#spatialtranscriptomics search results
Standardized metrics for assessment and reproducibility of imaging-based spatial transcriptomics datasets.#SpatialTranscriptomics #StandardizedMetrics #DataRepository #BestPractices #OpenSourceSoftware #Genomics #Bioinformatics @NatureBiotech nature.com/articles/s4158…
#SpatialTranscriptomics Visium @10xGenomics Human Left Atrial Appendage (n=2 donors) & Pulmonary Vein (n=8 donors) Spatial location of #AtrialFibrillation risk genes PITX2 SHOX2 HCN4 @CVpathol 2025 sciencedirect.com/science/articl…
Systematic comparisons among 4 subcellular-resolution #SpatialTranscriptomics methods Stereo-seq v1.3 Visium HD FFPE CosMx 6k Xenium 5k Human Tumors Ground truth CODEX, +scRNAseq Gene detection sensitivity (CosMx performance...🙁) (Spatial) false positives Transcript-protein…
Comparative analysis of commercial Imaging-based #SpatialTranscriptomics methods Xenium CosMx 1k MERSCOPE Tissue Microarray 17 tumors + 16 normal tissues Transcript count Corr. with reference bulk TCGA GTEx RNAseq or scRNAseq Segmentation (Precision Recall F1 score) Accuracy:…
#SpatialTranscriptomics STcompare github.com/JEFworks-Lab/S… Test your gene of interest if it is differentially spatially patterned (r, p, s)🤠 Spatial correlation Spatial fold change Control for spatial autocorrelation Comparisons will be straightforward with Alignment (STalign)…
#SpatialTranscriptomics Visium @10xGenomics Tuberous sclerosis complex-associated Renal Angiomyolipoma (n=1) vs sporadic AML (n=1) vs Renal Cell Carcinoma (n=1) Melanocytic traits in AML MITF MLANA PMEL @RyutaWatanab999 @SciReports 2025 nature.com/articles/s4159…
Congrats to Dr. Savannah LaBuda on being one of the winners of the Young Investigator Poster Award at #AMPath2025! 🎉👏 #SpatialTranscriptomics #GYNpath #MolPath @AMPath @pvhernandezmd @whosainastro
Integrated #pathology annotation on the Xenium platform is now available! See for yourself how easy it is enhance your spatial insights by bridging pathology and #spatialtranscriptomics in a new tutorial. Check it out now: bit.ly/43l7fsX #AMPath2025
Diabetic #T2D db/db 🐭 heart-coronary resistance microvessel multiomics FFPE-scRNAseq #SpatialTranscriptomics Visium @10xGenomics Proteomics Septal Coronary resistance microvessels (how to isolate?😮) Traits of Fatty acid β-oxidation & ketogenesis (Hmgcs2, Acot2) in diabetic…
Comparing single-cell #SpatialTranscriptomics methods on FFPE human tumor #TissueMicroArray CosMx 1k vs MERFISH 500 vs Xenium-UM/-MM 339 93 common genes lung adenocarcinoma pleural mesothelioma Corr. Bulk RNAseq, GeoMx "better F1-scores with Xenium-MM (median, > 75%) than…
CoCo-ST detects global and local biological structures in spatial transcriptomics datasets. #SpatialTranscriptomics #VarianceIdentification @NatureCellBio nature.com/articles/s4155…
"We all love the pretty pictures we get from #SpatialTranscriptomics but the real value lies in the ability to precisely determine the cellular composition & cell-cell relationships - not possible with bulk RNA or even scRNA approaches" 💯% well said @bayraktar_lab! 👏 #FoG2025
STORIES SpatioTemporal Omics eneRgIES Learning Waddington epigenetic (+regulon) landscape from multi-time-point Stereo-seq #SpatialTranscriptomics Potential-based Fused Gromov-Wasserstein #OptimalTransport Linear▶️gene expression error Quadratic▶️spatial consistency @gjhuizing…
Excellent talk from @Sandy_Figiel in @Uroweb #EAUlab session at #EAU25 presenting our cool data (I'm bias!) on #SpatialTranscriptomics & #ClonalAnalysis to detect unique features of metastasing clones in #ProstateCancer. @OxPCaBiol #SPACE_Study #3DLightsheet
Ruochen Dong, @linheng_li lab, gave an outstanding presentation on using #SpatialTranscriptomics to interrogate HSC-niche interaction in the mouse fetal liver at #ISSCR2023. He also received merit and travel awards. Congratulations! @ISSCR
1st single-cell #SpatialTranscriptomics map of human coronary #Atherosclerosis published in peer-reviewed format🤠 CosMx 1k + GeoMx @brukerspatial Immune cell-focused analysis Use CosMx data to deconvolve GeoMx cell composition...😆 @EmboMolMed 2025 embopress.org/doi/full/10.10…
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