#extracellularmatrix search results
#Extracellularmatrix interaction with cell membrane receptors has mechanoresponsive effects on the #cytoskeleton to shield the nucleus from deforming & signals. Video & research by @ZanettaKechagia et al @PCusachs lab @IBECBarcelona in @naturemethods. On bpod.org.uk/archive/2023/1…
'Making tracks: #microglia and the #ExtracellularMatrix' Lauren K. Wareham & David J. Calkins @VUMCDiscoveries #neurodegeneration …arneurodegeneration.biomedcentral.com/articles/10.11…
📢 Call for paper submissions in @nature_npj npj Biological Physics & Mechanics special collection on: Mechanobiology of the Extracellular Matrix! 📅 Deadline: 14 May 2026 🔗 nature.com/collections/ba… More info👇(1/7) #ExtracellularMatrix #ECM #Mechanobiology #natureportfolio
🔬 Experiments detail the development of a novel #ExtracellularMatrix hydrogel, which entailed incorporation of adipose-derived #mesenchymal stem cell-derived exosomes into an ECM hydrogel. @AdvSciNews: ➡️ bit.ly/48niZfe
Building a Lung Tumor Microenvironment with Double-network #Hydrogel Decellularized Lung #ExtraCellularMatrix + Sulfated Alginate, mimicking Glycosaminoglycan A549 cells ⏫Proliferation, Both Epithelial & Mesenchymal markers, Mucins, Fibronectin, Stemness…
#EndothelialCell Mechanics & Dynamics in #Angiogenesis An excellent up-to-date synthesis & insight!😆 👉Water influx of Tip cells to regulate cytoplasmic viscosity & actin dynamics 👉Mechanical plasticity & deformability of #ExtraCellularMatrix 👉#YAP/TAZ in mechanochemical…
Did you know that there is a complex interplay between mammalian lymph node (LN) fibroblastic reticular cells and their unique #ExtracellularMatrix? 📚 Read about it in @TrendsImmuno: bit.ly/3Xn2ewU
The chitinase-like proteins Ym1 and Ym2 drive #allergen-induced #ExtracellularMatrix remodeling and airway thickening in mice, independent of IL-13 or IL-17A. Learn more in Science #Immunology: scim.ag/4ny7Hvu
Rhobo6👹 An omnipotent cell-impermeable dye labels diol/glycan of #ExtraCellularMatrix ✅Fibrillar collagen/fibronectin, BM, sulfated proteoglycan, even HA weakly 👉STED microscopy-compatible 👉Penetrate mm-thick🐭muscle ex vivo 👉Retro-orbital injection to label the ECM…
Remodeling & stiffening of the #ExtracellularMatrix is a well-recognized modulator of breast cancer progression. But how are these changes converted into biochemical signals that direct tumor cell migration and #metastasis? Insights in @emboreports: 📗 shorturl.at/fmsLZ
#ExtraCellularMatrix #ArterialAging Sox9 #SmoothMuscleCell Sox9➡️#ExtracellularVesicle (PLOD3)➡️ECM Stiffness➡️SMC #Senescence & likely #ArterialStiffening +A feedforward loop Senscence+#MatrixStiffness⏫Sox9 expression & nucleation Senescent #SmoothMuscleCell, when seeded on…
Decellularized extracellular matrix as a drug delivery carrier. | Antonios G. Mikos @Rice_BIOE | [50 days' free access] #ExtracellularMatrix kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…
![JCRnEDITORS's tweet image. Decellularized extracellular matrix as a drug delivery carrier.
| Antonios G. Mikos @Rice_BIOE |
[50 days' free access]
#ExtracellularMatrix
kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…](https://pbs.twimg.com/media/GnRr7osasAAiOj3.jpg)
The authors of this @CellReports study found that mechanistically, #fibroblast activation protein was localized at invadopodia and required for invadopodia-mediated #ExtracellularMatrix degradation, independent of its proteolytic activity. 📓 bit.ly/3QmG4qs
#Topical pan-lysyl oxidase inhibition with PXS-6302 was generally well tolerated in mature scars, reducing collagen cross-linking and altering #ExtracellularMatrix measures over three months. @sciencetm doi.org/g93hcj medicalxpress.com/news/2025-09-p…
Ready to present our work on #ExtracellularMatrix and cell movement at the @SECF_fisiologia and FEPS Conference in #Granada. @GlioMatrixLab @AchucarroGlia
#Senescence #Fibrosis p21 controls collagen #ExtraCellularMatrix deposition in Both Senescent & Proliferating cells in #PulmonaryFibrosis Germline p21 KO🐭or 🐭carrying doxycycline-inducible p21 shRNA are protected against bleomycin-induced lung fibrosis ⏬DNA damage…
#LongRangeBiomechanics #ActiveNematics Use liquid crystalline (LC, RM257) polymer networks to segregate mechanical/stiffness anisotropy from contact guidance of #ExtraCellularMatrix As LC networks have a mean nanoscale ~2 nm below minimal threshold (35 nm) of contact guidance…
This work presents a comprehensive proteomic analysis of the liver #ExtracellularMatrix across different age stages, uncovering significant age-related changes. 🤩 Check it out: bit.ly/4etnOao
Beyond genetics: driving cancer with the tumour microenvironment behind the wheel nature.com/articles/s4156… #extracellularmatrix #ECM
Read the latest in JHC: "Immunohistochemical Assessment of Cardiac Macrophages in the Aged Fischer 344 Rat." Click to read: bit.ly/4qvjnl8 #immunohistochemistry #extracellularmatrix #macrophages
#Letter in @MedComm_MC Collagen XII is Commonly Downregulated in the Dermal Extracellular Matrix in Diverse Skin Pathologies➡️doi.org/10.1002/mco2.7… #ExtracellularMatrix #ECM #SquamousCellCarcinoma #Collagen #Skin #Pathology #Laminin
Read the latest in JHC: "Immunohistochemical Assessment of Cardiac Macrophages in the Aged Fischer 344 Rat." Click to read: bit.ly/4qvjnl8 #immunohistochemistry #extracellularmatrix #macrophages
Read the latest in JHC: "Immunohistochemical Assessment of Cardiac Macrophages in the Aged Fischer 344 Rat." Click to read: bit.ly/4qvjnl8 #immunohistochemistry #extracellularmatrix #macrophages
📢 #highlycited paper 📚 #ExtracellularMatrix Tunes the Regenerative Potential of #FetalStemCells 🔗 mdpi.com/2076-3417/14/5… 👨🔬 by Yixuan Amy Pei et al. 🏫 @WestVirginiaU/ University of Pennsylvania #differentiation #fetalnucleuspulposuscell
⭐Interesting Article: Matrix Stiffness Affects Spheroid Invasion, Collagen Remodeling, and Effective Reach of Stress into ECM 🎓by Prof. Schmidt et al., from @UniLeidenNews, The Netherlands 🗒️Read more: mdpi.com/2674-1172/4/2/… #tumoroid; #extracellularmatrix; #mechanobiology
📅 Submission deadline: 14 May 2026 🔗 Learn more & submit here: nature.com/collections/ba… #ExtracellularMatrix #ECM #Mechanobiology #natureportfolio #Biophysics #TissueEngineering #Biomechanics #RegenerativeMedicine #npjBiologicalPhysicsAndMechanics (7/7)
📢 Call for paper submissions in @nature_npj npj Biological Physics & Mechanics special collection on: Mechanobiology of the Extracellular Matrix! 📅 Deadline: 14 May 2026 🔗 nature.com/collections/ba… More info👇(1/7) #ExtracellularMatrix #ECM #Mechanobiology #natureportfolio
New in JHC: "Stromal Cells, Extracellular Matrix Components, and Adenosine A3 Receptor in Prostate Biopsies: Association With Histological Grade, PSA Levels, and Clinical Tumor Stage." Click to read: bit.ly/3VEmrNr #extracellularmatrix #prostatecancer…
'Making tracks: #microglia and the #ExtracellularMatrix' Lauren K. Wareham & David J. Calkins @VUMCDiscoveries #neurodegeneration …arneurodegeneration.biomedcentral.com/articles/10.11…
The chitinase-like proteins Ym1 and Ym2 drive #allergen-induced #ExtracellularMatrix remodeling and airway thickening in mice, independent of IL-13 or IL-17A. Learn more in Science #Immunology: scim.ag/4ny7Hvu
New in JHC: "Stromal Cells, Extracellular Matrix Components, and Adenosine A3 Receptor in Prostate Biopsies: Association With Histological Grade, PSA Levels, and Clinical Tumor Stage." Click to read: bit.ly/3VEmrNr #extracellularmatrix #prostatecancer…
New in JHC: "Stromal Cells, Extracellular Matrix Components, and Adenosine A3 Receptor in Prostate Biopsies: Association With Histological Grade, PSA Levels, and Clinical Tumor Stage." Click to read: bit.ly/3VEmrNr #extracellularmatrix #prostatecancer #stromalcells
#Topical pan-lysyl oxidase inhibition with PXS-6302 was generally well tolerated in mature scars, reducing collagen cross-linking and altering #ExtracellularMatrix measures over three months. @sciencetm doi.org/g93hcj medicalxpress.com/news/2025-09-p…
New in JHC: "Stromal Cells, Extracellular Matrix Components, and Adenosine A3 Receptor in Prostate Biopsies: Association With Histological Grade, PSA Levels, and Clinical Tumor Stage." Click to read: bit.ly/3VEmrNr #extracellularmatrix #prostatecancer #stromalcells
#LongRangeBiomechanics #ActiveNematics Use liquid crystalline (LC, RM257) polymer networks to segregate mechanical/stiffness anisotropy from contact guidance of #ExtraCellularMatrix As LC networks have a mean nanoscale ~2 nm below minimal threshold (35 nm) of contact guidance…
Recently published: Inhibition of #ExtracellularMatrix Protein Fibulin-3 Reduces Immunosuppressive Signaling and Increases Macrophage Activation in #Glioblastoma, by Mariano S. Viapiano and colleagues. doi.org/10.1158/2767-9… @UpstateNews #Immunosuppression #OpenAccess
#Fluorescent imaging of green algae reveals that their #ExtracellularMatrix forms a foam-like network, highlighting how #MulticellularOrganisms achieve precise shapes from variable cellular behavior. @Cambridge_Uni @PNASNews doi.org/g9w3n2 phys.org/news/2025-08-a…
🤔Check out this Systematic Review: Matrigel Tunes H9 Stem Cell-Derived Human Cerebral Organoid Development 🎓by Dr. Keung et al, from North Carolina State University, USA 🗒️Read more: brnw.ch/21wUPgY #cerebralorganoids; #Matrigel; #extracellularmatrix; #development
Anti-isoDGR immunotherapy stabilizes Aged 🐭#BloodBrainBarrier #ExtraCellularMatrix Protein Deamidation Asn-Gly-Arg/NRG➡️isoaspartate-Gly-Arg/isoDGR ⏫in #Aging Exogenous isoDGR on cultured #EndothelialCell 👉Actin cytoskeletal re-organization/collapse 👉Inflammation…
'Making tracks: #microglia and the #ExtracellularMatrix' Lauren K. Wareham & David J. Calkins @VUMCDiscoveries #neurodegeneration …arneurodegeneration.biomedcentral.com/articles/10.11…
🔬 Experiments detail the development of a novel #ExtracellularMatrix hydrogel, which entailed incorporation of adipose-derived #mesenchymal stem cell-derived exosomes into an ECM hydrogel. @AdvSciNews: ➡️ bit.ly/48niZfe
Did you know that there is a complex interplay between mammalian lymph node (LN) fibroblastic reticular cells and their unique #ExtracellularMatrix? 📚 Read about it in @TrendsImmuno: bit.ly/3Xn2ewU
The chitinase-like proteins Ym1 and Ym2 drive #allergen-induced #ExtracellularMatrix remodeling and airway thickening in mice, independent of IL-13 or IL-17A. Learn more in Science #Immunology: scim.ag/4ny7Hvu
Remodeling & stiffening of the #ExtracellularMatrix is a well-recognized modulator of breast cancer progression. But how are these changes converted into biochemical signals that direct tumor cell migration and #metastasis? Insights in @emboreports: 📗 shorturl.at/fmsLZ
Study in #zebrafish shows the #heartbeat's mechanical forces remodel the developing heart's #extracellularmatrix. Image & research by Alessandra Gentile & @MargaAlbu et al @StainierLab @mpi_hlr @GunawanLab @wwu_muenster in @Dev_journal. On bpod.org.uk/archive/2024/7…
At Number 4 in the countdown of our most discussed articles of 2022 - A glitch in the matrix: the pivotal role for #ExtracellularMatrix remodeling during muscle #hypertrophy - ow.ly/oyfy50Mzqjo #collagen #SkeletalMuscle @ChrisFryPhD @NickTThomas @KevinMurachPhD
Leading Edge: Protein called SAM68 plays key role in #bloodvessel wall #cell interaction with the #extracellularmatrix regulating cell remodelling & migration. Image & research by @RekadZeinab et al @Univ_CotedAzur in @elife. On bpod.org.uk/archive/2023/9…
Proteome profiles of intramuscular connective tissue: influence of #aging and physical training (Yeung et al. @ccstorytime) - new in @japplphysiol's Aging and Adaptation to #Exercise collection ow.ly/Yymj50OcEJy #extracellularmatrix #skeletalmuscle
Differential remodelling in small and large murine airways revealed by novel whole lung airway analysis (@amandatatler, @BindiBrook et al. @UniofNottingham) - just accepted in @AJPLung ow.ly/Oye650Migiy #asthma #airwaysmoothmuscle #extracellularmatrix
The authors of this @CellReports study found that mechanistically, #fibroblast activation protein was localized at invadopodia and required for invadopodia-mediated #ExtracellularMatrix degradation, independent of its proteolytic activity. 📓 bit.ly/3QmG4qs
New in @AJPCellPhys: Dudek et al. discuss new work linking the extracellular matrix w/ circadian clocks and how this relates to #ageing and age-related diseases. ow.ly/BZ7w50OzyOL @wtccmr @FBMH_UoM #CircadianRhythm #ExtracellularMatrix #Aging #Homeostasis #ArticlesinPress
New in @AJPLung: Age-associated Differences in the Human #Lung 🫁Extracellular Matrix (Ngassie et al.) ow.ly/vuhY50NHawC @MaunickK @gosensr @JanetteKBurgess @campusgr_ @UBC @lunduniversity @MayoClinic #Aging #ExtracellularMatrix #AirwayWall #Parenchyma
#Research by Kieran P. Normoyle (@MGHNeurology @harvardmed) et al. examines displacement of extracellular chloride by immobile anionic constituents of the brain's #extracellularmatrix 🧠 🔬 📜 Read it here: buff.ly/4aJyBLX
#ThrowbackThursday Special Topic: Endothelial Cell and Pericyte Homeostasis and Pathogenesis article in JHC: "Diabetes as a Pancreatic Microvascular Disease—A Pericytic Perspective." Click to read for FREE: bit.ly/3TVF13C #diabetes #extracellularmatrix #ecmatrix
#Organoids grown on hydrogel with tuneable mechanical properties reveal #extracellularmatrix forces in guiding formation of sensory #epithelium. Image & research by Mingyu Xia, Mingxuan Wu & Yuanrong Li et al @FudanUniv @ZJU_China in @ScienceAdvances. On bpod.org.uk/archive/2023/1…
In the August issue: The Interplay Between #ExtracellularMatrix Remodeling and Cancer Therapeutics. bit.ly/3M91iX0 @Prakash_UTwente @ShakedYuval @UTwente @TechnionLive.
New in @AJPCellPhys: Becker et al. used marker-independent #RamanMicrospectroscopy (RMS) to explore the underlying molecular & cellular mechanisms of #cardiomyopathies. ow.ly/gE0P50OSxy0 @dgsomucla @UCLAHealth @uni_tue #extracellularmatrix #collagen #ArticlesinPress
🧪 Biomaterials are important when developing disease models of organs rich in #ExtracellularMatrix, like the liver. The authors #review recent and cutting-edge #biomaterials used for creating in vitro models of human #LiverFibrosis! @advancematerial | bitly.ws/32kBC
Nuclear Warp: How the nucleus of #dendriticcells deform to enable migration between cells & #extracellularmatrix on their way to activate #Tcells #immuneresponse. Still & research by Harry Warner et al @univgroningen in @CellReports. On bpod.org.uk/archive/2024/4…
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