#spatialtranscriptomics результаты поиска
CoCo-ST detects global and local biological structures in spatial transcriptomics datasets. #SpatialTranscriptomics #VarianceIdentification @NatureCellBio nature.com/articles/s4155…
Systematic comparisons among 4 subcellular-resolution #SpatialTranscriptomics methods Stereo-seq v1.3 Visium HD FFPE CosMx 6k Xenium 5k Human Tumors Ground truth CODEX, +scRNAseq Gene detection sensitivity (CosMx performance...🙁) (Spatial) false positives Transcript-protein…
Systematic benchmarking of computational methods to identify spatially variable genes. #SpatialTranscriptomics #MethodsBenchmarking @GenomeBiology genomebiology.biomedcentral.com/articles/10.11…
Accurate cell segmentation is integral to #spatialtranscriptomics—that's why we never stop improving ours. Large cells? Tissues with dense nuclei? We’ve got you covered. See how you can segment cells more accurately than ever before: bit.ly/4m1nEcz
"We all love the pretty pictures we get from #SpatialTranscriptomics but the real value lies in the ability to precisely determine the cellular composition & cell-cell relationships - not possible with bulk RNA or even scRNA approaches" 💯% well said @bayraktar_lab! 👏 #FoG2025
#SpatialTranscriptomics #BrainOrganoid #Glioblastoma Striatal implant of Brain organoids +Mutant TERT p.C228T TP53 R248Q➡️SOX11+ Proneural GBM subtype +Mutant TERT p.C228T PTENΔ NF1Δ➡️ERBB3+ Mesenchymal GBM subtype In-depth single-cell spatial transcriptional & CNV landscape…
#SpatialTranscriptomics Visium #CerebralMalaria 🐭+P.berghei ANKA -/+Artesunate Malaria infection▶️ ⏫🧠#EndothelialCell, immune cells SPATA spatial trajectory inference of EC-rich spots in infected🧠▶️ ⏫EC antigen processing/presentation + leukocyte adhesion ⏬BBB Partially…
🧬 14 spatial clustering methods benchmarked across ~600 #SpatialTranscriptomics datasets 💻 Covering 10 technologies & 8 organs 📊 Reveals how data traits & spatial patterns shape accuracy ⚙️ Recommends optimal preprocessing & method selection 🔗 doi.org/10.1002/imt2.7……
#WernerSyndrome hiPSC-derived engineered vessel #SpatialTranscriptomics #Visium @10xGenomics + #Metabolomics▶️ #BranchedChainKetoAcid⬇️ #MonohydroxyFattyAcid⬆️ in Werner vessels with traits of #PrematureAging Aligned #SmoothMuscleCell in Collagen hydrogel➡️ Roll-up around φ…
Comparing single-cell #SpatialTranscriptomics methods on FFPE human tumor #TissueMicroArray CosMx 1k vs MERFISH 500 vs Xenium-UM/-MM 339 93 common genes lung adenocarcinoma pleural mesothelioma Corr. Bulk RNAseq, GeoMx "better F1-scores with Xenium-MM (median, > 75%) than…
CODA integrative CrOss-sample alignment and spatially Differential gene Analysis for #SpatialTranscriptomics Global rigid alignment➡️ Shared coordinate grid embedding➡️ 3-channel image representation➡️ LightGlue common domain identification➡️ Local nonlinear alignment Work with…
🚨 Exciting Opportunity! 🚨 @OhioStatePIIO + @OSUWexMed Pathology are recruiting a Tenure-Track Faculty in Spatial Immuno-Oncology Research 🧬🔬 Lead cutting-edge work in #SpatialTranscriptomics, #SpatialProteomics & #ImmunoOncology to decode the #TumorMicroenvironment.…
November's #DukeSCIRIP seminar will feature: 1. Xiaohui Jiang of @DukeBiostats on 'X-bridge' for #SingleCell and spatial panel analysis 2. Dr. Ru-Rong Ji of @DukeMedSchool on #SpatialTranscriptomics of #SensoryNeurons 11/5 12-1pm in MSRBIII or online dmpi.duke.edu/duke-single-ce…
#SpatialTranscriptomics 🐭#Stroke #Visium @10xGenomics #Photothrombosis 3 dpi Stroke▶️ ⏫Microglia/Macrophage Galectin-1/3/9➡️ Astrocyte/Oligodendrocyte CD44 at peri-infarct zone▶️ ⏫remyelination ⏫neurobehavioral performance Post-stroke benefits of LGALS9-expressing…
Myocilin marks the glia limitans superficialis Astrocyte Re-analysis of brain-wide #SpatialTranscriptomics & sc-/sn-RNAseq data➡️ Myoc+ 2% of total astrocytes that cover brain/spinal cord surface and extend processes into parenchyma Any marker for glia limitans perivascularis…
STORIES SpatioTemporal Omics eneRgIES Learning Waddington epigenetic (+regulon) landscape from multi-time-point Stereo-seq #SpatialTranscriptomics Potential-based Fused Gromov-Wasserstein #OptimalTransport Linear▶️gene expression error Quadratic▶️spatial consistency @gjhuizing…
How do we uncover cell-cell interactions from #SpatialTranscriptomics data? Excited to share Niche-DE (doi.org/10.1186/s13059…). Niche-DE asks how does a cell’s transcriptome depend on its spatial neighbors, by identifying Niche-Differentially Expressed genes. 1/9
Systematic comparisons among 4 subcellular-resolution #SpatialTranscriptomics methods Stereo-seq v1.3 Visium HD FFPE CosMx 6k Xenium 5k Human Tumors Ground truth CODEX, +scRNAseq Gene detection sensitivity (CosMx performance...🙁) (Spatial) false positives Transcript-protein…
I'm excited to present my first postdoctoral research project: FineST⭐[GitHub:github.com/StatBiomed/Fin…]. Welcome to join and discuss! Your valuable feedback would be greatly appreciated. 🤝 #SpatialTranscriptomics #TumorMicroenvironment #Bioinformatics #CellCommunication
Visium HD or Xenium Prime 5K? Two paths to spatial insights—one for broad, unbiased discovery, the other for targeted, cell-level precision. Read how each fits discovery and validation workflows: signiosbio.com/blog/10x-visiu… #SpatialBiology #SingleCell #SpatialTranscriptomics
Excited to share the fresh STOmics Newsletter (Aug–Sep 2025)! 🎉 220+ Stereo-seq breakthroughs, Alzheimer’s atlas, event recaps & how-to videos—all in one click. Read & retweet! 👉bit.ly/4o0AdXt #STOmics #StereoSeq #SpatialTranscriptomics
🦠💩 #Microbiome 🧬🔬 #SpatialTranscriptomics 🤖🗣️🤖 #ArtificialIntelligence Agents for #PrecisionMedicine & #ColorectalCancer Research 💉 Proud of our #VelazquezVillarrealLab team for presenting TWO outstanding posters on 🎉 2025 @cityofhope Annual Poster Session @PECGSnetwork
November's #DukeSCIRIP seminar will feature: 1. Xiaohui Jiang of @DukeBiostats on 'X-bridge' for #SingleCell and spatial panel analysis 2. Dr. Ru-Rong Ji of @DukeMedSchool on #SpatialTranscriptomics of #SensoryNeurons 11/5 12-1pm in MSRBIII or online dmpi.duke.edu/duke-single-ce…
🧬 14 spatial clustering methods benchmarked across ~600 #SpatialTranscriptomics datasets 💻 Covering 10 technologies & 8 organs 📊 Reveals how data traits & spatial patterns shape accuracy ⚙️ Recommends optimal preprocessing & method selection 🔗 doi.org/10.1002/imt2.7……
CoCo-ST detects global and local biological structures in spatial transcriptomics datasets. #SpatialTranscriptomics #VarianceIdentification @NatureCellBio nature.com/articles/s4155…
Systematic comparisons among 4 subcellular-resolution #SpatialTranscriptomics methods Stereo-seq v1.3 Visium HD FFPE CosMx 6k Xenium 5k Human Tumors Ground truth CODEX, +scRNAseq Gene detection sensitivity (CosMx performance...🙁) (Spatial) false positives Transcript-protein…
"We all love the pretty pictures we get from #SpatialTranscriptomics but the real value lies in the ability to precisely determine the cellular composition & cell-cell relationships - not possible with bulk RNA or even scRNA approaches" 💯% well said @bayraktar_lab! 👏 #FoG2025
🚨New #SpatialTranscriptomics #Bioinformatics data resource out in @naturemethods. SODB, a platform with >2,400 manually curated spatial experiments from >25 spatial omics technologies & interactive analytical modules. This🧵will walk you through all the features of SODB [1/33]
Accurate cell segmentation is integral to #spatialtranscriptomics—that's why we never stop improving ours. Large cells? Tissues with dense nuclei? We’ve got you covered. See how you can segment cells more accurately than ever before: bit.ly/4m1nEcz
We’re all wondering what the future of #spatialtranscriptomics (ST) has in store. Well, I think the near future will look a lot like the new 6000-plex dataset reviewed here (link to the original source at the end of this post). SAMPLE An entire 100 mm² intact 5 µm FFPE section…
Ruochen Dong, @linheng_li lab, gave an outstanding presentation on using #SpatialTranscriptomics to interrogate HSC-niche interaction in the mouse fetal liver at #ISSCR2023. He also received merit and travel awards. Congratulations! @ISSCR
How do we uncover cell-cell interactions from #SpatialTranscriptomics data? Excited to share Niche-DE (doi.org/10.1186/s13059…). Niche-DE asks how does a cell’s transcriptome depend on its spatial neighbors, by identifying Niche-Differentially Expressed genes. 1/9
🧬 14 spatial clustering methods benchmarked across ~600 #SpatialTranscriptomics datasets 💻 Covering 10 technologies & 8 organs 📊 Reveals how data traits & spatial patterns shape accuracy ⚙️ Recommends optimal preprocessing & method selection 🔗 doi.org/10.1002/imt2.7……
Excited to share our #SingleCell and #SpatialTranscriptomics analysis of #ExerciseTraining remodeling of #WhiteAdiposeTissue through innervation, vascularization, and #ExtracellularMatrix in mouse and human with #LaurieGoodyear #JanWillemMiddelbeek @PasqualeNigro9 @MVamvini…
Comparing single-cell #SpatialTranscriptomics methods on FFPE human tumor #TissueMicroArray CosMx 1k vs MERFISH 500 vs Xenium-UM/-MM 339 93 common genes lung adenocarcinoma pleural mesothelioma Corr. Bulk RNAseq, GeoMx "better F1-scores with Xenium-MM (median, > 75%) than…
#SpatialTranscriptomics 🐭#Stroke #Visium @10xGenomics #Photothrombosis 3 dpi Stroke▶️ ⏫Microglia/Macrophage Galectin-1/3/9➡️ Astrocyte/Oligodendrocyte CD44 at peri-infarct zone▶️ ⏫remyelination ⏫neurobehavioral performance Post-stroke benefits of LGALS9-expressing…
GOD IS GOOD! Today, I passed my #PhD Dissertation Defense!!! 🎉 Thank you to everyone who believed in me. Thank you to all my mentors, friends, and family. 🥰 I would not be where I am today without all of you. 🙏❤️ @SBS_UNTHSC #SpatialTranscriptomics #DoubleDocs @A_P_S_A
We are very very VERY excited to be running #cosmx #singlecell #spatialtranscriptomics experiments in @UofGlasgow @UofGCancerSci @UofGMVLS Well done to the @LabSpatialNBJ team @nanostringtech
Wow, this is big! Congrats to all authors!👏 👉 Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer's Disease 👉 biorxiv.org/content/10.110… #SpatialTranscriptomics #Visium #snRNAseq #ParseBiosciences
Our work on spatial multiomics in Alzheimer’s disease and Down syndrome now on bioRxiv biorxiv.org/content/10.110…
Excellent talk from @Sandy_Figiel in @Uroweb #EAUlab session at #EAU25 presenting our cool data (I'm bias!) on #SpatialTranscriptomics & #ClonalAnalysis to detect unique features of metastasing clones in #ProstateCancer. @OxPCaBiol #SPACE_Study #3DLightsheet
🔬 A new computational approach pioneered by researchers at the @broadinstitute eliminates time-intensive imaging, enabling high-resolution spatial mapping of gene expression in tissue. See how they're making #SpatialTranscriptomics easier for everyone: bit.ly/3G9Hrau
#SpatialTranscriptomics #ParkinsonsDisease A role of #FGF9 in Glia #Ferroptosis in PD?😁 #Visium @10xGenomics +snRNAseq MPTP🐭 #SubstantiaNigra FGF9 ⏬in PD Neuron ⏫in PD Ependymal cell FGF9-to-FGFR1/2/3 (CellChat, likely Neuron-to-Oligodendrocyte/Astrocyte) ⏬in PD…
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