Subhojit Roy, MD, PhD
@Roy_Lab_Thinks
Science. Music. Sometimes funny. https://www.youtube.com/channel/UCd_bJwirwOnBeTb8K-t0xyA
You might like
Massive 10+ year effort in lab spearheaded by @leonardoaparrar and Kayal (secret account 🤔). Unreal cover by @EmmaVIDALL that says it all.
2023's final issue is out! cell.com/neuron/current Cover story is from @Roy_Lab_Thinks's lab revealing an unexpected physiologic role for α-synuclein phosphorylation in clustering synaptic vesicles and restricting neurotransmitter release. Read it here cell.com/neuron/fulltex…
Last ditch experiments before starting new journey!
Signs of new life amidst carnage. Postdoc Leo @leonardoaparrar (left, Brent on right) is heading East to U Maryland @UMmedschool as an Asst Professor with the Institute for Neuroscience Discovery (medschool.umaryland.edu/um-mind/)
Transformative medical discoveries from utterly basic science is not an exception. Its the rule. nature.com/articles/d4158…
Check out our new resource paper @CellStemCell, where we present a brain organoid atlas of human neurodevelopmental disorders. Surprising was that nearly all patients had abnormal organoids. The challenge was aligning defects to clinical. authors.elsevier.com/a/1m2L96tu0Ctj…
Scientists are obsessed with intelligence. But you don't need an astronomical IQ to design a simple experiment that will slash through the darkness. In fact high IQ people often lack the simple-minded clarity needed for designing good experiments.
...but as G. Costanza would say: is this "Significant Shrinkage"?
Neurons transmit signals through synaptic vesicle release, but the nanoscale dynamics of this process have been unclear. In a new Science study, researchers report using time-resolved cryo–electron tomography to visualize synaptic vesicle dynamics in situ and propose a unified…
Incredible by @OdedRechavi ... an AI thingy-bop that reviews your manuscript with a very high bar and takes no prisoners. But you can do this in your pajamas and no one gets to see it. Takes a while but once you get the results you'll know why: qedscience.com
qedscience.com
q.e.d Science
Critical Thinking AI for constructive criticism and science evaluation
"Even short, regular check-ins can make a difference. Time spent helping students to solve problems, or simply asking how a project is going, will pay dividends. It also saves time later by catching small problems before they become big ones" nature.com/articles/d4158…
🚨New in Lancet Neurology: Autopsy study of aducanumab in #Alzheimer’s shows superficial cortical Aβ cleared, but deeper persists. ARIA showed inflammation+ microinfarcts in leptomeningeal/penetrating vessels. Some path is PET-invisible. @DrNeuroChic authors.elsevier.com/a/1lxn85FFzL...
Thank you John Sayer @johnasayer for sharing your experience of fee-free #OA publishing in @J_Cell_Sci via our #ReadAndPublish agreement with @Uni_Newcastle @uonlib Read John’s paper bit.ly/4q8NMFC Is your institution participating? bit.ly/3O7BxGi
4 Nobels for UC in 2025, 75 since 1934, 1/4 winning women have ties to a UC. universityofcalifornia.edu/news/uc-wins-5…
I'm giving a talk at this SFN sponsored symposium in Singapore, students in the area consider submitting abstract - deadline coming up Oct 14: sfn.sg/sfn-sg-annual-…
Honestly if I was a non human primate, I'm not sure I'd appreciate a human just sitting and staring at me all day. #justsa
I went to #Chile 25 years ago - when Internet wasn't a thing - and this is all I needed to know. It went just fine.
“She took a character on the page and gave her such truth, precision and warmth that Hyacinth became part of the national conversation; instantly recognisable, endlessly quotable, and loved around the world" theguardian.com/tv-and-radio/2…
"So far, just the headline findings have been released. Scientists say the full study needs to be published and assessed by independent experts to properly assess what has been achieved" Umm...yes. bbc.com/news/articles/…
"But the foibles and embellishments that make up his story have no place in modern cricket - rubber snakes, mobile phones, firecrackers et al - all of which would today attract ICC demerit points, rather than foster sense of enjoying the stage together" espncricinfo.com/story/dickie-b…
Slowly getting ready to finally submit this paper. Would love feedback. In essence, we mapped and tracked EV transfer of a-synuclein single molecules from neurons to neurons. @Roy_Lab_Thinks @christlet biorxiv.org/content/10.110…
Target engagement + "increased myelination (P = 0.0137) and improved MSEL developmental outcomes (P = 0.0171). Thus, interim results suggest that gene therapy with MYR-101 is well tolerated and shows early effects in Canavan's Disease" AAVs in oligos! nature.com/articles/s4159…
Our new preprint is up! This is the main postdoc work of Theresa Wiesner, focusing on exocytosis along the axon shaft and its regulation by the submembrane actin-spectrin scaffold: biorxiv.org/content/10.110… Read the thread below for a summary of our findings 🧵1/11
United States Trends
- 1. yeonjun 254K posts
- 2. #CARTMANCOIN 1,939 posts
- 3. Broncos 67.5K posts
- 4. Raiders 66.6K posts
- 5. $APDN $0.20 Applied DNA N/A
- 6. Bo Nix 18.5K posts
- 7. Geno 19.1K posts
- 8. $LMT $450.50 Lockheed F-35 N/A
- 9. $SENS $0.70 Senseonics CGM N/A
- 10. #iQIYIiJOYTH2026 1.05M posts
- 11. daniela 53.8K posts
- 12. Sean Payton 4,862 posts
- 13. #criticalrolespoilers 5,172 posts
- 14. Kehlani 11.1K posts
- 15. Danny Brown 3,244 posts
- 16. #TNFonPrime 4,080 posts
- 17. #PowerForce 1,048 posts
- 18. Kenny Pickett 1,523 posts
- 19. Chip Kelly 2,020 posts
- 20. MIND-BLOWING 21.9K posts
You might like
-
Tanentzapf Lab
@TanentzapfLab -
beth stevens
@stevens1lab -
Meng-meng Fu
@Meng2Fu -
Bartolini Lab
@BartoliniLab -
Ricardo Henriques
@HenriquesLab -
Prachee Avasthi
@PracheeAC -
Christophe Leterrier
@christlet -
Uri Manor 💔
@manorlaboratory -
Fred Meunier
@MeunierLab -
Jason Shepherd
@JasonSynaptic -
Andy Moore
@aaandmoore -
Ewerslab
@ewers_helge -
Tim Mosca (he/him)
@drosophilosophy -
A/Prof Samantha Stehbens PhD
@SamStehbens -
Iain Cheeseman
@iaincheeseman
Something went wrong.
Something went wrong.