Sys4Seq, LLC
@sys4seq
Systems Biology for Sequencing #startup (Sys4Seq), #DataScience, #Bioinformatics, #NGS, #themicrobiome, #GWAS, #RareDisease, #CloudComputing
Was dir gefallen könnte
This is an outstanding study, and thread. One of the best virology manuscripts on B117.
Very excited to tell you all about our new PRE-PRINT biorxiv.org/cgi/content/sh… - Altered subgenomic RNA expression profiles in B.1.1.7 #SARSCoV2 using @nanopore & @NetworkArtic genomic seq data. This builds on our previous work describing sgRNA detection using this data 1/10
Ready to test your genetics knowledge again? Answer this week's poll question below! Approximately how many rare diseases currently exist?
“Except for polio, which is transmitted only from human to human, most of those disease agents were part of natural cycles that involved only animals. They spilled over into humans because nature was disturbed in some way. There is a lesson in that.” apple.news/AMIgHUHyaTS6iL…
Tumor-specific splicing alterations are created by mutations that disrupt splicing-regulatory elements within genes and impair splicing recognition or by altering the RNA-binding preferences of individual splicing factors. sciencedirect.com/science/articl…
Parents and caregivers of little ones, please watch. Cases of RSV are on the rise. If you see labored breathing that looks like this, contact your child’s doctor immediately. RSV can be more than a cold, and knowing the warning signs can be lifesaving.
Rectal microbes influence effectiveness of HIV vaccine medicalxpress.com/news/2019-12-r… via @medical_xpress
medicalxpress.com
Rectal microbes influence effectiveness of HIV vaccine
Microbes living in the rectum could make a difference to the effectiveness of experimental HIV vaccines, according to researchers at the University of California, Davis. The work is published Dec. 11...
Impact of Th1 CD4 TFH skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques jvi.asm.org/content/early/… #systemsvaccinology #HIV #transcriptome
Rectal Microbiome Composition Correlates with Humoral Immunity to HIV-1 in Vaccinated Rhesus Macaques msphere.asm.org/content/4/6/e0… #systemsvaccinology #HIV #microbiome
EdgeR for differential expression is included but not DESeq2!!
Bioconda, Matplotlib, Scipy, Open Refine, BWA, Qiime2 and more that are used regularly. Fantastic to have a support for #Opensource tools. A lot of good software die soon because of no support to keep them working. #OpenSource #Reproducibility
There are existing standards for the analysis of common variants in genome wide studies. However, inferring the role of rare variants in disease poses many challenges that require new approaches and standards. Excellent @NatureRevGenet review. nature.com/articles/s4157…
A small set of fast Rust scripts to convert various single cell output matrix formats [h5, csv, mtx, eds] into each other. github.com/COMBINE-lab/EDS
![k3yavi's tweet image. A small set of fast Rust scripts to convert various single cell output matrix formats [h5, csv, mtx, eds] into each other. github.com/COMBINE-lab/EDS](https://pbs.twimg.com/media/EFfrvS-XUAE4RK8.png)
MapCaller - An integrated and efficient tool for short-read mapping and variant calling using high-throughput sequenced data biorxiv.org/content/10.110… github.com/hsinnan75/MapC…
Stool sampling and DNA isolation kits affect DNA quality and bacterial composition following 16S rRNA gene sequencing using MiSeq Illumina platform - ow.ly/iHyp30pBFFq
STILL DON'T KNOW how to plan your #SingleCell transcriptome experiment? READ HERE OUR TUTORIAL: Guidelines for the experimental design of single-cell RNA sequencing studies @NatureProtocols. nature.com/articles/s4159…
A step by step explanation of Principal Component Analysis towardsdatascience.com/a-step-by-step…
Genetic variation contributes to individual differences in pleasure - Neuroscience News apple.news/AwCF54_YcNqCbq…
apple.news
Genetic variation contributes to individual differences in pleasure
Summary: What we find pleasurable may be down to our genetics. Researchers found nucleus accumbens activation and physical anhedonia were influenced by shared genes. The experience of pleasure and phy
FutureNeuro researchers integrate genomics data in to electronic patient records - SCIENMAG apple.news/AyoGUQzsGTHmms…
I am going to keep bringing up this plea as long as people keep using Tophat. This recently published paper used TopHat 1.4.1: stm.sciencemag.org/content/11/478…
Please stop using Tophat scholar.google.com.mx/scholar?hl=es&… Cole and I developed the method in *2008*. It was greatly improved in TopHat2 then HISAT & HISAT2. There is no reason to use it anymore. I have been saying this for years yet it has more citations this year than last #methodsmatter
A nice read on estimating true number of cells in scRNAseq cgatoxford.wordpress.com/2017/05/18/est… #scRNAseq
United States Trends
- 1. #WWERaw N/A
- 2. Arizona N/A
- 3. Tony Padilla N/A
- 4. Bovino N/A
- 5. Zverev N/A
- 6. Finn N/A
- 7. Brayden Burries N/A
- 8. Maple Grove N/A
- 9. El Centro N/A
- 10. Jrue N/A
- 11. #TheRookie N/A
- 12. Learner Tien N/A
- 13. Rob Wright N/A
- 14. Homan N/A
- 15. Jaden Bradley N/A
- 16. Punk N/A
- 17. Jaxson Hayes N/A
- 18. Lee Majors N/A
- 19. Highguard N/A
- 20. #RawOnNetflix N/A
Was dir gefallen könnte
-
Applied Clinical Trials
@Clin_Trials -
Garvan Institute of Medical Research
@GarvanInstitute -
Electronic Specifier
@electronicspec -
Dr. Paweł Buczkowicz
@pbuczkowicz -
Daniel Gerlach
@gerlach_d -
10x Genomics
@10xGenomics -
Yoav Gilad
@Y_Gilad -
Aedin Culhane (@[email protected])
@AedinCulhane -
InSyBio
@InSyBio -
Nathan A. Pennell MD, PhD, FASCO
@n8pennell
Something went wrong.
Something went wrong.