#spatialtranscriptomics результаты поиска

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Systematic comparisons among 4 subcellular-resolution #SpatialTranscriptomics methods Stereo-seq v1.3 Visium HD FFPE CosMx 6k Xenium 5k Human Tumors Ground truth CODEX, +scRNAseq Gene detection sensitivity (CosMx performance...🙁) (Spatial) false positives Transcript-protein…

HaoYin20's tweet image. Systematic comparisons among 4 subcellular-resolution #SpatialTranscriptomics methods

Stereo-seq v1.3
Visium HD FFPE
CosMx 6k
Xenium 5k

Human Tumors
Ground truth CODEX, +scRNAseq

Gene detection sensitivity (CosMx performance...🙁)
(Spatial) false positives
Transcript-protein…

🚨New #SpatialTranscriptomics #Bioinformatics data resource out in @naturemethods. SODB, a platform with >2,400 manually curated spatial experiments from >25 spatial omics technologies & interactive analytical modules. This🧵will walk you through all the features of SODB [1/33]

simocristea's tweet image. 🚨New #SpatialTranscriptomics #Bioinformatics data resource out in @naturemethods.

SODB, a platform with >2,400 manually curated spatial experiments from >25 spatial omics technologies & interactive analytical modules.

This🧵will walk you through all the features of SODB [1/33]

Ruochen Dong, @linheng_li lab, gave an outstanding presentation on using #SpatialTranscriptomics to interrogate HSC-niche interaction in the mouse fetal liver at #ISSCR2023. He also received merit and travel awards. Congratulations! @ISSCR

ScienceStowers's tweet image. Ruochen Dong, @linheng_li lab, gave an outstanding presentation on using #SpatialTranscriptomics to interrogate HSC-niche interaction in the mouse fetal liver at #ISSCR2023. He also received merit and travel awards. Congratulations! @ISSCR

Comparing single-cell #SpatialTranscriptomics methods on FFPE human tumor #TissueMicroArray CosMx 1k vs MERFISH 500 vs Xenium-UM/-MM 339 93 common genes lung adenocarcinoma pleural mesothelioma Corr. Bulk RNAseq, GeoMx "better F1-scores with Xenium-MM (median, > 75%) than…

HaoYin20's tweet image. Comparing single-cell #SpatialTranscriptomics methods on FFPE human tumor #TissueMicroArray

CosMx 1k vs MERFISH 500 vs Xenium-UM/-MM 339
93 common genes

lung adenocarcinoma
pleural mesothelioma

Corr. Bulk RNAseq, GeoMx

"better F1-scores with Xenium-MM (median, > 75%) than…

CoCo-ST detects global and local biological structures in spatial transcriptomics datasets. #SpatialTranscriptomics #VarianceIdentification @NatureCellBio nature.com/articles/s4155…

jsantoyo's tweet image. CoCo-ST detects global and local biological structures in spatial transcriptomics datasets. #SpatialTranscriptomics #VarianceIdentification @NatureCellBio 
nature.com/articles/s4155…

#WernerSyndrome hiPSC-derived engineered vessel #SpatialTranscriptomics #Visium @10xGenomics + #Metabolomics▶️ #BranchedChainKetoAcid⬇️ #MonohydroxyFattyAcid⬆️ in Werner vessels with traits of #PrematureAging Aligned #SmoothMuscleCell in Collagen hydrogel➡️ Roll-up around φ…

HaoYin20's tweet image. #WernerSyndrome
hiPSC-derived engineered vessel

#SpatialTranscriptomics #Visium @10xGenomics + #Metabolomics▶️
#BranchedChainKetoAcid⬇️
 #MonohydroxyFattyAcid⬆️
in Werner vessels with traits of #PrematureAging

Aligned #SmoothMuscleCell in Collagen hydrogel➡️
Roll-up around φ…

🔬 A new computational approach pioneered by researchers at the @broadinstitute eliminates time-intensive imaging, enabling high-resolution spatial mapping of gene expression in tissue. See how they're making #SpatialTranscriptomics easier for everyone: bit.ly/3G9Hrau

ScienceinBoston's tweet image. 🔬 A new computational approach pioneered by researchers at the @broadinstitute eliminates time-intensive imaging, enabling high-resolution spatial mapping of gene expression in tissue.

See how they're making #SpatialTranscriptomics easier for everyone: bit.ly/3G9Hrau

Excellent talk from @Sandy_Figiel in @Uroweb #EAUlab session at #EAU25 presenting our cool data (I'm bias!) on #SpatialTranscriptomics & #ClonalAnalysis to detect unique features of metastasing clones in #ProstateCancer. @OxPCaBiol #SPACE_Study #3DLightsheet

LambAlastair's tweet image. Excellent talk from @Sandy_Figiel in @Uroweb #EAUlab session at #EAU25 presenting our cool data (I'm bias!) on #SpatialTranscriptomics & #ClonalAnalysis to detect unique features of metastasing clones in #ProstateCancer. 

@OxPCaBiol #SPACE_Study #3DLightsheet
LambAlastair's tweet image. Excellent talk from @Sandy_Figiel in @Uroweb #EAUlab session at #EAU25 presenting our cool data (I'm bias!) on #SpatialTranscriptomics & #ClonalAnalysis to detect unique features of metastasing clones in #ProstateCancer. 

@OxPCaBiol #SPACE_Study #3DLightsheet
LambAlastair's tweet image. Excellent talk from @Sandy_Figiel in @Uroweb #EAUlab session at #EAU25 presenting our cool data (I'm bias!) on #SpatialTranscriptomics & #ClonalAnalysis to detect unique features of metastasing clones in #ProstateCancer. 

@OxPCaBiol #SPACE_Study #3DLightsheet
LambAlastair's tweet image. Excellent talk from @Sandy_Figiel in @Uroweb #EAUlab session at #EAU25 presenting our cool data (I'm bias!) on #SpatialTranscriptomics & #ClonalAnalysis to detect unique features of metastasing clones in #ProstateCancer. 

@OxPCaBiol #SPACE_Study #3DLightsheet

Spider: a flexible and unified framework for simulating spatial transcriptomics data. #SpatialTranscriptomics #DataSimulation #Genomics #Bioinformatics 🧬 🖥️ academic.oup.com/bioinformatics…

jsantoyo's tweet image. Spider: a flexible and unified framework for simulating spatial transcriptomics data. #SpatialTranscriptomics #DataSimulation #Genomics #Bioinformatics 🧬 🖥️ 
academic.oup.com/bioinformatics…

#SpatialTranscriptomics #ParkinsonsDisease A role of #FGF9 in Glia #Ferroptosis in PD?😁 #Visium @10xGenomics +snRNAseq MPTP🐭 #SubstantiaNigra FGF9 ⏬in PD Neuron ⏫in PD Ependymal cell FGF9-to-FGFR1/2/3 (CellChat, likely Neuron-to-Oligodendrocyte/Astrocyte) ⏬in PD…

HaoYin20's tweet image. #SpatialTranscriptomics #ParkinsonsDisease

A role of #FGF9 in Glia #Ferroptosis in PD?😁

#Visium @10xGenomics
+snRNAseq
MPTP🐭 #SubstantiaNigra

FGF9 ⏬in PD Neuron ⏫in PD Ependymal cell

FGF9-to-FGFR1/2/3 (CellChat, likely Neuron-to-Oligodendrocyte/Astrocyte) ⏬in PD…

We’re all wondering what the future of #spatialtranscriptomics (ST) has in store. Well, I think the near future will look a lot like the new 6000-plex dataset reviewed here (link to the original source at the end of this post). SAMPLE An entire 100 mm² intact 5 µm FFPE section…

BrantBassamPhD's tweet image. We’re all wondering what the future of #spatialtranscriptomics (ST) has in store. Well, I think the near future will look a lot like the new 6000-plex  dataset reviewed here (link to the original source at the end of this post).

SAMPLE
An entire 100 mm² intact 5 µm FFPE section…
BrantBassamPhD's tweet image. We’re all wondering what the future of #spatialtranscriptomics (ST) has in store. Well, I think the near future will look a lot like the new 6000-plex  dataset reviewed here (link to the original source at the end of this post).

SAMPLE
An entire 100 mm² intact 5 µm FFPE section…
BrantBassamPhD's tweet image. We’re all wondering what the future of #spatialtranscriptomics (ST) has in store. Well, I think the near future will look a lot like the new 6000-plex  dataset reviewed here (link to the original source at the end of this post).

SAMPLE
An entire 100 mm² intact 5 µm FFPE section…
BrantBassamPhD's tweet image. We’re all wondering what the future of #spatialtranscriptomics (ST) has in store. Well, I think the near future will look a lot like the new 6000-plex  dataset reviewed here (link to the original source at the end of this post).

SAMPLE
An entire 100 mm² intact 5 µm FFPE section…

STORIES SpatioTemporal Omics eneRgIES Learning Waddington epigenetic (+regulon) landscape from multi-time-point Stereo-seq #SpatialTranscriptomics Potential-based Fused Gromov-Wasserstein #OptimalTransport Linear▶️gene expression error Quadratic▶️spatial consistency @gjhuizing

HaoYin20's tweet image. STORIES
SpatioTemporal Omics eneRgIES

Learning Waddington epigenetic (+regulon) landscape from multi-time-point Stereo-seq #SpatialTranscriptomics

Potential-based
Fused Gromov-Wasserstein #OptimalTransport
Linear▶️gene expression error
Quadratic▶️spatial consistency

@gjhuizing…

Pleased to share our latest #SpatialTranscriptomics output now on @biorxivpreprint We show marked variation in gene expr relating to @Decipher_VCYT, #Oncotype_DX & #ProstaDiag genomic scores Being presented by @Sandy_Figiel this afternoon #EAU23!! biorxiv.org/content/10.110…

LambAlastair's tweet image. Pleased to share our latest #SpatialTranscriptomics output now on @biorxivpreprint

We show marked variation in gene expr relating to @Decipher_VCYT, #Oncotype_DX & #ProstaDiag genomic scores

Being presented by @Sandy_Figiel this afternoon #EAU23!!

biorxiv.org/content/10.110…
LambAlastair's tweet image. Pleased to share our latest #SpatialTranscriptomics output now on @biorxivpreprint

We show marked variation in gene expr relating to @Decipher_VCYT, #Oncotype_DX & #ProstaDiag genomic scores

Being presented by @Sandy_Figiel this afternoon #EAU23!!

biorxiv.org/content/10.110…
LambAlastair's tweet image. Pleased to share our latest #SpatialTranscriptomics output now on @biorxivpreprint

We show marked variation in gene expr relating to @Decipher_VCYT, #Oncotype_DX & #ProstaDiag genomic scores

Being presented by @Sandy_Figiel this afternoon #EAU23!!

biorxiv.org/content/10.110…
LambAlastair's tweet image. Pleased to share our latest #SpatialTranscriptomics output now on @biorxivpreprint

We show marked variation in gene expr relating to @Decipher_VCYT, #Oncotype_DX & #ProstaDiag genomic scores

Being presented by @Sandy_Figiel this afternoon #EAU23!!

biorxiv.org/content/10.110…

In our latest study, we look at how storing kidneys on ice before transplant can cause damage over time. We use #spatialtranscriptomics to characterize cold ischemia injury at multiple time points to reveal compartment-specific changes Preprint: biorxiv.org/content/10.110… 🧵👇 1/n

JEFworks's tweet image. In our latest study, we look at how storing kidneys on ice before transplant can cause damage over time. We use #spatialtranscriptomics to characterize cold ischemia injury at multiple time points to reveal compartment-specific changes

Preprint: biorxiv.org/content/10.110…

🧵👇 1/n

"We all love the pretty pictures we get from #SpatialTranscriptomics but the real value lies in the ability to precisely determine the cellular composition & cell-cell relationships - not possible with bulk RNA or even scRNA approaches" 💯% well said @bayraktar_lab! 👏 #FoG2025

LambAlastair's tweet image. "We all love the pretty pictures we get from #SpatialTranscriptomics but the real value lies in the ability to precisely determine the cellular composition & cell-cell relationships - not possible with bulk RNA or even scRNA approaches"

💯% well said @bayraktar_lab!
👏
#FoG2025
LambAlastair's tweet image. "We all love the pretty pictures we get from #SpatialTranscriptomics but the real value lies in the ability to precisely determine the cellular composition & cell-cell relationships - not possible with bulk RNA or even scRNA approaches"

💯% well said @bayraktar_lab!
👏
#FoG2025
LambAlastair's tweet image. "We all love the pretty pictures we get from #SpatialTranscriptomics but the real value lies in the ability to precisely determine the cellular composition & cell-cell relationships - not possible with bulk RNA or even scRNA approaches"

💯% well said @bayraktar_lab!
👏
#FoG2025
LambAlastair's tweet image. "We all love the pretty pictures we get from #SpatialTranscriptomics but the real value lies in the ability to precisely determine the cellular composition & cell-cell relationships - not possible with bulk RNA or even scRNA approaches"

💯% well said @bayraktar_lab!
👏
#FoG2025

1st single-cell #SpatialTranscriptomics map of human coronary #Atherosclerosis published in peer-reviewed format🤠 CosMx 1k + GeoMx @brukerspatial Immune cell-focused analysis Use CosMx data to deconvolve GeoMx cell composition...😆 @EmboMolMed 2025 embopress.org/doi/full/10.10…

HaoYin20's tweet image. 1st single-cell #SpatialTranscriptomics map of human coronary #Atherosclerosis published in peer-reviewed format🤠

CosMx 1k + GeoMx @brukerspatial

Immune cell-focused analysis

Use CosMx data to deconvolve GeoMx cell composition...😆

@EmboMolMed 2025
embopress.org/doi/full/10.10…

Congrats to @Sandy_Figiel for winning poster 1st Prize (out of 53 posters!) at #OxSymp23 @OxfordCancer. Using #SpatialTranscriptomics to reveal problem of heterogeneity when using genomic prognostic scores in #ProstateCancer #Organscale Full preprint: biorxiv.org/content/10.110…

LambAlastair's tweet image. Congrats to @Sandy_Figiel for winning poster 1st Prize (out of 53 posters!) at #OxSymp23 @OxfordCancer.

Using #SpatialTranscriptomics to reveal problem of heterogeneity when using genomic prognostic scores in #ProstateCancer
#Organscale

Full preprint:
biorxiv.org/content/10.110…
LambAlastair's tweet image. Congrats to @Sandy_Figiel for winning poster 1st Prize (out of 53 posters!) at #OxSymp23 @OxfordCancer.

Using #SpatialTranscriptomics to reveal problem of heterogeneity when using genomic prognostic scores in #ProstateCancer
#Organscale

Full preprint:
biorxiv.org/content/10.110…
LambAlastair's tweet image. Congrats to @Sandy_Figiel for winning poster 1st Prize (out of 53 posters!) at #OxSymp23 @OxfordCancer.

Using #SpatialTranscriptomics to reveal problem of heterogeneity when using genomic prognostic scores in #ProstateCancer
#Organscale

Full preprint:
biorxiv.org/content/10.110…
LambAlastair's tweet image. Congrats to @Sandy_Figiel for winning poster 1st Prize (out of 53 posters!) at #OxSymp23 @OxfordCancer.

Using #SpatialTranscriptomics to reveal problem of heterogeneity when using genomic prognostic scores in #ProstateCancer
#Organscale

Full preprint:
biorxiv.org/content/10.110…

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