#spatialtranscriptomics نتائج البحث
#SpatialOmics #ImagingMassSpec #SpatialTranscriptomics MISTy Multiview Intercellular SpaTial modeling framework bioconductor.org/packages/relea… View/spatial scale-specific feature interactions Intraview - same location (intra-to-multicellulat) Juxtaview - immediate neighborhood…
#SpatialTranscriptomics 🐭#Stroke #Visium @10xGenomics #Photothrombosis 3 dpi Stroke▶️ ⏫Microglia/Macrophage Galectin-1/3/9➡️ Astrocyte/Oligodendrocyte CD44 at peri-infarct zone▶️ ⏫remyelination ⏫neurobehavioral performance Post-stroke benefits of LGALS9-expressing…
Comparing single-cell #SpatialTranscriptomics methods on FFPE human tumor #TissueMicroArray CosMx 1k vs MERFISH 500 vs Xenium-UM/-MM 339 93 common genes lung adenocarcinoma pleural mesothelioma Corr. Bulk RNAseq, GeoMx "better F1-scores with Xenium-MM (median, > 75%) than…
#WernerSyndrome hiPSC-derived engineered vessel #SpatialTranscriptomics #Visium @10xGenomics + #Metabolomics▶️ #BranchedChainKetoAcid⬇️ #MonohydroxyFattyAcid⬆️ in Werner vessels with traits of #PrematureAging Aligned #SmoothMuscleCell in Collagen hydrogel➡️ Roll-up around φ…
Accurate cell segmentation is integral to #spatialtranscriptomics—that's why we never stop improving ours. Large cells? Tissues with dense nuclei? We’ve got you covered. See how you can segment cells more accurately than ever before: bit.ly/4m1nEcz
#SpatialTranscriptomics #BrainOrganoid #Glioblastoma Striatal implant of Brain organoids +Mutant TERT p.C228T TP53 R248Q➡️SOX11+ Proneural GBM subtype +Mutant TERT p.C228T PTENΔ NF1Δ➡️ERBB3+ Mesenchymal GBM subtype In-depth single-cell spatial transcriptional & CNV landscape…
⚡️Exciting Breakthrough in Progressive Multiple Sclerosis⚡️ Much humbled to contribute to this exciting project from @Pluchinolab . Analysing 200+ sections from 50+ patients, showcases the power of #spatialtranscriptomics in rare cell localization. 🧠 @IBT_CAS @LukasValihrach
Proud to see our work out in @NeuroCellPress ! cell.com/neuron/fulltex… With Bongsoo Park, Dimitris Tsitsipatis @DanielZucha @LukasValihrach @irina_mohorianu @Pluchinolab @BeermanHSCaging !
🚨 Exciting Opportunity! 🚨 @OhioStatePIIO + @OSUWexMed Pathology are recruiting a Tenure-Track Faculty in Spatial Immuno-Oncology Research 🧬🔬 Lead cutting-edge work in #SpatialTranscriptomics, #SpatialProteomics & #ImmunoOncology to decode the #TumorMicroenvironment.…
Sequencing-free whole-genome spatial transcriptomics at single-molecule resolution. #SpatialTranscriptomics #SingleMolecule @CellCellPress cell.com/cell/fulltext/…
How do we uncover cell-cell interactions from #SpatialTranscriptomics data? Excited to share Niche-DE (doi.org/10.1186/s13059…). Niche-DE asks how does a cell’s transcriptome depend on its spatial neighbors, by identifying Niche-Differentially Expressed genes. 1/9
"We all love the pretty pictures we get from #SpatialTranscriptomics but the real value lies in the ability to precisely determine the cellular composition & cell-cell relationships - not possible with bulk RNA or even scRNA approaches" 💯% well said @bayraktar_lab! 👏 #FoG2025
Thrilled 🎉 to shared I received my R01 NoA today @NIH_NIAMS! We will continue pushing the frontiers of autoimmune research by developing novel #AI #MachineLearning for #SpatialTranscriptomics and #SingleCell modalities 🧬💻💊! @CUAnschutz @CUDeptMedicine @CUBiomedInfo
#SpatialTranscriptomics Visium #CerebralMalaria 🐭+P.berghei ANKA -/+Artesunate Malaria infection▶️ ⏫🧠#EndothelialCell, immune cells SPATA spatial trajectory inference of EC-rich spots in infected🧠▶️ ⏫EC antigen processing/presentation + leukocyte adhesion ⏬BBB Partially…
A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types. #LongReads #SingleCell #Spatialtranscriptomics #IsoSeq #PolyA @NatureComms nature.com/articles/s4146…
Ruochen Dong, @linheng_li lab, gave an outstanding presentation on using #SpatialTranscriptomics to interrogate HSC-niche interaction in the mouse fetal liver at #ISSCR2023. He also received merit and travel awards. Congratulations! @ISSCR
Systematic benchmarking of computational methods to identify spatially variable genes. #SpatialTranscriptomics #MethodsBenchmarking @GenomeBiology genomebiology.biomedcentral.com/articles/10.11…
GOD IS GOOD! Today, I passed my #PhD Dissertation Defense!!! 🎉 Thank you to everyone who believed in me. Thank you to all my mentors, friends, and family. 🥰 I would not be where I am today without all of you. 🙏❤️ @SBS_UNTHSC #SpatialTranscriptomics #DoubleDocs @A_P_S_A
#SpatialOmics #ImagingMassSpec #SpatialTranscriptomics MISTy Multiview Intercellular SpaTial modeling framework bioconductor.org/packages/relea… View/spatial scale-specific feature interactions Intraview - same location (intra-to-multicellulat) Juxtaview - immediate neighborhood…
⚡️Exciting Breakthrough in Progressive Multiple Sclerosis⚡️ Much humbled to contribute to this exciting project from @Pluchinolab . Analysing 200+ sections from 50+ patients, showcases the power of #spatialtranscriptomics in rare cell localization. 🧠 @IBT_CAS @LukasValihrach
Proud to see our work out in @NeuroCellPress ! cell.com/neuron/fulltex… With Bongsoo Park, Dimitris Tsitsipatis @DanielZucha @LukasValihrach @irina_mohorianu @Pluchinolab @BeermanHSCaging !
ChatGPT-Like AI Model Details 1,300 Regions/Subregions in Mouse Brain Map Tissue-agnostic CellTransformer can be used on other organs and tissues, including cancerous tissue, for which large-scale #spatialtranscriptomics data is available @UCSF #brain #AI hubs.li/Q03MQQXq0
🚀 Pilot Now Open: @ST_Omics OMNI with @SA_genomics & Decode Science Perfect for generating pilot data, exploring new projects, and strengthening grant applications. 🔗 Learn more: app-ap1.hubspotdocuments.com/documents/2389… #SpatialTranscriptomics #SingleCell #Genomics #EnablingDiscovery
Now Open! STOmics OMNI pilot - SAGC, @Decode_Science - spatial RNA from FFPE—end-to-end service. Why STOmics OMNI? ✅ Species-agnostic ✅ Random hexamers (total RNA) ✅ 10×10 mm area at high res (500 nm) ✅ End-to-end workflow Get your projects ready→ap1.hubs.ly/y0hZyD0
Accurate cell segmentation is integral to #spatialtranscriptomics—that's why we never stop improving ours. Large cells? Tissues with dense nuclei? We’ve got you covered. See how you can segment cells more accurately than ever before: bit.ly/4m1nEcz
🚨New #SpatialTranscriptomics #Bioinformatics data resource out in @naturemethods. SODB, a platform with >2,400 manually curated spatial experiments from >25 spatial omics technologies & interactive analytical modules. This🧵will walk you through all the features of SODB [1/33]
![simocristea's tweet image. 🚨New #SpatialTranscriptomics #Bioinformatics data resource out in @naturemethods.
SODB, a platform with >2,400 manually curated spatial experiments from >25 spatial omics technologies & interactive analytical modules.
This🧵will walk you through all the features of SODB [1/33]](https://pbs.twimg.com/media/FpqfK6HaUAAQZAo.jpg)
Comparing single-cell #SpatialTranscriptomics methods on FFPE human tumor #TissueMicroArray CosMx 1k vs MERFISH 500 vs Xenium-UM/-MM 339 93 common genes lung adenocarcinoma pleural mesothelioma Corr. Bulk RNAseq, GeoMx "better F1-scores with Xenium-MM (median, > 75%) than…
#SpatialTranscriptomics 🐭#Stroke #Visium @10xGenomics #Photothrombosis 3 dpi Stroke▶️ ⏫Microglia/Macrophage Galectin-1/3/9➡️ Astrocyte/Oligodendrocyte CD44 at peri-infarct zone▶️ ⏫remyelination ⏫neurobehavioral performance Post-stroke benefits of LGALS9-expressing…
Ruochen Dong, @linheng_li lab, gave an outstanding presentation on using #SpatialTranscriptomics to interrogate HSC-niche interaction in the mouse fetal liver at #ISSCR2023. He also received merit and travel awards. Congratulations! @ISSCR
How do we uncover cell-cell interactions from #SpatialTranscriptomics data? Excited to share Niche-DE (doi.org/10.1186/s13059…). Niche-DE asks how does a cell’s transcriptome depend on its spatial neighbors, by identifying Niche-Differentially Expressed genes. 1/9
We’re all wondering what the future of #spatialtranscriptomics (ST) has in store. Well, I think the near future will look a lot like the new 6000-plex dataset reviewed here (link to the original source at the end of this post). SAMPLE An entire 100 mm² intact 5 µm FFPE section…
#SpatialTranscriptomics #BrainOrganoid #Glioblastoma Striatal implant of Brain organoids +Mutant TERT p.C228T TP53 R248Q➡️SOX11+ Proneural GBM subtype +Mutant TERT p.C228T PTENΔ NF1Δ➡️ERBB3+ Mesenchymal GBM subtype In-depth single-cell spatial transcriptional & CNV landscape…
A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types. #LongReads #SingleCell #Spatialtranscriptomics #IsoSeq #PolyA @NatureComms nature.com/articles/s4146…
#WernerSyndrome hiPSC-derived engineered vessel #SpatialTranscriptomics #Visium @10xGenomics + #Metabolomics▶️ #BranchedChainKetoAcid⬇️ #MonohydroxyFattyAcid⬆️ in Werner vessels with traits of #PrematureAging Aligned #SmoothMuscleCell in Collagen hydrogel➡️ Roll-up around φ…
🚨 Exciting Opportunity! 🚨 @OhioStatePIIO + @OSUWexMed Pathology are recruiting a Tenure-Track Faculty in Spatial Immuno-Oncology Research 🧬🔬 Lead cutting-edge work in #SpatialTranscriptomics, #SpatialProteomics & #ImmunoOncology to decode the #TumorMicroenvironment.…
Excited to share our #SingleCell and #SpatialTranscriptomics analysis of #ExerciseTraining remodeling of #WhiteAdiposeTissue through innervation, vascularization, and #ExtracellularMatrix in mouse and human with #LaurieGoodyear #JanWillemMiddelbeek @PasqualeNigro9 @MVamvini…
Excellent talk from @Sandy_Figiel in @Uroweb #EAUlab session at #EAU25 presenting our cool data (I'm bias!) on #SpatialTranscriptomics & #ClonalAnalysis to detect unique features of metastasing clones in #ProstateCancer. @OxPCaBiol #SPACE_Study #3DLightsheet
"We all love the pretty pictures we get from #SpatialTranscriptomics but the real value lies in the ability to precisely determine the cellular composition & cell-cell relationships - not possible with bulk RNA or even scRNA approaches" 💯% well said @bayraktar_lab! 👏 #FoG2025
We are very very VERY excited to be running #cosmx #singlecell #spatialtranscriptomics experiments in @UofGlasgow @UofGCancerSci @UofGMVLS Well done to the @LabSpatialNBJ team @nanostringtech
High-resolution mapping of single cells in spatial context. #SingleCell #SpatialTranscriptomics #Bioinformatics @NatureComms nature.com/articles/s4146…
#SpatialTranscriptomics Visium #CerebralMalaria 🐭+P.berghei ANKA -/+Artesunate Malaria infection▶️ ⏫🧠#EndothelialCell, immune cells SPATA spatial trajectory inference of EC-rich spots in infected🧠▶️ ⏫EC antigen processing/presentation + leukocyte adhesion ⏬BBB Partially…
Pleased to share our latest #SpatialTranscriptomics output now on @biorxivpreprint We show marked variation in gene expr relating to @Decipher_VCYT, #Oncotype_DX & #ProstaDiag genomic scores Being presented by @Sandy_Figiel this afternoon #EAU23!! biorxiv.org/content/10.110…
STOmicsDB #SpatialTranscriptomics repository Coding-free visualization & re-analysis of published ST datasets (if you have a specific question) 361 datasets 128 tissues 17 species db.cngb.org/stomics/ #NucAcidRes 2023 academic.oup.com/nar/article/52…
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