Ling’s Cell Physiology
@aihtheory
To honor Dr. Gilbert Ling (1919–2019) for his contributions to cell physiology based on applied quantum mechanics (physical organic chemistry).
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To slow aging, one must preserve coherence by sustaining Mg²⁺-ATP sufficiency, auxiliary Ca²⁺ regulation, and intracellular K⁺ sufficiency to protect structured water dynamics.
Law of Aging (via AIH Principle) Aging is the progressive loss of cellular coherence — the ordered state of proteins, water, and ions maintained by Mg²⁺-ATP as the cardinal adsorbent and Ca²⁺ as its auxiliary adsorbent.
T3 × Mg²⁺ × K⁺ Interaction •T3 sufficiency → ↑ Mg²⁺-ATP → protects retina from oxidative stress •T3 deficiency + low Mg²⁺ → ↓ ATP → eyelid twitching + visual instability •T3 sufficiency → ↑ intracellular K⁺ retention → supports tear gland secretion •T3…
“I would rather have questions that can’t be answered than answers that can’t be questioned.” - Richard Feynman Question everything & everyone! m.youtube.com/watch?v=RLONpD…
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Force Your Brain to Think Like a Genius | Richard Feynman
“Education can either activate or suppress mental energy. If it is mainly obedience training, it suppresses energy. If it creates social dislocations, it disturbs mental and emotional energy.” -Ray Peat
“Ling discovered that cells don’t work by pumping ions with ATP. They work by structuring protein–water interactions. His experiments were flawless. But his results meant that most textbooks were wrong. That was unacceptable to the system, so instead of arguing with him, they…
Enough T3 and P4 progesterone help regenerate the thymus.
Peat always framed immune health as a metabolic issue, not an “immune system problem.” The thymus, your central immune organ for T-cell maturation, is extremely sensitive to: glucose availability magnesium availability stress hormones metabolic rate So the relationship goes…
Regulated proper levels of immune activity is the key to combat both internal and external “enemies” - not too little, not too much.
Immune vitality peaks when intracellular ions (Mg²⁺, K⁺), metabolic drivers (T3), and environmental energy (sunlight/IR) are all optimized. They form a cooperative system that maintains mitochondrial output, cellular coherence, and regulated immune activation.
Immune vitality peaks when intracellular ions (Mg²⁺, K⁺), metabolic drivers (T3), and environmental energy (sunlight/IR) are all optimized. They form a cooperative system that maintains mitochondrial output, cellular coherence, and regulated immune activation.
Peat always framed immune health as a metabolic issue, not an “immune system problem.” The thymus, your central immune organ for T-cell maturation, is extremely sensitive to: glucose availability magnesium availability stress hormones metabolic rate So the relationship goes…
If you are always stressed, you may need some teaspoons of sugar, honey and a bunch of fruits. Because short chain carbs help you to be more stress resistant. My go to: dates. They always calm me down
IF YOU'RE ALWAYS STRESSED: 1. Magnesium (evening): 200–400 mg. Start low and work up for calm and sleep support. 2. Glycine or GABA (night): simple amino support many find calming. 3. Ashwagandha (day or early evening): an adaptogen I’ve seen help stress resilience. 4.…
Light (sunlight, red, infrared, near infrared) —> all improves mitochondria efficiency in generating ATP; eventually leading to stabilizing nanoprotoplam units NPUs of Ling’s AIH theory - like T3, working with adequate magnesium Mg2+, and potassium K+ to create cellular coherence…
The new Huberman Lab episode is out: Using Red Light to Improve Metabolism & the Harmful Effects of LEDs | Dr. Glen Jeffery 0:00 Glen Jeffery 3:12 Light, Ultraviolet (UV), Visible & Infrared (IR) Light 6:25 Light's Impact on the Body & Light, Sunburn, Cataracts 9:55 UV…
Ray Peat viewed Hashimoto’s thyroiditis = low thyroid + inflammatory signals + strong stress → tissue irritation → antibody formation to clear the damaged tissue. Not the immune system attacking randomly. Not irreversible. Not fundamentally separate from hypothyroidism.…
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Ray Peat KMUD: 11-15-13 Hashimoto's, Antibodies, Temperature and...
Magnesium is also fundamental to effective vitamin D synthesis and activation.
Mg is also a cofactor for thiamine dependent enzyme transketolase and helps regulate aKGDH & PDH.
If you want to learn things about thyroid the right way, I’d suggest you look at some Ray Peat writings on thyroid on his website: Thyroid: Therapies, Confusion, and Fraud Thyroid, insomnia, and the insanities: Commonalities in disease TSH, temperature, pulse rate, and…
Do you have a list of articles and studies perhaps that you think would be good for someone getting into more formal study of thyroid function?
x.com/aihtheory/stat… Intricate relationship between T3 T4
In people without a thyroid, levothyroxine dosing must suppress TSH to achieve pre-surgical levels of thyroid hormone T3 in the blood. Many patients treated to “normalise” TSH have lower levels of thyroid hormone T3 in the blood and/or tissues. “Our study indicated that a…
Two elements critical for the stability of the NPUs in AIH theory of Ling, read these books. It will save your health. #magnesium #potassium
T3 without sufficient magnesium Mg²⁺ and potassium K+ → increases stress (adrenaline, cortisol…). Feel like hyperthyroid even though still in hypothyroidism.
Mg2+ and emphysema •Mg²⁺ → stabilizes mitochondria → decreases ROS → protects alveoli of the lung •Mg²⁺ → supports GSH → decreases oxidative damage → slow emphysema progression •Mg²⁺ → inhibits elastase → preserves elastin → decreases alveolar destruction…
Seed oil PUFA rich diet + low Mg2+ intake are the worst combo — •Low Mg²⁺ + PUFA-rich neurons → increases ferroptosis → worsens stroke outcome •Low Mg²⁺ + PUFA-rich hippocampus → increases ferroptosis → promotes Alzheimer’s pathology •Low Mg²⁺ + PUFA-rich substantia…
Exposing Seed Oils: Cancer Risks, Chemical Solvents, and the Failed Heart-Health Narrative - Chris Masterjohn on JRE m.youtube.com/watch?v=0ycNoj… Note - Peat’s Anti-PUFA Logic 1.PUFAs suppress thyroid and metabolic rate. 2.PUFAs break down into toxic lipid peroxides even at normal…
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Exposing Seed Oils: Cancer Risks, Chemical Solvents, and the Failed...
Bioenergetic keys - • Magnesium – the spark of ATP • Potassium – maintains cellular charge • Sugar (fruit > starch) – fuels mitochondria, lowers adrenaline • Red light – stimulates cytochrome oxidase • Protein (gelatin, milk, eggs) – feeds thyroid + progesterone
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