a prespecified meta-analysis, indicated that #DOACs may offer similar efficacy and safety to warfarin for left ventricular thrombus after STEMI, pending confirmation in larger trials. #EIJBestOf #cardiotwitter

EuroInterventio's tweet image. Data from the REWARF-STEMI pilot trial, together with a prespecified meta-analysis, indicated that #DOACs may offer similar efficacy and safety to warfarin for left ventricular thrombus after STEMI, pending confirmation in larger trials. 
#EIJBestOf #cardiotwitter

New #BJA #editorial discussing the ASRA vs PAUSE-2 approaches to #DOACs with #neuraxialanaesthesia and deep peripheral nerve blocks (#PNBs) – can a shorter interruption period offer comparable safety? bjanaesthesia.org/article/S0007-…

BJAJournals's tweet image. New #BJA #editorial discussing the ASRA vs PAUSE-2 approaches to #DOACs with #neuraxialanaesthesia and deep peripheral nerve blocks (#PNBs) – can a shorter interruption period offer comparable safety? 

bjanaesthesia.org/article/S0007-…

🔎DOAC Drug Levels: When to Measure? Important clinical scenarios where drug level testing can guide management: 1️⃣ Urgent Procedures 🚨 2️⃣ Serious Bleeding 🩸 3️⃣ Acute Stroke 🧠 4️⃣ Overdose 💊 5️⃣ CKD & Drug Interactions 🩺 🔗 Decision-making tools for clinicians. #ASH24 #DOACs

AhmedKo45911157's tweet image. 🔎DOAC Drug Levels: When to Measure?
Important clinical scenarios where drug level testing can guide management:
1️⃣ Urgent Procedures 🚨
2️⃣ Serious Bleeding 🩸
3️⃣ Acute Stroke 🧠
4️⃣ Overdose 💊
5️⃣ CKD & Drug Interactions 🩺

🔗 Decision-making tools for clinicians.
#ASH24 #DOACs

Anticoagulation for post-STEMI LV thrombus This randomized comparison of rivaroxaban vs warfarin, paired with a prespecified pooled analysis of available RCTs, showed similar LVT resolution with #DOACs and no excess major bleeding, with pooled data suggesting numerically

EuroInterventio's tweet image. Anticoagulation for post-STEMI LV thrombus
This randomized comparison of rivaroxaban vs warfarin, paired with a prespecified pooled analysis of available RCTs, showed similar LVT resolution with #DOACs and no excess major bleeding, with pooled data suggesting numerically

DOACs, particularly apixaban, rise as an emerging alternative for VKAs in HM3-supported patients. What evidence do we have today? Read more. @LBlazquezArroyo @CVandenbriele #LVAD #Cardiology #DOACs #HeartFailure 🔗: jhltonline.org/article/S1053-…


🩸Severe Bleeding on #Anticoagulants? 🔹VKA➡️ Vit K 10mg IV +PCC   INR 2–3.9 ➡️25 IU/kg   INR ≥6 ➡️50 IU/kg 🔹Dabigatran ➡️Idarucizumab5g IV   💭Charcoal≤4h |💧Consider HD 🔹FXa Inhibitors➡️ Andexanet Alfa   400–800mg bolus➕ infusion   💭Charcoal≤4h #Bleeding #DOACs #Reversal

AhmedKo45911157's tweet image. 🩸Severe Bleeding on #Anticoagulants?
🔹VKA➡️ Vit K 10mg IV +PCC
  INR 2–3.9 ➡️25 IU/kg
  INR ≥6 ➡️50 IU/kg
🔹Dabigatran ➡️Idarucizumab5g IV
  💭Charcoal≤4h |💧Consider HD
🔹FXa Inhibitors➡️ Andexanet Alfa
  400–800mg bolus➕ infusion
  💭Charcoal≤4h
#Bleeding #DOACs #Reversal

🚨 📢 Beyond thrilled to share my latest publication in @JACCJournals as a first author, where we reviewed conditions in which #DOACs are ✅, 🚫 or❓as therapeutic options, based on recent #RCTs. 🧵 ⬇️ jacc.org/doi/full/10.10…

AntoineBejjani_'s tweet image. 🚨 📢 Beyond thrilled to share my latest publication in @JACCJournals as a first author, where we reviewed conditions in which #DOACs are ✅, 🚫 or❓as therapeutic options, based on recent #RCTs.

🧵 ⬇️ 

jacc.org/doi/full/10.10…

So many tips on anticoagulant choice by @GBarnesMD crammed into a few minutes. One key reminder --- #DOACs are NOT dose adjusted for VTE Rx. If significant CKD need to choose anticoagulant carefully #23FellowsApp

heatherlgornik's tweet image. So many tips on anticoagulant choice by @GBarnesMD crammed into a few minutes. One key reminder --- #DOACs are NOT dose adjusted for VTE Rx. If significant CKD need to choose anticoagulant carefully #23FellowsApp
heatherlgornik's tweet image. So many tips on anticoagulant choice by @GBarnesMD crammed into a few minutes. One key reminder --- #DOACs are NOT dose adjusted for VTE Rx. If significant CKD need to choose anticoagulant carefully #23FellowsApp
heatherlgornik's tweet image. So many tips on anticoagulant choice by @GBarnesMD crammed into a few minutes. One key reminder --- #DOACs are NOT dose adjusted for VTE Rx. If significant CKD need to choose anticoagulant carefully #23FellowsApp

#DOACs have revolutionized the mgmt of anticoagulation for pts as the gold standard for many disease processes. But not always When are DOACs not the most appropriate agent? Read more in this crucial piece for providers across #Medicine. bit.ly/48r7sv7 #JACC #cvCoag

JACCJournals's tweet image. #DOACs have revolutionized the mgmt of anticoagulation for pts as the gold standard for many disease processes. But not always

When are DOACs not the most appropriate agent? Read more in this crucial piece for providers across #Medicine. bit.ly/48r7sv7 #JACC #cvCoag

🩸 New Thrombo Trials! 🔹 Reduced-dose DOACs ≈ full-dose for VTE recurrence but didn’t meet non-inferiority; ↓ bleeding risk 🔹 PCC > plasma for bleeding control in cardiac surgery 🔹 Alteplase 4.5–24h: ↑ function in posterior stroke 🔗 thrombotrialfiles.substack.com/p/thrombo-tria… #VTE #DOACs

MedicinePods's tweet image. 🩸 New Thrombo Trials!  

🔹 Reduced-dose DOACs ≈ full-dose for VTE recurrence but didn’t meet non-inferiority; ↓ bleeding risk
🔹 PCC > plasma for bleeding control in cardiac surgery
🔹 Alteplase 4.5–24h: ↑ function in posterior stroke

🔗 thrombotrialfiles.substack.com/p/thrombo-tria…

#VTE #DOACs

💊DOACs Quick Guide 🟣Apixaban – BID, best in renal/liver issues 🔵Dabigatran – BID, ⚠️ avoid if CrCl ↓ 🟢 Edoxaban – QD, not for CrCl >95 🔴 Rivaroxaban – QD, high renal/liver clearance All approved for 🧠 AF stroke prevention & 🩸 VTE #DOACs #HemeTwitter #ASH #Anticoagulation

AhmedKo45911157's tweet image. 💊DOACs Quick Guide
🟣Apixaban – BID, best in renal/liver issues
🔵Dabigatran – BID, ⚠️ avoid if CrCl ↓
🟢 Edoxaban – QD, not for CrCl >95
🔴 Rivaroxaban – QD, high renal/liver clearance

All approved for 🧠 AF stroke prevention & 🩸 VTE
#DOACs #HemeTwitter #ASH #Anticoagulation

¿CUANDO “NO” DEBEN SER LOS #DOACS STANDARD DE TRATAMIENTO? Revisión @JACCJournals ✍🏽 🚫NO USAR -Sd. Antifosfolipídico -FA reumática -Válvula mecánica -LVAD -Embarazo o lactancia ⚠️PRECAUCIÓN -IRC terminal -Trombosis por catéter -Trombo VI -ACHD -Trombosis esplácnica

gonzaeperez's tweet image. ¿CUANDO “NO” DEBEN SER LOS #DOACS STANDARD DE TRATAMIENTO?
Revisión @JACCJournals ✍🏽

🚫NO USAR
-Sd. Antifosfolipídico
-FA reumática
-Válvula mecánica
-LVAD
-Embarazo o lactancia

⚠️PRECAUCIÓN
-IRC terminal
-Trombosis por catéter
-Trombo VI
-ACHD
-Trombosis esplácnica
gonzaeperez's tweet image. ¿CUANDO “NO” DEBEN SER LOS #DOACS STANDARD DE TRATAMIENTO?
Revisión @JACCJournals ✍🏽

🚫NO USAR
-Sd. Antifosfolipídico
-FA reumática
-Válvula mecánica
-LVAD
-Embarazo o lactancia

⚠️PRECAUCIÓN
-IRC terminal
-Trombosis por catéter
-Trombo VI
-ACHD
-Trombosis esplácnica
gonzaeperez's tweet image. ¿CUANDO “NO” DEBEN SER LOS #DOACS STANDARD DE TRATAMIENTO?
Revisión @JACCJournals ✍🏽

🚫NO USAR
-Sd. Antifosfolipídico
-FA reumática
-Válvula mecánica
-LVAD
-Embarazo o lactancia

⚠️PRECAUCIÓN
-IRC terminal
-Trombosis por catéter
-Trombo VI
-ACHD
-Trombosis esplácnica
gonzaeperez's tweet image. ¿CUANDO “NO” DEBEN SER LOS #DOACS STANDARD DE TRATAMIENTO?
Revisión @JACCJournals ✍🏽

🚫NO USAR
-Sd. Antifosfolipídico
-FA reumática
-Válvula mecánica
-LVAD
-Embarazo o lactancia

⚠️PRECAUCIÓN
-IRC terminal
-Trombosis por catéter
-Trombo VI
-ACHD
-Trombosis esplácnica

Anticoagulation with #DOACs vs. #VKAs in patients with left #ventricular thrombus: a new meta-analysis just published in #EHJPharmacotherapy 💊 bit.ly/3yVn3Gi @EditorEHJCVP @FeliceGragnano @DrErikGrove @GianluSava @jpkaski

ESC_Journals's tweet image. Anticoagulation with #DOACs vs. #VKAs in patients with left #ventricular thrombus: a new meta-analysis just published in #EHJPharmacotherapy 💊 bit.ly/3yVn3Gi 

@EditorEHJCVP @FeliceGragnano @DrErikGrove @GianluSava @jpkaski

#DOACs demonstrate comparable efficacy but exhibit different safety profiles. #Apixaban may confer an antithrombotic benefit w/out an ⬆️ risk for bleeding, distinguishing it from other contemporary anticoagulation strategies in pts w/ active cancer & #VTE bit.ly/3ShUbzo

JACCJournals's tweet image. #DOACs demonstrate comparable efficacy but exhibit different safety profiles. #Apixaban may confer an antithrombotic benefit w/out an ⬆️ risk for bleeding, distinguishing it from other contemporary anticoagulation strategies in pts w/ active cancer & #VTE bit.ly/3ShUbzo

The February issue is out now! Highlights include articles on the growing use of #AI in clinical #research, use of #DOACs in pediatric #thrombosis, public sector approaches to address unequal #CARTcell access, and more. Check out the full lineup here: ow.ly/J1cV50Y8gra

ASHClinicalNews's tweet image. The February issue is out now! Highlights include articles on the growing use of #AI in clinical #research, use of #DOACs in pediatric #thrombosis, public sector approaches to address unequal #CARTcell access, and more. Check out the full lineup here: ow.ly/J1cV50Y8gra

Fake psyop bullshit...Fuck Ukraine. #maga #ados #doacs #fba #black rumble.com/shorts/v6z49si…

Kurbee5's tweet image. Fake psyop bullshit...Fuck Ukraine.
#maga #ados #doacs #fba #black 

rumble.com/shorts/v6z49si…

rumble.com/v6ypoy4-fake-t… Watch the video and make your own judgement, stupid mf. It's a psyop. Fuck Ukraine, fuck you and fuck the pedos behind yet another, mind-fucking psyop... #ados #doacs #fba #black #maga

Kurbee5's tweet image. rumble.com/v6ypoy4-fake-t…

Watch the video and make your own judgement, stupid mf. It's a psyop. Fuck Ukraine, fuck you and fuck the pedos behind yet another, mind-fucking psyop...
#ados #doacs #fba #black #maga


We ARE the fkn Americans... #ados #doacs #fba ##BlackHistoryMonth

Moor with Emerald Cluster- Dresden Museum Mex. Indians; American Indian in European Dress; American Indians offer gifts- Brown Univ. Nottoway Tribe- Virginia Mayan God Ek Chuah- Chama Vase Olmec- El Negro Mayan God Ek Ahau- The Black Captain Cacaxtla Murals Bonampak Murals

Kurbee5's tweet image. Moor with Emerald Cluster- Dresden Museum 
Mex. Indians; American Indian in European Dress; American Indians offer gifts- Brown Univ.
Nottoway Tribe- Virginia
Mayan God Ek Chuah- Chama Vase
Olmec- El Negro
Mayan God Ek Ahau- The Black Captain
Cacaxtla Murals
Bonampak Murals


He could spy on the British during those times b/c he blended right in with the British. This is what British Royalty looked like during the George Washington era. You stupid, fucking, retarded, mind-fucked shitbags. armorial.bibsoc.org.uk/stamps02d1.htm… @AfricanArchives #ados #doacs #fba

Kurbee5's tweet image. He could spy on the British during those times b/c he blended right in with the British. This is what British Royalty looked like during the George Washington era. You stupid, fucking, retarded, mind-fucked shitbags. 
armorial.bibsoc.org.uk/stamps02d1.htm…
@AfricanArchives #ados #doacs #fba

James Armistead Lafayette, an enslaved Black American, served the Continental Army as a spy. He provided crucial intelligence that helped defeat the British and end the Revolutionary War. A THREAD

AfricanArchives's tweet image. James Armistead Lafayette, an enslaved Black American, served the Continental Army as a spy.

He provided crucial intelligence that helped defeat the British and end the Revolutionary War.

A THREAD


Fuck outta here, I got plenty of slurs for them mind-fucked, marshmallow monkey mfs...Try me #ados #doacs #fba #black #maga

What’s wild, is Black Americans don’t have slurs for other group of people. We don’t think about y’all enough to have any hatred deep enough to come up with a slur for any of y’all. I’ve been Black my whole life, and can’t think of one slur for any of you that we use.



JBR still on the Univ. of Toronto website. John Holles (1500s) link not working all of a sudden. This is 1700s British Royalty in the George Washington era. You stupid niggas still taking history lessons from them cave-apes? armorial.bibsoc.org.uk/stamps02d1.htm… #ados #doacs #fba #black #maga

Kurbee5's tweet image. JBR still on the Univ. of Toronto website. John Holles (1500s) link not working all of a sudden. This is 1700s British Royalty in the George Washington era. You stupid niggas still taking history lessons from them cave-apes?

armorial.bibsoc.org.uk/stamps02d1.htm…
#ados #doacs #fba #black #maga

Not surprised. It's what neander-apes do...#ados #doacs #fba #black #white

Kurbee5's tweet image. Not surprised. It's what neander-apes do...#ados #doacs #fba #black #white

🚨🇬🇧 The Viral Moment last night at the UK BAFTA Awards - where somebody in the audience allegedly with Tourette’s - shouted the ‘N’ word ‼️



All European artifacts here...Who do you think would have European surnames first? The people in the castle? Or the invading sasquatch shitbags on the left? Still think Americans got their names from a race of test-tube neander-chimps? Stupid mfs. #ados #doacs #fba #black #maga

Kurbee5's tweet image. All European artifacts here...Who do you think would have European surnames first? The people in the castle? Or the invading sasquatch shitbags on the left? Still think Americans got their names from a race of test-tube neander-chimps? Stupid mfs. #ados #doacs #fba #black #maga
Kurbee5's tweet image. All European artifacts here...Who do you think would have European surnames first? The people in the castle? Or the invading sasquatch shitbags on the left? Still think Americans got their names from a race of test-tube neander-chimps? Stupid mfs. #ados #doacs #fba #black #maga
Kurbee5's tweet image. All European artifacts here...Who do you think would have European surnames first? The people in the castle? Or the invading sasquatch shitbags on the left? Still think Americans got their names from a race of test-tube neander-chimps? Stupid mfs. #ados #doacs #fba #black #maga

These swine-skinned, sasquatch shitbags deify themselves as Jesus fkn Christ in a whitewashed religion and swear that they were the mf Egyptians... #ados #doacs #fba #black

The Wodewosen/Wild Men Or "Bigfoot" And The Black European Moors 💯🦅💨🙌🏾🗡️



Can't really believe anything that them pig-faced, pedo, swine-skinned, marshmallow, monkey mfs have to say have to say about "history"....#ados #doacs #fba #black #maga

Kurbee5's tweet image. Can't really believe anything that them pig-faced, pedo, swine-skinned, marshmallow, monkey mfs have to say have to say about "history"....#ados #doacs #fba #black #maga
Kurbee5's tweet image. Can't really believe anything that them pig-faced, pedo, swine-skinned, marshmallow, monkey mfs have to say have to say about "history"....#ados #doacs #fba #black #maga

Crackas been lying since the literal beginning of the inception of the USA but we got niggas who believe their version of American history 😂😂



Europeans and Americans already had an ethnogenesis on both sides of Atlantis, long before Cristobal fkn Colon. Check my media files dummy...#ados #doacs #fba #black #history

Kurbee5's tweet image. Europeans and Americans already had an ethnogenesis on both sides of Atlantis, long before Cristobal fkn Colon. Check my media files dummy...#ados #doacs #fba #black #history
Kurbee5's tweet image. Europeans and Americans already had an ethnogenesis on both sides of Atlantis, long before Cristobal fkn Colon. Check my media files dummy...#ados #doacs #fba #black #history

Perioperative Management of Anticoagulants🩸 #AVK #DOACs

SeguraCardio's tweet image. Perioperative Management of Anticoagulants🩸

#AVK #DOACs

🔴Anticoagulation comparison chart 🔹Apixaban, Rivaroxaban, dabigatran, and warfarin ! Looking for a quick & convenient way to compare different #DOACs & #warfarin?! Look no further than NATF's #anticoagulation comparison chart! See the full chart at hubs.la/Q01vTd1y0

ZHeart11768530's tweet image. 🔴Anticoagulation comparison chart

🔹Apixaban, Rivaroxaban, dabigatran, and warfarin ! Looking for a quick & convenient way to compare different #DOACs & #warfarin?! Look no further than NATF's #anticoagulation comparison chart! See the full chart at hubs.la/Q01vTd1y0
ZHeart11768530's tweet image. 🔴Anticoagulation comparison chart

🔹Apixaban, Rivaroxaban, dabigatran, and warfarin ! Looking for a quick & convenient way to compare different #DOACs & #warfarin?! Look no further than NATF's #anticoagulation comparison chart! See the full chart at hubs.la/Q01vTd1y0

Thrombophilia & Anticoagulation Direct Oral anticoagulants doses #DOACs

AhmedKo45911157's tweet image. Thrombophilia & Anticoagulation
Direct Oral anticoagulants doses #DOACs

Anticoagulation for post-STEMI LV thrombus This randomized comparison of rivaroxaban vs warfarin, paired with a prespecified pooled analysis of available RCTs, showed similar LVT resolution with #DOACs and no excess major bleeding, with pooled data suggesting numerically

EuroInterventio's tweet image. Anticoagulation for post-STEMI LV thrombus
This randomized comparison of rivaroxaban vs warfarin, paired with a prespecified pooled analysis of available RCTs, showed similar LVT resolution with #DOACs and no excess major bleeding, with pooled data suggesting numerically

New #BJA #editorial discussing the ASRA vs PAUSE-2 approaches to #DOACs with #neuraxialanaesthesia and deep peripheral nerve blocks (#PNBs) – can a shorter interruption period offer comparable safety? bjanaesthesia.org/article/S0007-…

BJAJournals's tweet image. New #BJA #editorial discussing the ASRA vs PAUSE-2 approaches to #DOACs with #neuraxialanaesthesia and deep peripheral nerve blocks (#PNBs) – can a shorter interruption period offer comparable safety? 

bjanaesthesia.org/article/S0007-…

Data from the REWARF-STEMI pilot trial, together with a prespecified meta-analysis, indicated that #DOACs may offer similar efficacy and safety to warfarin for left ventricular thrombus after STEMI, pending confirmation in larger trials. #EIJBestOf #cardiotwitter

EuroInterventio's tweet image. Data from the REWARF-STEMI pilot trial, together with a prespecified meta-analysis, indicated that #DOACs may offer similar efficacy and safety to warfarin for left ventricular thrombus after STEMI, pending confirmation in larger trials. 
#EIJBestOf #cardiotwitter

🔴 Oral anticoagulation in pts with LV thrombus – a SA & MA The use of #DOACs not ass w/ a significant diff. in stroke/ systemic embolism or thrombus resolution Vs. to #VKA The use of DOACs ass. w/ a lower rate of all cause death & fewer blding events bit.ly/3yVn3Gi

ZHeart11768530's tweet image. 🔴 Oral anticoagulation in pts with LV thrombus – a SA & MA 

The use of #DOACs not ass w/ a significant diff. in stroke/ systemic embolism or thrombus resolution Vs. to #VKA 

The use of DOACs  ass. w/ a lower rate of all cause death & fewer blding events bit.ly/3yVn3Gi

Anticoagulation with #DOACs vs. #VKAs in patients with left #ventricular thrombus: a new meta-analysis just published in #EHJPharmacotherapy 💊 bit.ly/3yVn3Gi @EditorEHJCVP @FeliceGragnano @DrErikGrove @GianluSava @jpkaski

ESC_Journals's tweet image. Anticoagulation with #DOACs vs. #VKAs in patients with left #ventricular thrombus: a new meta-analysis just published in #EHJPharmacotherapy 💊 bit.ly/3yVn3Gi 

@EditorEHJCVP @FeliceGragnano @DrErikGrove @GianluSava @jpkaski

ResearchTuesday @FishingNeurons et al @ELAN_Trial investigators suggest starting #DOACs for #NVAF early after stroke (minor/moderate AIS <2d, major AIS day 6/7) may lead to lower rates of strokes (1.4 vs 2.5%) w/o higher sICH (0.2 vs 0.2%) @ESOstroke @NEJM tinyurl.com/2p8nyfwx

svinsociety's tweet image. ResearchTuesday @FishingNeurons et al @ELAN_Trial investigators suggest starting #DOACs for #NVAF early after stroke (minor/moderate AIS &amp;lt;2d, major AIS day 6/7) may lead to lower rates of strokes (1.4 vs 2.5%) w/o higher sICH (0.2 vs 0.2%) @ESOstroke @NEJM tinyurl.com/2p8nyfwx

🔴 Updated Rapid Resource: Appropriate Use of DOACs in the Pediatric Population! #OpenAccess 🔹Check out this 2-page summary on #DOACs in #pediatrics: bit.ly/45Icpzi #CardioTwitter #Cardiology #MedEd #CriticalCare #FOAMcc #FOAMed #surgery

ZHeart11768530's tweet image. 🔴 Updated Rapid Resource: Appropriate Use of DOACs in the Pediatric Population! #OpenAccess

🔹Check out this 2-page summary on #DOACs in #pediatrics: bit.ly/45Icpzi

#CardioTwitter #Cardiology  #MedEd  #CriticalCare #FOAMcc #FOAMed  #surgery

#DOACs have revolutionized the mgmt of anticoagulation for pts as the gold standard for many disease processes. But not always When are DOACs not the most appropriate agent? Read more in this crucial piece for providers across #Medicine. bit.ly/48r7sv7 #JACC #cvCoag

JACCJournals's tweet image. #DOACs have revolutionized the mgmt of anticoagulation for pts as the gold standard for many disease processes. But not always

When are DOACs not the most appropriate agent? Read more in this crucial piece for providers across #Medicine. bit.ly/48r7sv7 #JACC #cvCoag

#DOACs demonstrate comparable efficacy but exhibit different safety profiles. #Apixaban may confer an antithrombotic benefit w/out an ⬆️ risk for bleeding, distinguishing it from other contemporary anticoagulation strategies in pts w/ active cancer & #VTE bit.ly/3ShUbzo

JACCJournals's tweet image. #DOACs demonstrate comparable efficacy but exhibit different safety profiles. #Apixaban may confer an antithrombotic benefit w/out an ⬆️ risk for bleeding, distinguishing it from other contemporary anticoagulation strategies in pts w/ active cancer &amp;amp; #VTE bit.ly/3ShUbzo

🔎DOAC Drug Levels: When to Measure? Important clinical scenarios where drug level testing can guide management: 1️⃣ Urgent Procedures 🚨 2️⃣ Serious Bleeding 🩸 3️⃣ Acute Stroke 🧠 4️⃣ Overdose 💊 5️⃣ CKD & Drug Interactions 🩺 🔗 Decision-making tools for clinicians. #ASH24 #DOACs

AhmedKo45911157's tweet image. 🔎DOAC Drug Levels: When to Measure?
Important clinical scenarios where drug level testing can guide management:
1️⃣ Urgent Procedures 🚨
2️⃣ Serious Bleeding 🩸
3️⃣ Acute Stroke 🧠
4️⃣ Overdose 💊
5️⃣ CKD &amp;amp; Drug Interactions 🩺

🔗 Decision-making tools for clinicians.
#ASH24 #DOACs

In this meta-analysis of #RCTs of patients with thrombotic #antiphospholipid syndrome, treatment with #DOACs had a higher risk of arterial thrombosis than #VKAs. bit.ly/3vAYFF6 #JACC #VTE #cvVTE #CardioTwitter

JACCJournals's tweet image. In this meta-analysis of #RCTs of patients with thrombotic #antiphospholipid syndrome, treatment with #DOACs had a higher risk of arterial thrombosis than #VKAs. bit.ly/3vAYFF6 

#JACC #VTE #cvVTE #CardioTwitter

🩸Severe Bleeding on #Anticoagulants? 🔹VKA➡️ Vit K 10mg IV +PCC   INR 2–3.9 ➡️25 IU/kg   INR ≥6 ➡️50 IU/kg 🔹Dabigatran ➡️Idarucizumab5g IV   💭Charcoal≤4h |💧Consider HD 🔹FXa Inhibitors➡️ Andexanet Alfa   400–800mg bolus➕ infusion   💭Charcoal≤4h #Bleeding #DOACs #Reversal

AhmedKo45911157's tweet image. 🩸Severe Bleeding on #Anticoagulants?
🔹VKA➡️ Vit K 10mg IV +PCC
  INR 2–3.9 ➡️25 IU/kg
  INR ≥6 ➡️50 IU/kg
🔹Dabigatran ➡️Idarucizumab5g IV
  💭Charcoal≤4h |💧Consider HD
🔹FXa Inhibitors➡️ Andexanet Alfa
  400–800mg bolus➕ infusion
  💭Charcoal≤4h
#Bleeding #DOACs #Reversal

ICYMI: #DOACs demonstrate comparable efficacy in treating and preventing recurrent #VTE but exhibit different safety profiles. #Apixaban may confer an antithrombotic benefit w/out an ⬆️ risk for bleeding. bit.ly/3ShUbzo #JACCCardioOnc #cvCoag

JACCJournals's tweet image. ICYMI: #DOACs demonstrate comparable efficacy in treating and preventing recurrent #VTE but exhibit different safety profiles. #Apixaban may confer an antithrombotic benefit w/out an ⬆️ risk for bleeding. bit.ly/3ShUbzo

#JACCCardioOnc #cvCoag

🩸 New Thrombo Trials! 🔹 Reduced-dose DOACs ≈ full-dose for VTE recurrence but didn’t meet non-inferiority; ↓ bleeding risk 🔹 PCC > plasma for bleeding control in cardiac surgery 🔹 Alteplase 4.5–24h: ↑ function in posterior stroke 🔗 thrombotrialfiles.substack.com/p/thrombo-tria… #VTE #DOACs

MedicinePods's tweet image. 🩸 New Thrombo Trials!  

🔹 Reduced-dose DOACs ≈ full-dose for VTE recurrence but didn’t meet non-inferiority; ↓ bleeding risk
🔹 PCC &amp;gt; plasma for bleeding control in cardiac surgery
🔹 Alteplase 4.5–24h: ↑ function in posterior stroke

🔗 thrombotrialfiles.substack.com/p/thrombo-tria…

#VTE #DOACs

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