#hypoxia search results
🏆 Travel Grant Award – #WolfsbergMeeting 2025 How can targeting #hypoxia improve #headandneckcancer treatment? An award-winning poster shows how novel compounds can overcome hypoxia-driven #radioresistance. 👉 shorturl.at/nY0WL #RadiationBiology #Radiotherapy #HNSCC
New study from @mcgillu: #hypoxia prevents #differentiation of human trophoblast #stemcells & genes negatively regulated by low oxygen are often positively regulated by the transcription factor GCM1. #placenta #cytotrophoblast bit.ly/3GnBCX0 @ISSCR @CellPressNews
Robles-Oteíza, @Tcellogic, Politi @YaleCancer and colleagues identify #hypoxia as a key feature of immune checkpoint inhibitor-resistant tumors and demonstrate that therapeutically targeting tumor hypoxia can delay acquired resistance. hubs.la/Q02ZlHjd0 #Immunotherapy
Neuroanatomical and pharmaco-physiological effects of hypoxia and esketamine on breathing, the sympathetic nerve system, and cortical function. New editorial by Suleiman et al #hypoxia #esketamine #autonomic bjanaesthesia.org/article/S0007-…
Postdoctoral position in Bioinformatics and Data Science @TheSantoroLab Seeking a post-doc fellow to work on omics data analyses, and drug discoveries @TheSantoro Lab. jobrxiv.org/job/university… #cancer_biology #Hypoxia #mrna_translation #ScienceJobs #job
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Yongkang Yang, Gregg Semenza et al. show that, in response to intratumoral #hypoxia, #BreastCancer cells co-opt an antiviral mechanism to promote #cancer #StemCell specification and immune evasion, which are essential properties that enable #metastasis. hubs.la/Q03X_GWp0
New work by Robles-Oteíza, @Tcellogic, Politi @YaleCancer et al. provides a rationale for targeting tumor metabolic features, such as #hypoxia, in combination with immune checkpoint inhibition. hubs.la/Q02ZlHmT0 #SolidTumors #TumorImmunology #Metabolism #Immunotherapy
#Hypoxia is linked to acquired resistance to immune checkpoint inhibitors in #LungCancer, say Camila Robles-Oteíza, Susan Kaech @Tcellogic, Katerina Politi @YaleCancer and colleagues: hubs.la/Q02Zln9r0 #SolidTumors #TumorImmunology #Metabolism #Immunotherapy
Insights: Chen @UChicagoPME discusses compelling evidence by Robles-Oteiza et al. (hubs.ly/Q02ZmFNl0) linking tumor #hypoxia to acquired resistance mechanisms in non-small cell #LungCancer treatments involving immune checkpoint inhibitors (ICIs). hubs.ly/Q02ZmbPB0
#Hypoxia-activated fluorescent probes as markers of oxygen levels in plant cells and tissues Monica Perri, et al. 📖 nph.onlinelibrary.wiley.com/doi/10.1111/np…
Research Article by @AlexT_Friend et al. (@SamOliverPhD @SportSciMac) Regional dynamic #cerebral autoregulation in acute #poikilocapnic #hypoxia ow.ly/m15650WTuaL
New study from Chen et al. identifies #hypoxia-inducible protein 2 (HIG2) as a key regulator of anti-inflammatory property of Ly6ChighLy6Glow monocyte-derived #macrophages in the ischemic brain after #stroke through mediating phosphatidylcholine synthesis. hubs.la/Q047kYb30
Robles-Oteíza, Kaech, Politi et al. provide a rationale for targeting tumor metabolic features, such as #hypoxia, in combination with immune checkpoint inhibition. hubs.ly/Q03j2G8W0 📘 In JEM #Cancer Collection hubs.ly/Q03j2J8y0 #AACR25
Breathing down resistance: Tackling #hypoxia to overcome #immunotherapy barriers in #LungCancer. Huanhuan Joyce Chen @UChicagoPME highlights work from Robles-Oteiza, @Tcellogic, Politi et al. (hubs.la/Q02ZlRRb0) in Insights: hubs.la/Q02Zlnns0
Methods and Resources from S Farha et al. (@ClevelandClinic @univmiami @4DMedicalXV) Quantification of the pulmonary vasculature in mice under chronic #hypoxia with contrast-free #pulmonary #angiography in vivo imaging 🐁🫁 🔗ow.ly/hALs50UZsGm
Vascular Tone of pressurized🐭distal MCA (sham & #IschemicStroke)⏫by BKCa inhibitor Iberiotoxin Brain Arterial #EndothelialCell BKca & TRPV4 (immunofluorescence)⏫by acute (0.5~2 h) #Hypoxia or #Stroke across🐁🐀🐖🚶♂️ #SmoothMuscleCell BKCa reacts more variable Is this
Research Article by AA Jones and @GManBreathe (@UFBreathe) #Diurnalcycle and acute intermittent #hypoxia protocol interact to regulate #ventilatory long-term facilitation in unanesthetized rats ow.ly/HBIi50XTZUZ
Robles-Oteíza, @Tcellogic, Politi et al. provide a rationale for targeting tumor metabolic features, such as #hypoxia, in combination with immune checkpoint inhibition. hubs.la/Q03bvQ6t0 📘 In Tumor #Metabolism 2025: hubs.la/Q03bvVlk0 #KSTumorMetab25
This #JournalClub by Favian Morales (@UMNKinesiology) examines how #exercise and #hypoxia differentially influence platelet activation of brain-derived neurotrophic factor and platelet factor 4 based on the study by Thomas et al. (2025) ✍️ 🔗 buff.ly/LPB0i8t
تعرفوا معنا على أعراض #نقص_الأكسجين في الدم والمخ والرئة وأهمية التشخيص المبكر #dailymedicalinfo #hypoxia dailymedicalinfo.com/view-article/%…
Hypoxia | Cerebral Palsy | CP Child | Special Child #hypoxictraining #hypoxia #Hypoxiatreatment #cpchild #cerebralpalsy #cpchildtreatment #cerebralpalsytreatment #nawalsir #neurotherapy
Simerdeep K. Dhillon and colleagues at @FMHS_UoA investigated alpha-adrenergic mediated changes in blood pressure variability after #hypoxia-ischaemia in preterm #fetal sheep in this recent study 🫀 📈 Read the #Research: 🔗 buff.ly/WG9VZpw
Researchers identified a HIF regulatory network tracking #DiabeticKidneyDisease progression, with SGLT2 inhibition reversing #Hypoxia-driven transcriptional changes, highlighting it as a #Biomarker of disease & therapeutic response. #STTT #OpenAccess: doi.org/10.1038/s41392…
🆕 In this spinal fusion animal model, #hypoxia preconditioned adipose-derived stem cells (ADSCs) created larger fusion masses than untreated ADSCs. 🔗 Learn more from @JohnsHopkins researchers: bit.ly/4u5ZTVc
Interesting insights into the dynamic nature of #hypoxia on T cells and its implications for #immunotherapy! The temporal aspect could be crucial in designing treatments that are more effective. How might these findings influence current immunotherapy strategies, and are there
Low oxygen #hypoxia in tumors affects T cells differently over time: short-term hypoxia weakens their ability to kill cancer cells, but longer exposure can partially restore their function & reduce dysfunction. Timing matters for immunotherapy response. #AACR26 @yalepathology
Research Article by N Vermaerke et al. (@DebevecTadej @Chiel_Poffe @RubenRBRS @MyrtheStalmans @DomenTominec) Exogenous #ketosis mitigates #hypoxia-induced #neuralsignaling alterations and #cerebraloxygenation decline at rest in healthy males ow.ly/h4Yl50YFNVc
Mr. Heroin nonsense.... After 14 years of heroin use, you aren't just 'getting high'—you are physically shrinked your brain. #BrainAtrophy #Hypoxia #WhiteMatterDamage
Systematic review and analysis of data reported in studies regarding reduction of the cerebrovascular response to #hypoxia in conditions of pharmacological or genetic blockade of specific signaling mechanisms.
On the mechanisms of brain blood flow regulation during hypoxia. A systematic review and analysis of data reported in studies of the cerebrovascular response to hypoxia. #aerospacehumanfactors #hypoxia #adenosine physoc.onlinelibrary.wiley.com/doi/10.1113/JP…
This @PNAS study highlights the intricate interplay between #hypoxia and antiviral immunity and offers valuable insights into #pneumovirus–host interactions and potential therapeutic interventions. @UniofOxford 🧪 go.nature.com/4dQu8ui
Every chronic organ disease involves local hypoxia. That's where HIF becomes a fibrosis driver. HIF-1α/2α directly induce VEGF, CTGF, PAI-1, LOXL2, COL1A1 — and form positive feedback with TGF-β and YAP/TAZ. 🔗 fibrosis-inflammation.com/en/insights/pa… #HIF #Hypoxia #Fibrosis #CKD
慢性臓器障害は必ず局所低酸素を伴う。そのときHIFは適応応答か、線維化の駆動因子か？ HIF-1α/2αはVEGF・CTGF・PAI-1・LOXL2・COL1A1を一気に誘導。TGF-β/YAPとの正フィードバックで線維化ループを形成。 Roxadustat（HIF-PHI）の二面性も解説👇 🔗 fibrosis-inflammation.com/ja/insights/pa… #HIF #Hypoxia #CKD
PLAC8 as a potential therapeutic target for myocardial infarction: unraveling the molecular mechanisms link.springer.com/article/10.100… @NCUniv1921 #Myocardial_infarction #PLAC8 #Hypoxia #Apoptosis #MEK_ERK
HIF-1α = your cell's oxygen sensor NORMAL O₂: HIF-1α hydroxylated → degraded LOW O₂: HIF-1α stabilized → nucleus → activates survival genes Triggers: ✓ VEGF (angiogenesis) ✓ GLUT1 (glucose metabolism) ✓ EPO (red blood cells) #Science #Hypoxia #Aging
🧠The latest work from @UniBasel_en by first author Sunsha Chamakalayil and his team is now featured in AP! 👉: imrpress.com/journal/AP/27/… 💡Do #Hypoxia incidents from #Opioids impact #Neurocognition in #OpioidAgonistTreatment? #OpioidCrisis #Addiction #MentalHealth #PublicHealth
True. The Paraglider had #Hypotherma, frost bites & luckily survived. #Hypoxia as prolonged hypoxia can damage brain fuctions irreversibily.
I heard he popped his visor during his first EVA to "see what space smelled like..." He's never been the same since. #hypoxia
See what these @UCSF authors have learned about #hypoxia in this #ArticleinPress, Enhanced hypoxia resistance distinguishes human pluripotent stem cell-derived #islets from primary islets (Hiroyuki Kato et al.): ow.ly/56OV50YFATk
#5G TOWERS GOT US ALL WITH #HYPOXIA ATTACKS AT THE CLIMAX OF THE #PLANDEMIC. BEAMFORMING GRID TEST PHASE. I WAS AN OSP/HFC-FIBER TELECOMM ENGINEER AT THE TIME. "#PRECISIONTHERAPY" GIVES OUR OVERLORD CONTROL FREAKS MORE LEVERAGE FOR UNRESTRICTED I/O BIO-CYBER INTERFACING. BREATHE.
Dual-Targeted Type-I-Photosensitizer-Incorporated Covalent Organic Frameworks Overcome Hypoxia Barriers in Hepatocellular Carcinoma for Precision Therapy doi.org/10.1002/agt2.7…
What if low oxygen changes how glioma therapies behave? In C6 cells, amitriptyline reduced viability and PD-L1, but with temozolomide + radiation the response was more complex. HypoxyLab helped by holding cultures at 2.5% O2. #Hypoxia #CancerResearch spandidos-publications.com/10.3892/mco.20…
#Cardiovascular physiology and pathophysiology at high altitude : @NatRevCardiol 👉 Implications of exposure to #hypoxia for patients with cardiovascular disease: rdcu.be/dnFRf #CardioTwitter #cardiology #CardioEd
🔴 The Circadian Clock and #Hypoxia ahajrnls.org/43gUZZf #2024Review #openaccess @CircRes 👉 #Circadian Mechanisms in #Cardiovascular and #Cerebrovascular Disease! ahajournals.org/doi/10.1161/CI… #cardiology #CardioEd #CardioTwitter #MedEd #medtwitter #medical
Robles-Oteíza, @Tcellogic, Politi @YaleCancer and colleagues identify #hypoxia as a key feature of immune checkpoint inhibitor-resistant tumors and demonstrate that therapeutically targeting tumor hypoxia can delay acquired resistance. hubs.la/Q02ZlHjd0 #Immunotherapy
#Hypoxia is linked to acquired resistance to immune checkpoint inhibitors in #LungCancer, say Camila Robles-Oteíza, Susan Kaech @Tcellogic, Katerina Politi @YaleCancer and colleagues: hubs.la/Q02Zln9r0 #SolidTumors #TumorImmunology #Metabolism #Immunotherapy
Insights: Chen @UChicagoPME discusses compelling evidence by Robles-Oteiza et al. (hubs.ly/Q02ZmFNl0) linking tumor #hypoxia to acquired resistance mechanisms in non-small cell #LungCancer treatments involving immune checkpoint inhibitors (ICIs). hubs.ly/Q02ZmbPB0
Yongkang Yang, Gregg Semenza et al. show that, in response to intratumoral #hypoxia, #BreastCancer cells co-opt an antiviral mechanism to promote #cancer #StemCell specification and immune evasion, which are essential properties that enable #metastasis. hubs.la/Q03X_GWp0
New work by Robles-Oteíza, @Tcellogic, Politi @YaleCancer et al. provides a rationale for targeting tumor metabolic features, such as #hypoxia, in combination with immune checkpoint inhibition. hubs.la/Q02ZlHmT0 #SolidTumors #TumorImmunology #Metabolism #Immunotherapy
New study from Chen et al. identifies #hypoxia-inducible protein 2 (HIG2) as a key regulator of anti-inflammatory property of Ly6ChighLy6Glow monocyte-derived #macrophages in the ischemic brain after #stroke through mediating phosphatidylcholine synthesis. hubs.la/Q047kYb30
The pt below is not fromm#blueberries but this little guy is not cyanotic! What has the #patient got with blue lips and #hypoxia?
Patient’s SPO2 is 80% despite no lung pathology and clear airway What do you suspect? What’s the antidote ?
Vascular Tone of pressurized🐭distal MCA (sham & #IschemicStroke)⏫by BKCa inhibitor Iberiotoxin Brain Arterial #EndothelialCell BKca & TRPV4 (immunofluorescence)⏫by acute (0.5~2 h) #Hypoxia or #Stroke across🐁🐀🐖🚶♂️ #SmoothMuscleCell BKCa reacts more variable Is this
Neuroanatomical and pharmaco-physiological effects of hypoxia and esketamine on breathing, the sympathetic nerve system, and cortical function. New editorial by Suleiman et al #hypoxia #esketamine #autonomic bjanaesthesia.org/article/S0007-…
Research Article by J Zhao et al. (@UTAustin @Fwojan) Short bouts of #hypoxia improve #insulin sensitivity in adults with #type2diabetes 🔒ow.ly/QoM250Vl1f2
.@Dr_Dioxide14 et al @Warfellab identify a new role for PIM1 as a critical regulator of #actin dynamics & #hypoxia-induced cell #migration. hubs.la/Q02ry-9l0 From our #Cancer Cell Biology collection: hubs.la/Q02rz3h_0 #AACR2024
Fascinating research from the labs of @BangorUni being published in today's #ArticleinPress piece, Regional dynamic cerebral autoregulation in acute poikilocapnic #hypoxia (Alexander Thomas Friend et al.): ow.ly/mggH50WPHSu
Robles-Oteíza, Kaech, Politi et al. provide a rationale for targeting tumor metabolic features, such as #hypoxia, in combination with immune checkpoint inhibition. hubs.ly/Q03j2G8W0 📘 In JEM #Cancer Collection hubs.ly/Q03j2J8y0 #AACR25
🚨CALL FOR PAPERS🚨 For our "Integrative human physiology in hypoxia" #SpecialIssue, which will bring together cutting-edge studies that examine the mechanisms of #hypoxia adaptation and the consequences of chronic or intermittent #oxygen deprivation. 🔗 buff.ly/zRlzczi
Robles-Oteíza, @Tcellogic, Politi et al. provide a rationale for targeting tumor metabolic features, such as #hypoxia, in combination with immune checkpoint inhibition. hubs.la/Q03bvQ6t0 📘 In Tumor #Metabolism 2025: hubs.la/Q03bvVlk0 #KSTumorMetab25
Check out the latest work from @IUCPQ in today's #ArticleinPress: #Estrogen Receptor Alpha Determines Sex-Specific Cardiorespiratory and Autonomic Responses to Intermittent #Hypoxia in Mice (Ella Aka et al.): ow.ly/7u2x50Ycste
Hiking and climbing enthusiasts should take a good look at today's #ThrowbackThursday, Effects of two carbonic anhydrase inhibitors on #exercise performance in acute #hypoxia (Jou-Chung Chang et al. @UWaterlooKHS): ow.ly/OiyB50XHA56
Our July issue is online! Want to learn more about future directions of #hypoxia research? Then read the Opinion (featured on the cover) from @srochaliv and colleagues. Find the whole issue here 👉 cell.com/trends/biochem…
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