#spatialtranscriptomics résultats de recherche
CoCo-ST detects global and local biological structures in spatial transcriptomics datasets. #SpatialTranscriptomics #VarianceIdentification @NatureCellBio nature.com/articles/s4155…
Accurate cell segmentation is integral to #spatialtranscriptomics—that's why we never stop improving ours. Large cells? Tissues with dense nuclei? We’ve got you covered. See how you can segment cells more accurately than ever before: bit.ly/4m1nEcz
Systematic comparisons among 4 subcellular-resolution #SpatialTranscriptomics methods Stereo-seq v1.3 Visium HD FFPE CosMx 6k Xenium 5k Human Tumors Ground truth CODEX, +scRNAseq Gene detection sensitivity (CosMx performance...🙁) (Spatial) false positives Transcript-protein…
🧬 14 spatial clustering methods benchmarked across ~600 #SpatialTranscriptomics datasets 💻 Covering 10 technologies & 8 organs 📊 Reveals how data traits & spatial patterns shape accuracy ⚙️ Recommends optimal preprocessing & method selection 🔗 doi.org/10.1002/imt2.7……
November's #DukeSCIRIP seminar will feature: 1. Xiaohui Jiang of @DukeBiostats on 'X-bridge' for #SingleCell and spatial panel analysis 2. Dr. Ru-Rong Ji of @DukeMedSchool on #SpatialTranscriptomics of #SensoryNeurons 11/5 12-1pm in MSRBIII or online dmpi.duke.edu/duke-single-ce…
#WernerSyndrome hiPSC-derived engineered vessel #SpatialTranscriptomics #Visium @10xGenomics + #Metabolomics▶️ #BranchedChainKetoAcid⬇️ #MonohydroxyFattyAcid⬆️ in Werner vessels with traits of #PrematureAging Aligned #SmoothMuscleCell in Collagen hydrogel➡️ Roll-up around φ…
#SpatialTranscriptomics 🐭#Stroke #Visium @10xGenomics #Photothrombosis 3 dpi Stroke▶️ ⏫Microglia/Macrophage Galectin-1/3/9➡️ Astrocyte/Oligodendrocyte CD44 at peri-infarct zone▶️ ⏫remyelination ⏫neurobehavioral performance Post-stroke benefits of LGALS9-expressing…
#SpatialTranscriptomics Visium #CerebralMalaria 🐭+P.berghei ANKA -/+Artesunate Malaria infection▶️ ⏫🧠#EndothelialCell, immune cells SPATA spatial trajectory inference of EC-rich spots in infected🧠▶️ ⏫EC antigen processing/presentation + leukocyte adhesion ⏬BBB Partially…
How do we uncover cell-cell interactions from #SpatialTranscriptomics data? Excited to share Niche-DE (doi.org/10.1186/s13059…). Niche-DE asks how does a cell’s transcriptome depend on its spatial neighbors, by identifying Niche-Differentially Expressed genes. 1/9
Comparing single-cell #SpatialTranscriptomics methods on FFPE human tumor #TissueMicroArray CosMx 1k vs MERFISH 500 vs Xenium-UM/-MM 339 93 common genes lung adenocarcinoma pleural mesothelioma Corr. Bulk RNAseq, GeoMx "better F1-scores with Xenium-MM (median, > 75%) than…
"We all love the pretty pictures we get from #SpatialTranscriptomics but the real value lies in the ability to precisely determine the cellular composition & cell-cell relationships - not possible with bulk RNA or even scRNA approaches" 💯% well said @bayraktar_lab! 👏 #FoG2025
⚡️Exciting Breakthrough in Progressive Multiple Sclerosis⚡️ Much humbled to contribute to this exciting project from @Pluchinolab . Analysing 200+ sections from 50+ patients, showcases the power of #spatialtranscriptomics in rare cell localization. 🧠 @IBT_CAS @LukasValihrach
Proud to see our work out in @NeuroCellPress ! cell.com/neuron/fulltex… With Bongsoo Park, Dimitris Tsitsipatis @DanielZucha @LukasValihrach @irina_mohorianu @Pluchinolab @BeermanHSCaging !
🚨 Exciting Opportunity! 🚨 @OhioStatePIIO + @OSUWexMed Pathology are recruiting a Tenure-Track Faculty in Spatial Immuno-Oncology Research 🧬🔬 Lead cutting-edge work in #SpatialTranscriptomics, #SpatialProteomics & #ImmunoOncology to decode the #TumorMicroenvironment.…
#SpatialOmics #ImagingMassSpec #SpatialTranscriptomics MISTy Multiview Intercellular SpaTial modeling framework bioconductor.org/packages/relea… View/spatial scale-specific feature interactions Intraview - same location (intra-to-multicellulat) Juxtaview - immediate neighborhood…
Systematic benchmarking of computational methods to identify spatially variable genes. #SpatialTranscriptomics #MethodsBenchmarking @GenomeBiology genomebiology.biomedcentral.com/articles/10.11…
GOD IS GOOD! Today, I passed my #PhD Dissertation Defense!!! 🎉 Thank you to everyone who believed in me. Thank you to all my mentors, friends, and family. 🥰 I would not be where I am today without all of you. 🙏❤️ @SBS_UNTHSC #SpatialTranscriptomics #DoubleDocs @A_P_S_A
Excellent talk from @Sandy_Figiel in @Uroweb #EAUlab session at #EAU25 presenting our cool data (I'm bias!) on #SpatialTranscriptomics & #ClonalAnalysis to detect unique features of metastasing clones in #ProstateCancer. @OxPCaBiol #SPACE_Study #3DLightsheet
Reminder: Join us 10/30 for the @Labroots webinar: From Myelin Damage to Immune Dysfunction: Unravelling the Aging Brain Updated times: 6 am PDT | 9 am EDT | 2 pm CET | 9 pm SGT Register: hubs.ly/Q03QL0h20 #SpatialTranscriptomics #Neurobiology #SpatialBiology
Systematic comparisons among 4 subcellular-resolution #SpatialTranscriptomics methods Stereo-seq v1.3 Visium HD FFPE CosMx 6k Xenium 5k Human Tumors Ground truth CODEX, +scRNAseq Gene detection sensitivity (CosMx performance...🙁) (Spatial) false positives Transcript-protein…
I'm excited to present my first postdoctoral research project: FineST⭐[GitHub:github.com/StatBiomed/Fin…]. Welcome to join and discuss! Your valuable feedback would be greatly appreciated. 🤝 #SpatialTranscriptomics #TumorMicroenvironment #Bioinformatics #CellCommunication
Visium HD or Xenium Prime 5K? Two paths to spatial insights—one for broad, unbiased discovery, the other for targeted, cell-level precision. Read how each fits discovery and validation workflows: signiosbio.com/blog/10x-visiu… #SpatialBiology #SingleCell #SpatialTranscriptomics
signiosbio.com
10x Visium HD vs. Xenium Prime | Advanced Deep Dive
Compare 10x Genomics Visium HD and Xenium Prime 5K for spatial transcriptomics. Explore chemistry, resolution, FFPE compatibility, and application fit for discovery vs targeted research. Advanced...
Excited to share the fresh STOmics Newsletter (Aug–Sep 2025)! 🎉 220+ Stereo-seq breakthroughs, Alzheimer’s atlas, event recaps & how-to videos—all in one click. Read & retweet! 👉bit.ly/4o0AdXt #STOmics #StereoSeq #SpatialTranscriptomics
🦠💩 #Microbiome 🧬🔬 #SpatialTranscriptomics 🤖🗣️🤖 #ArtificialIntelligence Agents for #PrecisionMedicine & #ColorectalCancer Research 💉 Proud of our #VelazquezVillarrealLab team for presenting TWO outstanding posters on 🎉 2025 @cityofhope Annual Poster Session @PECGSnetwork
November's #DukeSCIRIP seminar will feature: 1. Xiaohui Jiang of @DukeBiostats on 'X-bridge' for #SingleCell and spatial panel analysis 2. Dr. Ru-Rong Ji of @DukeMedSchool on #SpatialTranscriptomics of #SensoryNeurons 11/5 12-1pm in MSRBIII or online dmpi.duke.edu/duke-single-ce…
🧬 14 spatial clustering methods benchmarked across ~600 #SpatialTranscriptomics datasets 💻 Covering 10 technologies & 8 organs 📊 Reveals how data traits & spatial patterns shape accuracy ⚙️ Recommends optimal preprocessing & method selection 🔗 doi.org/10.1002/imt2.7……
CoCo-ST detects global and local biological structures in spatial transcriptomics datasets. #SpatialTranscriptomics #VarianceIdentification @NatureCellBio nature.com/articles/s4155…
Wrapping up an incredible week at #AGTA2025! Grateful to everyone who dropped by our booth. Big thanks to Damian for his talk on the world-first @ParseBio experiment in human malaria–infected spleen samples. #Genomics #SpatialTranscriptomics #EnablingDiscovery
New in the October 15 issue from the Cancer Research special series— From Harmony to Discord: Multicellular Coordination in Tissues and Its Rewiring in Cancer doi.org/10.1158/0008-5… @drmervedede @kchenken @MDAndersonNews #SingleCellTranscriptomics #SpatialTranscriptomics
#SpatialOmics #ImagingMassSpec #SpatialTranscriptomics MISTy Multiview Intercellular SpaTial modeling framework bioconductor.org/packages/relea… View/spatial scale-specific feature interactions Intraview - same location (intra-to-multicellulat) Juxtaview - immediate neighborhood…
⚡️Exciting Breakthrough in Progressive Multiple Sclerosis⚡️ Much humbled to contribute to this exciting project from @Pluchinolab . Analysing 200+ sections from 50+ patients, showcases the power of #spatialtranscriptomics in rare cell localization. 🧠 @IBT_CAS @LukasValihrach
Proud to see our work out in @NeuroCellPress ! cell.com/neuron/fulltex… With Bongsoo Park, Dimitris Tsitsipatis @DanielZucha @LukasValihrach @irina_mohorianu @Pluchinolab @BeermanHSCaging !
ChatGPT-Like AI Model Details 1,300 Regions/Subregions in Mouse Brain Map Tissue-agnostic CellTransformer can be used on other organs and tissues, including cancerous tissue, for which large-scale #spatialtranscriptomics data is available @UCSF #brain #AI hubs.li/Q03MQQXq0
CoCo-ST detects global and local biological structures in spatial transcriptomics datasets. #SpatialTranscriptomics #VarianceIdentification @NatureCellBio nature.com/articles/s4155…
🚨New #SpatialTranscriptomics #Bioinformatics data resource out in @naturemethods. SODB, a platform with >2,400 manually curated spatial experiments from >25 spatial omics technologies & interactive analytical modules. This🧵will walk you through all the features of SODB [1/33]
Ruochen Dong, @linheng_li lab, gave an outstanding presentation on using #SpatialTranscriptomics to interrogate HSC-niche interaction in the mouse fetal liver at #ISSCR2023. He also received merit and travel awards. Congratulations! @ISSCR
Accurate cell segmentation is integral to #spatialtranscriptomics—that's why we never stop improving ours. Large cells? Tissues with dense nuclei? We’ve got you covered. See how you can segment cells more accurately than ever before: bit.ly/4m1nEcz
How do we uncover cell-cell interactions from #SpatialTranscriptomics data? Excited to share Niche-DE (doi.org/10.1186/s13059…). Niche-DE asks how does a cell’s transcriptome depend on its spatial neighbors, by identifying Niche-Differentially Expressed genes. 1/9
We’re all wondering what the future of #spatialtranscriptomics (ST) has in store. Well, I think the near future will look a lot like the new 6000-plex dataset reviewed here (link to the original source at the end of this post). SAMPLE An entire 100 mm² intact 5 µm FFPE section…
Systematic comparisons among 4 subcellular-resolution #SpatialTranscriptomics methods Stereo-seq v1.3 Visium HD FFPE CosMx 6k Xenium 5k Human Tumors Ground truth CODEX, +scRNAseq Gene detection sensitivity (CosMx performance...🙁) (Spatial) false positives Transcript-protein…
#SpatialTranscriptomics 🐭#Stroke #Visium @10xGenomics #Photothrombosis 3 dpi Stroke▶️ ⏫Microglia/Macrophage Galectin-1/3/9➡️ Astrocyte/Oligodendrocyte CD44 at peri-infarct zone▶️ ⏫remyelination ⏫neurobehavioral performance Post-stroke benefits of LGALS9-expressing…
Excited to share our #SingleCell and #SpatialTranscriptomics analysis of #ExerciseTraining remodeling of #WhiteAdiposeTissue through innervation, vascularization, and #ExtracellularMatrix in mouse and human with #LaurieGoodyear #JanWillemMiddelbeek @PasqualeNigro9 @MVamvini…
🧬 14 spatial clustering methods benchmarked across ~600 #SpatialTranscriptomics datasets 💻 Covering 10 technologies & 8 organs 📊 Reveals how data traits & spatial patterns shape accuracy ⚙️ Recommends optimal preprocessing & method selection 🔗 doi.org/10.1002/imt2.7……
We are very very VERY excited to be running #cosmx #singlecell #spatialtranscriptomics experiments in @UofGlasgow @UofGCancerSci @UofGMVLS Well done to the @LabSpatialNBJ team @nanostringtech
#WernerSyndrome hiPSC-derived engineered vessel #SpatialTranscriptomics #Visium @10xGenomics + #Metabolomics▶️ #BranchedChainKetoAcid⬇️ #MonohydroxyFattyAcid⬆️ in Werner vessels with traits of #PrematureAging Aligned #SmoothMuscleCell in Collagen hydrogel➡️ Roll-up around φ…
Excellent talk from @Sandy_Figiel in @Uroweb #EAUlab session at #EAU25 presenting our cool data (I'm bias!) on #SpatialTranscriptomics & #ClonalAnalysis to detect unique features of metastasing clones in #ProstateCancer. @OxPCaBiol #SPACE_Study #3DLightsheet
GOD IS GOOD! Today, I passed my #PhD Dissertation Defense!!! 🎉 Thank you to everyone who believed in me. Thank you to all my mentors, friends, and family. 🥰 I would not be where I am today without all of you. 🙏❤️ @SBS_UNTHSC #SpatialTranscriptomics #DoubleDocs @A_P_S_A
🔬 A new computational approach pioneered by researchers at the @broadinstitute eliminates time-intensive imaging, enabling high-resolution spatial mapping of gene expression in tissue. See how they're making #SpatialTranscriptomics easier for everyone: bit.ly/3G9Hrau
Comparing single-cell #SpatialTranscriptomics methods on FFPE human tumor #TissueMicroArray CosMx 1k vs MERFISH 500 vs Xenium-UM/-MM 339 93 common genes lung adenocarcinoma pleural mesothelioma Corr. Bulk RNAseq, GeoMx "better F1-scores with Xenium-MM (median, > 75%) than…
Wow, this is big! Congrats to all authors!👏 👉 Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer's Disease 👉 biorxiv.org/content/10.110… #SpatialTranscriptomics #Visium #snRNAseq #ParseBiosciences
Our work on spatial multiomics in Alzheimer’s disease and Down syndrome now on bioRxiv biorxiv.org/content/10.110…
Pleased to share our latest #SpatialTranscriptomics output now on @biorxivpreprint We show marked variation in gene expr relating to @Decipher_VCYT, #Oncotype_DX & #ProstaDiag genomic scores Being presented by @Sandy_Figiel this afternoon #EAU23!! biorxiv.org/content/10.110…
#SpatialTranscriptomics #ParkinsonsDisease A role of #FGF9 in Glia #Ferroptosis in PD?😁 #Visium @10xGenomics +snRNAseq MPTP🐭 #SubstantiaNigra FGF9 ⏬in PD Neuron ⏫in PD Ependymal cell FGF9-to-FGFR1/2/3 (CellChat, likely Neuron-to-Oligodendrocyte/Astrocyte) ⏬in PD…
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