#cryoem search results
🔬 We are looking for candidates for two open positions in the Tomáš Kouba Group. The #cryoEM core facility studies 3D structure of proteins and their complexes using single particle analysis. See more on the #IT specialist position ► uochb.cz/en/open-positi… ⤵️ See more on
Evidence for Epibatidine Binding to the Desensitization Gate in α7 nAChR from Molecular Dynamics Simulations and Cryo-EM #MolecularDynamics #CryoEM pubs.acs.org/doi/10.1021/ac… #JCIM Vol66 Issue3 #Letter
Our structural biology editors welcome studies spanning #cryoEM, crystallography and NMR, macromolecular dynamics, the evolution of function and specificity in molecular systems and more. See what we publish in Structural Biology ⬇️ elifesciences.org/subjects/struc…
elifesciences.org
Structural Biology and Molecular Biophysics
eLife reviews research that uses techniques including X-ray crystallography, cryo-EM and single-molecule methods. Learn more about what we review and sign up for the latest research.
Muñoz-Hernández, Xu, Wieczorek et al. report #cryoEM structures revealing how NEDD1’s C terminus forms an α-helical tetramer that docks onto the γ-TuRC without inducing major conformational changes in the complex during its recruitment to MTOCs hubs.ly/Q03nCNXc0
Kenworthy et al @MedicineUVA explore the evolutionary history of caveolins. Using computational predictions & #CryoEM, the authors show both animal & choanoflagellate caveolins assemble into amphipathic disks composed of seven conserved structural elements hubs.la/Q03BN8r40
Capturing enzymes in motion The structure and dynamics of the ACE enzyme revealed by #CryoEM and molecular simulations. elifesciences.org/articles/10872…
Deciphering Protein Secondary Structures and Nucleic Acids in Cryo-EM Maps Using Deep Learning #DeepLearning #CryoEM pubs.acs.org/doi/10.1021/ac… #JCIM Vol65 Issue3 #Bioinformatics
How does the metabolic receptor #HCAR1 become activated? Researchers harness #CryoEM to examine HCAR1 unbound and bound to lactate or a synthetic activator and show that the receptor becomes self-activated through rearrangement of extracellular loop 2. scim.ag/4suF99n
A new mechanism of protein degradation: revealing how the proteasome recognizes branched ubiquitin chains sinica.edu.tw/en/news_conten… #CryoEM #proteasome #ubiquitin @IBCSinica
New #CryoEM discoveries are decoding the structural properties and evolution of the TSC2 protein complex, which acts as a key brake on the cell growth-promoting #mTORC1 signaling pathway. @lab_manning @HarvardChanSPH Check out the Review: scim.ag/46CKN0J
Cryo-EM Structure Illuminates How a Designed Peptide Precisely Pauses the Ribosome sinica.edu.tw/en/news_conten… #CryoEM #Ribosome #eRAP @IBCSinica
Time-resolved #cryoEM can resolve protein motion on millisecond or even microsecond timescales, but the need for highly specialized tools and skills limits the method’s reach. By Michael Eisenstein. nature.com/articles/d4158…
The new Leopard-EM software package for 2D template matching has been written with extensibility at the forefront @usc @ActaCrystD @IUCr #InSituStructuralBiology #CryoEM #CryoET doi.org/10.1107/S20597…
EMS is pleased to announce a series of webinars in cooperation with our colleagues at Quorum, specialists in sample preparation for EM. All webinars are free with registration. Details and registration: hubs.la/Q04dy0Mp0 #EMShasit #emsamplepreparation #cryoem #SEM #FIB
#BPS2026 Newsroom Spotlight - Scientists Show How Your Body Senses Cold - And Why Menthol Feels Cool @huykjoon_lee_kr @cggpark91 @jgfedor87 @dukemedschool #cryoelectronmicroscopy #CryoEM #TRPM8ProteinChannel buff.ly/pSaDTi8
🌱 Can collaboration and innovation shape better science? 🔬 Our Giovanni Maltinti, PhD student in the @GaiaPigino Group, shares why HT and MIND connect scientists and cutting-edge tools like #cryoEM to improve quality of life. Watch the interview 👉 youtube.com/watch?v=CX-fIm…
youtube.com
YouTube
MIND Milano Innovation District
Assess EM model reliability with Q-scores! A new statistical approach applied to EMDB & PDB maps reveals insights into map quality and model fit. Learn more: ow.ly/r0ot50Xngy1 @ucsandiego @ActaCrystD @IUCr #CryoEM #QScores #Validation
Using #cryoEM and functional assays, we showed that MB11 binds to the PDCoV RBD as designed and inhibits viral entry by preventing engagement of the host receptor through steric hindrance, explaining its potent neutralizing activity 11/12
Between frequent manual handling, FIB-milling, and the need to accommodate diverse sample types, grid selection can directly impact the quality of your data View our range of popular & alternative support formats: eu1.hubs.ly/H0tVdjP0 #tomography #CLEM #cryoEM #microscopy
Given that E-FIC is the target of TMPRSS2, we hypothesized that S2′ site-directed antibodies also recognize this state. We thus characterized the complex between SARS-CoV-2 E-FIC and the VN01H1 antibody which neutralizes several human alpha- and beta-CoVs using #cryoEM 10/19
To visualize TMPRSS2-mediated recognition of a coronavirus S2′ site and overcome transient binding, we determined #cryoEM structures of TMPRSS2 bound to the HCoV-NL63 S2′ peptide, providing a blueprint of the interactions that lead to viral entry 9/19
EMS is pleased to announce a series of webinars in cooperation with our colleagues at Quorum, specialists in sample preparation for EM. All webinars are free with registration. Details and registration: hubs.la/Q04dy0Mp0 #EMShasit #emsamplepreparation #cryoem #SEM #FIB
Are you attending the IUCr2026 meeting in Calgary, Canada this August? If so we invite you to stop by our MiTeGen booth (27) to discuss your latest research and to learn how our tools and instruments for #crystallography and #cryoem can accelerate your research - #IUCr2026
How does S. aureus kill cells? @iiscbangalore researchers used #cryoEM to capture the step-by-step assembly of alpha-hemolysin #toxins as they punch pores in red blood cells, revealing how #membrane lipids modulate infection #SARAL #ANRF #ResearchHighlights #ScienceCommunication
How do #bacterial #toxins breach our cells? @iiscbangalore researchers used #cryoEM to reveal step-by-step structural transition of #alphaHL #toxin as it forms pores in lipid membranes, a key process in S. aureus #infections #SARAL #ANRF #ResearchHighlights #ScienceCommunication
Stunning work with Evo 2 generating functional phages — especially the novel protein validated by cryo-EM! At CryoAI Nanomega, we deliver integrated cryo-EM + AI services to accelerate exactly this kind of synthetic biology. #CryoEM #AIinBio
Modifying the bacterial strain led to cleaner bacterial expression of a synthetic BRIL antibody that facilitates protein structure determination via both crystallography and cryo-EM @UniofOxford @ActaCrystF @IUCr #CryoEM #XRayCrystallography #BRIL doi.org/10.1107/S20532…
【#CPHI Japan 出展中｜📍3J-40】 cryo-EMは性能だけで語れるのか？ 100 keVイメージングの検討など、アクセス性・運用性をどう捉えるかが議論されています。 nature.com/articles/d4247… #CryoEM #ElectronMicroscopy
Last week, MB&B hosted Dr. Ryan Feathers (Princeton) for a hands-on workshop on AI for cryo-EM—showcasing cryoDRGN to reveal molecular heterogeneity in challenging datasets. Read more here: bit.ly/3QoEOqq @FeathersRyan #CryoEM #StructuralBiology
For GPCR cryo-EM, the protein is everything, and @NanoimagingS built their entire platform around that reality. Meet our Founding Co-Host → youtu.be/OOo3JSgpn5A Join us April 29th in Boston → ecosystem.drgpcr.com/post/gpcr-happ… #GPCR #CryoEM #StructuralBiology #Boston
CryoJAX is a cryo-EM image-simulation library for building computational data-analysis applications in JAX @harvard @unewhaven @Cornell @ActaCrystD @IUCr #CryoEM #ImageSimulation #AutomaticDifferentiation doi.org/10.1107/S20597…
On the way to #CCPEM 2026 Spring Symposium from London to Nottingham. Excited about the premiere #CryoEM ❄️🔬conference learning, networking, and presenting. @ismb_london and @BirkbeckUoL 🦉will be well represented.
@NYSBC_Science is hosting a @MathforAmerica course on Unveiling Molecular Mysteries: A Journey Into Structural Biology. This course spans 3-parts: April 21 (NMR), May 5 (X-ray crystallography) & May 19 (#cryoEM). Tonight NYSBC’s NMR director, Art Palmer, kicked off the series.
New News & Views in @NatureSMB We highlight how recent #cryoEM work reveals many ligands, pockets & states for #bitter #taste #GPCRs, from intracellular binding to ECL “lids” shaping aftertaste rdcu.be/ferTU Evgenii Ziaikin, Nitsan Dallal
The next #CryoEM Current Practices Webinar speaker will be Miao Zhang from University of Arizona speaking on "Structural basis for the pharmacological modulation of KCa2.2 channels" 4/30/2026 at 12 PM ET / 9AM PT Register for this virtual seminar today: us02web.zoom.us/webinar/regist…
#joboffer #Germany plz spread it I'm hiring a Junior leader (E13; 100% for 3-5 y) to start own independence w/ focus on #CryoEM SPA or ET Ideally 1-2y postdoc experience Plz get in touch, if you are interested in #Structural biology & #MicroBiochem @VAAM_Microbes @GBM_eV
Just an impression of what we're doing.... #joboffer Plz RT & spread words #SelimLab has open positions (#PhD & #postdoc immediately) with focus on #CryoEM structural biology & #cyanobacteria Plz apply if you wanna join an international team #ScienceJobs @RxivJob @jobRxiv
Postdoc Positions - Structural Biology, Biochemistry, Cell Biology University of Cincinnati See the full job description on jobRxiv: jobrxiv.org/job/university… #biochemistry #cellbiology #cryoEM #proteinbiochemistry #structuralbiology #ScienceJobs jobrxiv.org/job/university…
⚛ IOCB Prague has launched state-of-the-art technological equipment for #cryoEM. Tomáš Kouba from @IOCBPrague recently organized a symposium that brought together scientists working in structural biology and emerging technologies.
🧊 An important day for @IOCBPrague and our research: We’ve opened a new underground building at our campus, designed to house a state-of-the-art #cryoEM center with cutting-edge equipment. Congratulations to everyone involved in this multiyear project!
Muñoz-Hernández, Xu, Wieczorek et al. report #cryoEM structures revealing how NEDD1’s C terminus forms an α-helical tetramer that docks onto the γ-TuRC without inducing major conformational changes in the complex during its recruitment to MTOCs hubs.ly/Q03nCNXc0
🔬 We are looking for candidates for two open positions in the Tomáš Kouba Group. The #cryoEM core facility studies 3D structure of proteins and their complexes using single particle analysis. See more on the #IT specialist position ► uochb.cz/en/open-positi… ⤵️ See more on
Kenworthy et al @MedicineUVA explore the evolutionary history of caveolins. Using computational predictions & #CryoEM, the authors show both animal & choanoflagellate caveolins assemble into amphipathic disks composed of seven conserved structural elements hubs.la/Q03BN8r40
How does the metabolic receptor #HCAR1 become activated? Researchers harness #CryoEM to examine HCAR1 unbound and bound to lactate or a synthetic activator and show that the receptor becomes self-activated through rearrangement of extracellular loop 2. scim.ag/4suF99n
New #CryoEM discoveries are decoding the structural properties and evolution of the TSC2 protein complex, which acts as a key brake on the cell growth-promoting #mTORC1 signaling pathway. @lab_manning @HarvardChanSPH Check out the Review: scim.ag/46CKN0J
Researchers cracked the structure of the Hepatitis B Virus surface antigen (HBsAg) using advanced #CryoEM! This discovery reveals how HBsAg assembles into complex filaments and interacts with the capsid to form virions. #InnovativeTsinghua @ScienceMagazine More:
Cryo-EM Structure Illuminates How a Designed Peptide Precisely Pauses the Ribosome sinica.edu.tw/en/news_conten… #CryoEM #Ribosome #eRAP @IBCSinica
Capturing enzymes in motion The structure and dynamics of the ACE enzyme revealed by #CryoEM and molecular simulations. elifesciences.org/articles/10872…
Cryo-EM reveals M. tuberculosis IGPD forms a striking 24-mer assembly with 432 symmetry in both apo and ligand-bound states. Dive into the structural insights: ow.ly/CjzO50XrsJB @ActaCrystF @IUCr #CryoEM #Tuberculosis #HistidineBiosynthesisPathway
Interested in advancing your cellular or structural biology research? Learn more about the new Thermo Scientific Krios 5 Cryo-TEM: buff.ly/PxTmbKK #cellbiology #structuralbiology #cryoEM
Nieng Yan taking a full house of @bmh2024Melb attendees through Nav and Cav channels and their biology in pain toxins and opioids in our StructuralBiology and Biophysics stream #BMH2024 #CryoEM
🚨 PostDoc opportunity at the MRC-LMB 🚨Join our team to explore transcription-coupled splicing using cryoEM and biochemistry! 🔬🧬 Please spread the news 🙏🏼 Apply here: mrc.tal.net/vx/mobile-0/... #Postdoc #CryoEM #MolecularBiology #Cambridge
Microscopy took center stage yesterday at M&M 2025. From nanoscale breakthroughs to cutting-edge cryo-EM tools, plenary speakers Dr. Idrobo and Dr. Carragher lit up the stage. With the Exhibit Hall open, it's time to explore the tech shaping tomorrow! #microscopy #cryoEM
Check out our latest paper about glutaminase filament on @NatureComms! In this paper, we used #CryoEM and light scattering to show that the filament formation of glutaminase is coupled with its activity. nature.com/articles/s4146…
Join us for the #VirtualPub /Correlated Imaging Series with Iban Ubarrechena, Biofisika Institute, @BRforEM, for a talk on "#CryoEM as a magnifying glass into cell biology." All are welcome! 🗓️Fri, Jan 24 @ 13:00 CET Followed by the Tech Exchange. Register⤵️
Pulsed #lasers integrated with #cryoEM: @FitzpatrickLab @ColumbiaBiochem @ZuckermanBrain postdoc Daniel Du aims to boost contrast for near-atomic detail in #cryoET @ChanZuckerberg zuckermaninstitute.columbia.edu/making-world-s… zuckermaninstitute.columbia.edu/science-life-d… elifesciences.org/reviewed-prepr…
The molecular fidelity of Aβ pathology in 5xFAD and AppNL−FPsen1P117L mice revealed by #cryoEM Meinai Song...Deng-Feng Zhang & Qin Cao #amyloid #AlzheimersDisease link.springer.com/article/10.118…
Well done @FarrahBlades on an excellent talk @bmh2024Melb! The streamline #CryoEM data processing pipeline you've set up at @CMMUQ1 using the Bunya supercomputer is helping so many researchers @UQ_News to process data efficiently and answer important biological questions! 👏👏👏
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