#spatialtranscriptomics hasil pencarian

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Tidak ada hasil untuk "#spatialtranscriptomics"
Tidak ada hasil untuk "#spatialtranscriptomics"

Systematic comparisons among 4 subcellular-resolution #SpatialTranscriptomics methods Stereo-seq v1.3 Visium HD FFPE CosMx 6k Xenium 5k Human Tumors Ground truth CODEX, +scRNAseq Gene detection sensitivity (CosMx performance...🙁) (Spatial) false positives Transcript-protein…

HaoYin20's tweet image. Systematic comparisons among 4 subcellular-resolution #SpatialTranscriptomics methods

Stereo-seq v1.3
Visium HD FFPE
CosMx 6k
Xenium 5k

Human Tumors
Ground truth CODEX, +scRNAseq

Gene detection sensitivity (CosMx performance...🙁)
(Spatial) false positives
Transcript-protein…

Comparative analysis of commercial Imaging-based #SpatialTranscriptomics methods Xenium CosMx 1k MERSCOPE Tissue Microarray 17 tumors + 16 normal tissues Transcript count Corr. with reference bulk TCGA GTEx RNAseq or scRNAseq Segmentation (Precision Recall F1 score) Accuracy:…

HaoYin20's tweet image. Comparative analysis of commercial Imaging-based #SpatialTranscriptomics methods

Xenium
CosMx 1k
MERSCOPE

Tissue Microarray
17 tumors + 16 normal tissues

Transcript count
Corr. with reference bulk TCGA GTEx RNAseq or scRNAseq
Segmentation (Precision Recall F1 score) Accuracy:…

🚨New #SpatialTranscriptomics #Bioinformatics data resource out in @naturemethods. SODB, a platform with >2,400 manually curated spatial experiments from >25 spatial omics technologies & interactive analytical modules. This🧵will walk you through all the features of SODB [1/33]

simocristea's tweet image. 🚨New #SpatialTranscriptomics #Bioinformatics data resource out in @naturemethods.

SODB, a platform with >2,400 manually curated spatial experiments from >25 spatial omics technologies & interactive analytical modules.

This🧵will walk you through all the features of SODB [1/33]

Ruochen Dong, @linheng_li lab, gave an outstanding presentation on using #SpatialTranscriptomics to interrogate HSC-niche interaction in the mouse fetal liver at #ISSCR2023. He also received merit and travel awards. Congratulations! @ISSCR

ScienceStowers's tweet image. Ruochen Dong, @linheng_li lab, gave an outstanding presentation on using #SpatialTranscriptomics to interrogate HSC-niche interaction in the mouse fetal liver at #ISSCR2023. He also received merit and travel awards. Congratulations! @ISSCR

#SpatialTranscriptomics STcompare github.com/JEFworks-Lab/S… Test your gene of interest if it is differentially spatially patterned (r, p, s)🤠 Spatial correlation Spatial fold change Control for spatial autocorrelation Comparisons will be straightforward with Alignment (STalign)…

HaoYin20's tweet image. #SpatialTranscriptomics

STcompare
github.com/JEFworks-Lab/S…

Test your gene of interest if it is differentially spatially patterned (r, p, s)🤠
Spatial correlation
Spatial fold change
Control for spatial autocorrelation

Comparisons will be straightforward with Alignment (STalign)…

We’re all wondering what the future of #spatialtranscriptomics (ST) has in store. Well, I think the near future will look a lot like the new 6000-plex dataset reviewed here (link to the original source at the end of this post). SAMPLE An entire 100 mm² intact 5 µm FFPE section…

BrantBassamPhD's tweet image. We’re all wondering what the future of #spatialtranscriptomics (ST) has in store. Well, I think the near future will look a lot like the new 6000-plex  dataset reviewed here (link to the original source at the end of this post).

SAMPLE
An entire 100 mm² intact 5 µm FFPE section…
BrantBassamPhD's tweet image. We’re all wondering what the future of #spatialtranscriptomics (ST) has in store. Well, I think the near future will look a lot like the new 6000-plex  dataset reviewed here (link to the original source at the end of this post).

SAMPLE
An entire 100 mm² intact 5 µm FFPE section…
BrantBassamPhD's tweet image. We’re all wondering what the future of #spatialtranscriptomics (ST) has in store. Well, I think the near future will look a lot like the new 6000-plex  dataset reviewed here (link to the original source at the end of this post).

SAMPLE
An entire 100 mm² intact 5 µm FFPE section…
BrantBassamPhD's tweet image. We’re all wondering what the future of #spatialtranscriptomics (ST) has in store. Well, I think the near future will look a lot like the new 6000-plex  dataset reviewed here (link to the original source at the end of this post).

SAMPLE
An entire 100 mm² intact 5 µm FFPE section…

#SpatialTranscriptomics Visium @10xGenomics Human Left Atrial Appendage (n=2 donors) & Pulmonary Vein (n=8 donors) Spatial location of #AtrialFibrillation risk genes PITX2 SHOX2 HCN4 @CVpathol 2025 sciencedirect.com/science/articl…

HaoYin20's tweet image. #SpatialTranscriptomics 
Visium @10xGenomics

Human Left Atrial Appendage (n=2 donors) & Pulmonary Vein (n=8 donors)

Spatial location of #AtrialFibrillation risk genes PITX2 SHOX2 HCN4

@CVpathol 2025
sciencedirect.com/science/articl…

Excited to share our #SingleCell and #SpatialTranscriptomics analysis of #ExerciseTraining remodeling of #WhiteAdiposeTissue through innervation, vascularization, and #ExtracellularMatrix in mouse and human with #LaurieGoodyear #JanWillemMiddelbeek @PasqualeNigro9 @MVamvini

manoliskellis's tweet image. Excited to share our #SingleCell and #SpatialTranscriptomics analysis of #ExerciseTraining remodeling of #WhiteAdiposeTissue through innervation, vascularization, and #ExtracellularMatrix in mouse and human with #LaurieGoodyear #JanWillemMiddelbeek @PasqualeNigro9 @MVamvini…
manoliskellis's tweet image. Excited to share our #SingleCell and #SpatialTranscriptomics analysis of #ExerciseTraining remodeling of #WhiteAdiposeTissue through innervation, vascularization, and #ExtracellularMatrix in mouse and human with #LaurieGoodyear #JanWillemMiddelbeek @PasqualeNigro9 @MVamvini…
manoliskellis's tweet image. Excited to share our #SingleCell and #SpatialTranscriptomics analysis of #ExerciseTraining remodeling of #WhiteAdiposeTissue through innervation, vascularization, and #ExtracellularMatrix in mouse and human with #LaurieGoodyear #JanWillemMiddelbeek @PasqualeNigro9 @MVamvini…
manoliskellis's tweet image. Excited to share our #SingleCell and #SpatialTranscriptomics analysis of #ExerciseTraining remodeling of #WhiteAdiposeTissue through innervation, vascularization, and #ExtracellularMatrix in mouse and human with #LaurieGoodyear #JanWillemMiddelbeek @PasqualeNigro9 @MVamvini…

CoCo-ST detects global and local biological structures in spatial transcriptomics datasets. #SpatialTranscriptomics #VarianceIdentification @NatureCellBio nature.com/articles/s4155…

jsantoyo's tweet image. CoCo-ST detects global and local biological structures in spatial transcriptomics datasets. #SpatialTranscriptomics #VarianceIdentification @NatureCellBio 
nature.com/articles/s4155…

We are very very VERY excited to be running #cosmx #singlecell #spatialtranscriptomics experiments in @UofGlasgow @UofGCancerSci @UofGMVLS Well done to the @LabSpatialNBJ team @nanostringtech

LabSpatialNBJ's tweet image. We are very very VERY excited to be running #cosmx #singlecell #spatialtranscriptomics experiments in @UofGlasgow @UofGCancerSci @UofGMVLS 

Well done to the @LabSpatialNBJ team 

@nanostringtech
LabSpatialNBJ's tweet image. We are very very VERY excited to be running #cosmx #singlecell #spatialtranscriptomics experiments in @UofGlasgow @UofGCancerSci @UofGMVLS 

Well done to the @LabSpatialNBJ team 

@nanostringtech

Comparing single-cell #SpatialTranscriptomics methods on FFPE human tumor #TissueMicroArray CosMx 1k vs MERFISH 500 vs Xenium-UM/-MM 339 93 common genes lung adenocarcinoma pleural mesothelioma Corr. Bulk RNAseq, GeoMx "better F1-scores with Xenium-MM (median, > 75%) than…

HaoYin20's tweet image. Comparing single-cell #SpatialTranscriptomics methods on FFPE human tumor #TissueMicroArray

CosMx 1k vs MERFISH 500 vs Xenium-UM/-MM 339
93 common genes

lung adenocarcinoma
pleural mesothelioma

Corr. Bulk RNAseq, GeoMx

"better F1-scores with Xenium-MM (median, > 75%) than…

Excellent talk from @Sandy_Figiel in @Uroweb #EAUlab session at #EAU25 presenting our cool data (I'm bias!) on #SpatialTranscriptomics & #ClonalAnalysis to detect unique features of metastasing clones in #ProstateCancer. @OxPCaBiol #SPACE_Study #3DLightsheet

LambAlastair's tweet image. Excellent talk from @Sandy_Figiel in @Uroweb #EAUlab session at #EAU25 presenting our cool data (I'm bias!) on #SpatialTranscriptomics & #ClonalAnalysis to detect unique features of metastasing clones in #ProstateCancer. 

@OxPCaBiol #SPACE_Study #3DLightsheet
LambAlastair's tweet image. Excellent talk from @Sandy_Figiel in @Uroweb #EAUlab session at #EAU25 presenting our cool data (I'm bias!) on #SpatialTranscriptomics & #ClonalAnalysis to detect unique features of metastasing clones in #ProstateCancer. 

@OxPCaBiol #SPACE_Study #3DLightsheet
LambAlastair's tweet image. Excellent talk from @Sandy_Figiel in @Uroweb #EAUlab session at #EAU25 presenting our cool data (I'm bias!) on #SpatialTranscriptomics & #ClonalAnalysis to detect unique features of metastasing clones in #ProstateCancer. 

@OxPCaBiol #SPACE_Study #3DLightsheet
LambAlastair's tweet image. Excellent talk from @Sandy_Figiel in @Uroweb #EAUlab session at #EAU25 presenting our cool data (I'm bias!) on #SpatialTranscriptomics & #ClonalAnalysis to detect unique features of metastasing clones in #ProstateCancer. 

@OxPCaBiol #SPACE_Study #3DLightsheet

🔬 A new computational approach pioneered by researchers at the @broadinstitute eliminates time-intensive imaging, enabling high-resolution spatial mapping of gene expression in tissue. See how they're making #SpatialTranscriptomics easier for everyone: bit.ly/3G9Hrau

ScienceinBoston's tweet image. 🔬 A new computational approach pioneered by researchers at the @broadinstitute eliminates time-intensive imaging, enabling high-resolution spatial mapping of gene expression in tissue.

See how they're making #SpatialTranscriptomics easier for everyone: bit.ly/3G9Hrau

Diabetic #T2D db/db 🐭 heart-coronary resistance microvessel multiomics FFPE-scRNAseq #SpatialTranscriptomics Visium @10xGenomics Proteomics Septal Coronary resistance microvessels (how to isolate?😮) Traits of Fatty acid β-oxidation & ketogenesis (Hmgcs2, Acot2) in diabetic…

HaoYin20's tweet image. Diabetic #T2D db/db 🐭 heart-coronary resistance microvessel multiomics

FFPE-scRNAseq
#SpatialTranscriptomics Visium @10xGenomics
Proteomics Septal Coronary resistance microvessels (how to isolate?😮) 

Traits of Fatty acid β-oxidation & ketogenesis (Hmgcs2, Acot2) in diabetic…

STORIES SpatioTemporal Omics eneRgIES Learning Waddington epigenetic (+regulon) landscape from multi-time-point Stereo-seq #SpatialTranscriptomics Potential-based Fused Gromov-Wasserstein #OptimalTransport Linear▶️gene expression error Quadratic▶️spatial consistency @gjhuizing

HaoYin20's tweet image. STORIES
SpatioTemporal Omics eneRgIES

Learning Waddington epigenetic (+regulon) landscape from multi-time-point Stereo-seq #SpatialTranscriptomics

Potential-based
Fused Gromov-Wasserstein #OptimalTransport
Linear▶️gene expression error
Quadratic▶️spatial consistency

@gjhuizing…

Pleased to share our latest #SpatialTranscriptomics output now on @biorxivpreprint We show marked variation in gene expr relating to @Decipher_VCYT, #Oncotype_DX & #ProstaDiag genomic scores Being presented by @Sandy_Figiel this afternoon #EAU23!! biorxiv.org/content/10.110…

LambAlastair's tweet image. Pleased to share our latest #SpatialTranscriptomics output now on @biorxivpreprint

We show marked variation in gene expr relating to @Decipher_VCYT, #Oncotype_DX & #ProstaDiag genomic scores

Being presented by @Sandy_Figiel this afternoon #EAU23!!

biorxiv.org/content/10.110…
LambAlastair's tweet image. Pleased to share our latest #SpatialTranscriptomics output now on @biorxivpreprint

We show marked variation in gene expr relating to @Decipher_VCYT, #Oncotype_DX & #ProstaDiag genomic scores

Being presented by @Sandy_Figiel this afternoon #EAU23!!

biorxiv.org/content/10.110…
LambAlastair's tweet image. Pleased to share our latest #SpatialTranscriptomics output now on @biorxivpreprint

We show marked variation in gene expr relating to @Decipher_VCYT, #Oncotype_DX & #ProstaDiag genomic scores

Being presented by @Sandy_Figiel this afternoon #EAU23!!

biorxiv.org/content/10.110…
LambAlastair's tweet image. Pleased to share our latest #SpatialTranscriptomics output now on @biorxivpreprint

We show marked variation in gene expr relating to @Decipher_VCYT, #Oncotype_DX & #ProstaDiag genomic scores

Being presented by @Sandy_Figiel this afternoon #EAU23!!

biorxiv.org/content/10.110…

"We all love the pretty pictures we get from #SpatialTranscriptomics but the real value lies in the ability to precisely determine the cellular composition & cell-cell relationships - not possible with bulk RNA or even scRNA approaches" 💯% well said @bayraktar_lab! 👏 #FoG2025

LambAlastair's tweet image. "We all love the pretty pictures we get from #SpatialTranscriptomics but the real value lies in the ability to precisely determine the cellular composition & cell-cell relationships - not possible with bulk RNA or even scRNA approaches"

💯% well said @bayraktar_lab!
👏
#FoG2025
LambAlastair's tweet image. "We all love the pretty pictures we get from #SpatialTranscriptomics but the real value lies in the ability to precisely determine the cellular composition & cell-cell relationships - not possible with bulk RNA or even scRNA approaches"

💯% well said @bayraktar_lab!
👏
#FoG2025
LambAlastair's tweet image. "We all love the pretty pictures we get from #SpatialTranscriptomics but the real value lies in the ability to precisely determine the cellular composition & cell-cell relationships - not possible with bulk RNA or even scRNA approaches"

💯% well said @bayraktar_lab!
👏
#FoG2025
LambAlastair's tweet image. "We all love the pretty pictures we get from #SpatialTranscriptomics but the real value lies in the ability to precisely determine the cellular composition & cell-cell relationships - not possible with bulk RNA or even scRNA approaches"

💯% well said @bayraktar_lab!
👏
#FoG2025

Congrats to @Sandy_Figiel for winning poster 1st Prize (out of 53 posters!) at #OxSymp23 @OxfordCancer. Using #SpatialTranscriptomics to reveal problem of heterogeneity when using genomic prognostic scores in #ProstateCancer #Organscale Full preprint: biorxiv.org/content/10.110…

LambAlastair's tweet image. Congrats to @Sandy_Figiel for winning poster 1st Prize (out of 53 posters!) at #OxSymp23 @OxfordCancer.

Using #SpatialTranscriptomics to reveal problem of heterogeneity when using genomic prognostic scores in #ProstateCancer
#Organscale

Full preprint:
biorxiv.org/content/10.110…
LambAlastair's tweet image. Congrats to @Sandy_Figiel for winning poster 1st Prize (out of 53 posters!) at #OxSymp23 @OxfordCancer.

Using #SpatialTranscriptomics to reveal problem of heterogeneity when using genomic prognostic scores in #ProstateCancer
#Organscale

Full preprint:
biorxiv.org/content/10.110…
LambAlastair's tweet image. Congrats to @Sandy_Figiel for winning poster 1st Prize (out of 53 posters!) at #OxSymp23 @OxfordCancer.

Using #SpatialTranscriptomics to reveal problem of heterogeneity when using genomic prognostic scores in #ProstateCancer
#Organscale

Full preprint:
biorxiv.org/content/10.110…
LambAlastair's tweet image. Congrats to @Sandy_Figiel for winning poster 1st Prize (out of 53 posters!) at #OxSymp23 @OxfordCancer.

Using #SpatialTranscriptomics to reveal problem of heterogeneity when using genomic prognostic scores in #ProstateCancer
#Organscale

Full preprint:
biorxiv.org/content/10.110…

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