#isoforms search results
Cool discussion on #3rdgenseq #isoforms #transcripts #alternativesplicing #genomeassembly #longreads with @ISBSIB @markrobinsonca
ScIsoX: a multidimensional framework for measuring isoform-level transcriptomic complexity in single cells. #SingleCell #scRNAseq #Isoforms @GenomeBiology genomebiology.biomedcentral.com/articles/10.11…
You can do more with MAS-Seq. Understand cell heterogeneity, accurately capture UMIs and identify full-length #isoforms. One MAS-Seq kit comes with reagents to characterize a 3,000 - 10,000 cell single-cell #RNAseq experiment. #PacBio #ASHG22
You can do more with MAS-Seq. Understand cell heterogeneity, accurately capture UMIs and identify full-length #isoforms. One MAS-Seq kit comes with reagents to characterize a 3,000 - 10,000 cell single-cell #RNAseq experiment. #PacBio #ASHG22
Ushijima et al. show a role for #phytochromes in regulation of alternative #promoter usage, resulting in light-dependent protein #isoforms with altered subcellular localization that help the plant respond metabolically to fluctuating light conditions. bit.ly/2iaOFgB
Won one of the poster prizes at the p53/p63/p73 #isoforms conference!!! 🤩🤩 Quite unexpected, as there isn't a lot of data to show. Still happy to know that my scientific discussion skills are improving! Yay 💯 #gradlife #academics
Day 1 at the #RNAUK2022 meeting. Great talks on splicing #isoforms and exciting new #Bioinformaticstools Thanks to the organising committee: @RolandA64475798 @unibirmingham
Sequence full-length #isoforms with greater sensitivity and efficiency than ever before. Introducing ISO-SEQ , the latest technology from GENEWIZ on our new @PacBio® Sequel® platform. Read about it here. hubs.ly/H09rzj_0
A high-resolution #quantitative #proteomics map of post-translational modifications on multiple #isoforms of #Tau reveals the importance of PTMs in #Alzheimer’s #disease. Resource article online now! bit.ly/36xpUDE
“How different are protein #isoforms from the same gene? What isoforms are expressed? How can we study multiple dimensions of isoform function?” Gloria Sheynkman, PhD @GSheynkman of @DanaFarber is sharing her research on #SystemsBiology approaches to study protein isoforms.
Join a session of our live webinar series to learn how the SMART-Seq Pro® Application Kit and ICELL8® cx system facilitate detection of #isoforms, #genefusions, and SNPs with #singlecell #RNAseq. Review the live webinar schedule and register now: ow.ly/A9VM50JenqB
#Isoforms of Fas - one is, one isn't #apoptotic - balanced by an #RNA binding #protein #RBM5 - through #spliceosome buff.ly/2gI0meZ
Generated ~80-100mln reads per @nanopore PromethION flow cell @keygene using @WobbleGenomics normalized cDNA on 🌱 samples. Below you see an image of the effect on 5 most abundant spike-in control transcripts. #isoforms #annotation #raretranscripts
The MAS-Seq method applies the power of #HiFisequencing to single-cell RNA sequencing to identify full-length #isoforms with high accuracy. #PacBio #ASHG22
#p53 #Isoforms and Their Implications in #Cancer by Maximilian Vieler and Suparna Sanyal 👉mdpi.com/2072-6694/10/9… #p53 #p53isoform #cancer
Alternately spliced Musashi protein #isoforms -> Distinct regulatory properties & function #CitedEnsembl @SciReports buff.ly/2wWCtV7
The MAS-Seq method applies the power of #HiFisequencing to single-cell RNA sequencing to identify full-length #isoforms with high accuracy. #PacBio #ASHG22
ScIsoX: a multidimensional framework for measuring isoform-level transcriptomic complexity in single cells. #SingleCell #scRNAseq #Isoforms @GenomeBiology genomebiology.biomedcentral.com/articles/10.11…
N-Terminal deleted isoforms of E3 ligase RNF220 are ubiquitously expressed and required for mouse muscle differentiation doi.org/10.1016/j.moce… #Isoforms #MuscleDifferentiation #Neurodegeneration #RingFingerProtein220 #Variants
Indeed a nice cool study, @syncellbiolab, @anubhav_dhar, @SuchetaDey69384, @MullickSan22454, @Nishaant_PB, @deepak_iisc and Angana. Wonderful to be collaborating with you on this work and looking at #actin #isoforms in #yeast and #mammalian_cells using #UExM.
Preprint: IntAct-U-ExM enables robust, isoform-specific expansion microscopy of actin networks in yeast and mammalian cells. A cool study led by @anubhav_dhar in collab with @Sudiya14 @deepak_iisc #actin biorxiv.org/content/10.110…
Isoform Switching: A Key to Metabolic Flexibility! 🔄 Cells adapt to nutrient changes 🍽️ by regulating isoform usage 🔬, fine-tuning metabolic responses for survival & efficiency ⚖️. #Metabolism #GeneRegulation #Isoforms #Biotech #PrecisionMedicine cell.com/cell-metabolis…
cell.com
Isoform usage as a distinct regulatory layer driving nutrient-responsive metabolic adaptation
Transcriptome modulation is essential for metabolic adaptation to nutrient environments; however, the role of isoform usage is not yet fully understood. Here, Li et al. outline the landscape of...
In this new article we explore TAMA Merge, a powerful tool within #OmicsBox 3.3. that enables researchers to combine novel #isoforms from different conditions into a unified #transcriptome, ensuring even rare isoforms are accurately captured. biobam.com/combining-tran…
A recent @ScholarRock article highlights the value in developing highly-specific antibodies that differentiate between #isoforms and latent forms. Read how their LTBP-49247 #antibody selectively binds & inhibits latent TGF-β1. science.org/doi/10.1126/sc…
Single-cell long-read targeted sequencing reveals transcriptional variation in ovarian cancer. #LongRead @nanopore #RNA #Isoforms #Sequencing #OvarianCancer @NatureComms nature.com/articles/s4146…
nature.com
Single-cell long-read targeted sequencing reveals transcriptional variation in ovarian cancer
Nature Communications - Long-read sequencing allows the detection of RNA isoforms, but is hampered by low throughput and potential artefacts. Here, the authors develop the scTaILoR-seq...
R2Dtool github.com/comprna/R2Dtool for handling, integrating, and viualising isoform-resolved RNA feature data - led by @_AJSethi #bioinformatics #RNA #isoforms academic.oup.com/bioinformatics…
I forgot to add that SCALPEL predictions can be experimentally validated. So, for your next #scRNAseq project, remember to quantify transcript #isoforms! #SCALPEL #singlecell #newtool
🚨 New preprint from the @PlassLab !! Really happy to present #SCALPEL, a fast and easy-to-use tool for isoform quantification at the single-cell level! #scRNAseq #isoforms #singlecell #nextflow @p_cmrc @idibell_cat biorxiv.org/content/10.110…
🚨 New preprint from the @PlassLab !! Really happy to present #SCALPEL, a fast and easy-to-use tool for isoform quantification at the single-cell level! #scRNAseq #isoforms #singlecell #nextflow @p_cmrc @idibell_cat biorxiv.org/content/10.110…
A single human #gene can produce multiple different #RNA and protein molecules, called #isoforms, allowing it to perform multiple functions. Long-read sequencing helps @UKSBCoA researchers identify and measure these RNA isoforms from a single gene across.. rna-seqblog.com/long-read-rna-…
rna-seqblog.com
Long-read RNA sequencing reveals key gene expressions in Alzheimer’s disease
Researchers at the University of Kentucky Sanders-Brown Center on Aging are working to develop a pre-symptomatic disease diagnostic tool for...
Scientists at the @universityofky used a cutting-edge technology called @nanopore #PromethION. This powerful tool allows for the sequencing of long strands of #RNA, providing a detailed picture of the different RNA #isoforms present in each sample. rna-seqblog.com/mapping-medica…
Next week at #nanoporeconf PhD Researcher Sofia Kudasheva will be discussing her work using a combined #sequencing approach to identify novel #isoforms in the study of neurodevelopmental disorders. okt.to/k3mqY2 @nanopore @kudasonya1 @WHaerty
Next month at #nanoporeconf PhD Researcher Sofia Kudasheva will be discussing her work using a combined #sequencing approach to identify novel #isoforms in the study of neurodevelopmental disorders. okt.to/uYJO8v @nanopore @kudasonya1 @WHaerty
Researchers at @WeillCornell performed this massive undertaking in a manner that recorded each individual cell and the long read #RNA sequences it produces. This allowed the researchers to identify #isoforms from hundreds of thousands of individual... rna-seqblog.com/new-atlas-of-m…
Cool discussion on #3rdgenseq #isoforms #transcripts #alternativesplicing #genomeassembly #longreads with @ISBSIB @markrobinsonca
Ushijima et al. show a role for #phytochromes in regulation of alternative #promoter usage, resulting in light-dependent protein #isoforms with altered subcellular localization that help the plant respond metabolically to fluctuating light conditions. bit.ly/2iaOFgB
You can do more with MAS-Seq. Understand cell heterogeneity, accurately capture UMIs and identify full-length #isoforms. One MAS-Seq kit comes with reagents to characterize a 3,000 - 10,000 cell single-cell #RNAseq experiment. #PacBio #ASHG22
ScIsoX: a multidimensional framework for measuring isoform-level transcriptomic complexity in single cells. #SingleCell #scRNAseq #Isoforms @GenomeBiology genomebiology.biomedcentral.com/articles/10.11…
Sequence full-length #isoforms with greater sensitivity and efficiency than ever before. Introducing ISO-SEQ , the latest technology from GENEWIZ on our new @PacBio® Sequel® platform. Read about it here. hubs.ly/H09rzj_0
A high-resolution #quantitative #proteomics map of post-translational modifications on multiple #isoforms of #Tau reveals the importance of PTMs in #Alzheimer’s #disease. Resource article online now! bit.ly/36xpUDE
Join a session of our live webinar series to learn how the SMART-Seq Pro® Application Kit and ICELL8® cx system facilitate detection of #isoforms, #genefusions, and SNPs with #singlecell #RNAseq. Review the live webinar schedule and register now: ow.ly/A9VM50JenqB
Identify & characterise novel #isoforms, novel driver mutations, & #cancer fusion genes with @PacBio #MASSeq Kits! There's still #24hrs⏰ to take advantage of our 50% OFF offer for new users! ➡️Contact Steven for pricing: [email protected] #Genomics #SingleCell
You can do more with MAS-Seq. Understand cell heterogeneity, accurately capture UMIs and identify full-length #isoforms. One MAS-Seq kit comes with reagents to characterize a 3,000 - 10,000 cell single-cell #RNAseq experiment. #PacBio #ASHG22
We're currently offering 50% off @PacBio MAS-Seq Kits for new users! With #MASSeq you can identify & characterise novel #isoforms, novel driver mutations, & #cancer fusion genes. mscience.com.au/view/promotion…
Day 1 at the #RNAUK2022 meeting. Great talks on splicing #isoforms and exciting new #Bioinformaticstools Thanks to the organising committee: @RolandA64475798 @unibirmingham
#Isoforms of Fas - one is, one isn't #apoptotic - balanced by an #RNA binding #protein #RBM5 - through #spliceosome buff.ly/2gHStX9
“How different are protein #isoforms from the same gene? What isoforms are expressed? How can we study multiple dimensions of isoform function?” Gloria Sheynkman, PhD @GSheynkman of @DanaFarber is sharing her research on #SystemsBiology approaches to study protein isoforms.
#Isoforms of Fas - one is, one isn't #apoptotic - balanced by an #RNA binding #protein #RBM5 - through #spliceosome buff.ly/2gI0meZ
A big part of the project was devoted to define the origins of the splicing #isoforms that shape the TAD of NF-YA across vertebrates. 🔎 For example, we found that #sharks probably lost the main alternatively spliced exon of NF-YA (implications on bone formation?) 🦈 (6/8)
The MAS-Seq method applies the power of #HiFisequencing to single-cell RNA sequencing to identify full-length #isoforms with high accuracy. #PacBio #ASHG22
#p53 #Isoforms and Their Implications in #Cancer by Maximilian Vieler and Suparna Sanyal 👉mdpi.com/2072-6694/10/9… #p53 #p53isoform #cancer
The MAS-Seq method applies the power of #HiFisequencing to single-cell RNA sequencing to identify full-length #isoforms with high accuracy. #PacBio #ASHG22
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