#microenvironment search results
New #hematopoiesis research from @UWMadison: GABA produced by multiple bone marrow cell types regulate hematopoietic stem and progenitor cells. #microenvironment #bonemarrow #Bcells ow.ly/b0OE50XeaPE @ISSCR @CellPressNews @GairdnerAwards @SickKidsNews
IL-9 secreted by leukemia stem cells induces Th1-skewed CD4+ T cells, which promote their expansion doi.org/10.1182/blood.… #leusm @BloodJournal #microenvironment
A new study explores the connection between #microenvironment, survival, and immune escape in #DLBCL treated with #R-CHOP. haematologica.org/article/view/h…
Mesenchymal stromal cells from JAK2V617F myeloproliferative neoplasms support healthy and malignant hematopoiesis in a humanized scaffold model in vivo doi.org/10.1002/hem3.7… #MPNsm #MDSsm #microenvironment @Hemasphere_EHA @KordastiL @harrisoncn1 @TheCrick @MPN_Hub @MDS_Hub
Thanking all our #Cancer #Signaling & #Microenvironment Program members, for a terrific and fun retreat!! @FoxChaseCancer @templemedschool foxchase.org/research-train…
Researchers at @umcg with Dr.@MoerkensRenee used organ-on-chip technology to develop a #hiPSC-derived intestinal barrier 🚧 with apical and basolateral access in a more physiological #microenvironment. 📖 @CellReports | bit.ly/3RRSQ1r?
Just published— Akiyama et al. show that stromal targeting with PDGFRα/β dual blockade reverses the immunosuppressive #microenvironment and enhances the efficacy of immune checkpoint inhibitors in fibrotic cancer. bit.ly/3mBSZJW @kumamotoUniv_PR
👇 Cancer #organoids 2.0! The authors discuss currently available and rapidly evolving 3D tumor 🧫 organoid models that capture important #immune features of the tumor immune #microenvironment. @NatureRevCancer | 🔗 go.nature.com/3xOEAQu
From MBoC @tamal_das is excited to share latest findings on how matrix stiffness affects mitochondria! Study reveals perinuclear clustering on stiff matrix & its importance in priming stem cells towards osteogenesis. #microenvironment #mitochondria doi.org/10.1091/mbc.E2…
Calling all immunologists interested in the influence of the stroma & #microenvironment on #ImmuneResponses! Today is your last chance to submit an abstract for @BSI_Midlands' symposium #BSIMidlands24 🤩 Submit yours by 23:59 BST TONIGHT (15 May) 👉bit.ly/3uw2fDm
⛱️Don't miss our August Issue🧴 🎯Focus on the TME, the immune system and cell metabolism interaction, in relation to various therapeutic approaches utilised for the treatment of cancer 🏊♀️Dive in 🔓buff.ly/3SHud85 #ImmunoOnc #Microenvironment #OncoImmunology
There’s a surge of interest in #microclimate & #microenvironment + how they shape #vegetation & #PlantEcology🌿My 1999 PhD work tackled this - how fine-scale variation in canopy dynamics, topography etc drives palm ecology in tropical #forests - see: researchgate.net/publication/22…🌴🌤️🌴
☑️ Take a deep dive into #cancer tissue analysis with Leica Microsystems Cell DIVE in this on-demand webinar. Learn how the hyperplex workflow can help reveal new insights into the #tumor #microenvironment. ☑️ Register to watch 👉 fcld.ly/su8njr4 #MultiplexImagingMonday
Dimitris Lagos received a Cancer Immunology Project Award to explore #microenvironment response to transcriptome instability in renal cancer and instability markers for immunotherapy response. @UniOfYork | #CRUKFunded
Starting in Bérgamo 🇮🇹 the @EACRnews congress on "The Tumour Ecosystem" with the opening keynote lecture by Prof. Douglas Hanahan. #tumor #microenvironment #tme #oncology #Immunology
[5/8] Simon Robinson received a Programme Award to advance MRI biomarkers (multiparametric, oxygen-enhanced & magnetic resonance elastography) to assess the tumour #microenvironment and enhance tumour detection & treatment response. #CRUKFunded @ICR_London
![CRUKresearch's tweet image. [5/8]
Simon Robinson received a Programme Award to advance MRI biomarkers (multiparametric, oxygen-enhanced & magnetic resonance elastography) to assess the tumour #microenvironment and enhance tumour detection & treatment response.
#CRUKFunded
@ICR_London](https://pbs.twimg.com/media/GlNgVQiXsAEjTwx.jpg)
The 2nd talk in the #tumour #microenvironment session is by Andrew White @Cornell who is talking about monocyte-derived macrophages and their influence on acquired therapy resistance @MelanomaReAlli #melanoma
Our final highlight from the May issue of Cell comes from a duo at @AlbanyMed. Roles for epithelial integrin α3β1 in regulation of the #microenvironment during normal and #pathological tissue remodeling (Rakshitha Miskin and Michael DiPersio): ow.ly/bnfj50RYFYm
💬 The collaborative actions of CXCL9 and SPP1 were found to collectively dictate the polarity of tumor-associated #macrophages within the tumor #microenvironment, exerting profound effects on #tumor progression and 💊 treatment responses. 🔗 bit.ly/3SndffK
📢NEW #SpecialIssue ON "#Radiotherapy and the Tumor #Microenvironment: From Basic Mechanisms to Clinical Translation" 👨⚕️Guest Editors: Dr. Eleanor J. Cheadle and Dr. Jamie Honeychurch @OfficialUoM ➡Look forward to receiving your submission at: mdpi.com/journal/cancer…
New #hematopoiesis research from @UWMadison: GABA produced by multiple bone marrow cell types regulate hematopoietic stem and progenitor cells. #microenvironment #bonemarrow #Bcells ow.ly/b0OE50XeaPE @ISSCR @CellPressNews @GairdnerAwards @SickKidsNews
👍This paper reviews how the complex #tumor #microenvironment drives #cholangiocarcinoma initiation, progression, and therapeutic resistance, providing insights for novel targeted and immunotherapeutic strategies. @MariaEva_Argenz @michelemontori1 @MarcoMarzioni74 @Aiims1742
🧫 The Role of Tumor Microenvironment in #Cholangiocarcinoma Crosstalk between stromal & immune cells Microenvironment-driven tumor evolution Opportunities for precision immunotherapy 🔗 [oaepublish.com/articles/2394-…] #BileDuctCancer #TumorMicroenvironment #Immunotherapy
![HepatomaRes's tweet image. 🧫 The Role of Tumor Microenvironment in #Cholangiocarcinoma
Crosstalk between stromal & immune cells
Microenvironment-driven tumor evolution
Opportunities for precision immunotherapy
🔗 [oaepublish.com/articles/2394-…]
#BileDuctCancer #TumorMicroenvironment #Immunotherapy](https://pbs.twimg.com/media/G36Iy_NX0AAhvE1.png)
![HepatomaRes's tweet image. 🧫 The Role of Tumor Microenvironment in #Cholangiocarcinoma
Crosstalk between stromal & immune cells
Microenvironment-driven tumor evolution
Opportunities for precision immunotherapy
🔗 [oaepublish.com/articles/2394-…]
#BileDuctCancer #TumorMicroenvironment #Immunotherapy](https://pbs.twimg.com/media/G36I2EwWoAAPOjW.jpg)
![HepatomaRes's tweet image. 🧫 The Role of Tumor Microenvironment in #Cholangiocarcinoma
Crosstalk between stromal & immune cells
Microenvironment-driven tumor evolution
Opportunities for precision immunotherapy
🔗 [oaepublish.com/articles/2394-…]
#BileDuctCancer #TumorMicroenvironment #Immunotherapy](https://pbs.twimg.com/media/G36I4BBXkAAGByH.jpg)
🌟Welcome to Talk about the spatiotemporal remodeling of the tumor immune microenvironment (TIME) and the cellular and molecular mechanisms underlying immune evasion. Know it: oaepublish.com/specials/jcmt.… #Tumor #immune #microenvironment #evasion #immunotherapy #biomarkers
@shanestecklein from @KUcancercenter shows that the radiosensitivity index (RSI) biomarker in #TNBC provides insight into the tumor immune #microenvironment, predicts response to neoadjuvant systemic therapy, and changes during the course of neoadjuvant therapy. Read about it in…
🙌Publish in #Cancer #DrugResistance about Ovarian tumor microenvironment! 👉Title: Ovarian tumor #microenvironment contributes to tumor progression and #chemoresistance 👀Read: oaepublish.com/articles/cdr.2… 📩Download: f.oaes.cc/xmlpdf/8953d47…
Increased Sirtuin 6 Activity in Tumor Cells Can Prompt CD4-Positive T-Cell Differentiation Into Regulatory T Cells and Impede Immune Surveillance in the Microenvironment wjon.elmerpub.com/wjon/article/v… #Tregs; Immune #surveillance; Tumor #microenvironment; Sirt6; ADO; PD-1/PD-L1; IFN-γ
📖 Unlocking immunity. Our new study on is now published. 🍲 The Role of #Tregs in the Tumor #Microenvironment #Immunology #Science Read it here: mdpi.com/2227-9059/13/5… @MDPIOpenAccess @MDPIBiologySubj
A new study using the 🔬 CELENA S Digital Imaging System has developed a novel 3D #hydrogel matrix that models the intestinal #immune #microenvironment. This work opens the door to further detailed in vitro studies of intestinal #immunology. 👩🔬👨🔬👍 ow.ly/smFW50WVH01
nature.com/articles/s4158… The #mechanical #microenvironment (e.g. pressure from surrounding cells and from different #ECM stiffness) induce phenotypical changes in cancer cells. Interestingly, these cells sense the pressure IN THE NUCLEUS, through a DNA-bending protein.
💡#LastestPaper 📚Variations in Circulating #Tumor #Microenvironment-Associated Proteins in Non-Muscle Invasive #Bladder #Cancer Induced by Mitomycin C Treatment 🧑🔬by Dr. Cristina Núñez, et al. 🔗Read full paper: mdpi.com/1422-0067/26/1… #cancertherapy #OpenAccess #MDPIIJMS
Mesenchymal stromal cells from JAK2V617F myeloproliferative neoplasms support healthy and malignant hematopoiesis in a humanized scaffold model in vivo doi.org/10.1002/hem3.7… #MPNsm #MDSsm #microenvironment @Hemasphere_EHA @KordastiL @harrisoncn1 @TheCrick @MPN_Hub @MDS_Hub
✨Calling for Submissions✨ 📕Gynecologic #Oncology: #Tumor #Microenvironment and Novel Therapeutics 👩🔬Guest Editor: Dr. Carmela Ricciardelli ⏰Submission Deadline: 30 November 2025 🔗More Info: mdpi.com/journal/ijms/s… #Gynecology #CancerTherapy #Cancer #callforpapers
📢#ArticleHF Particulate Matter Emissions at Different Microenvironments Using Low-Cost Sensors in Megacity Dhaka, Bangladesh Read it: mdpi.com/2073-4433/15/8… Read more papers: mdpi.com/journal/atmosp… #particulate_matter #microenvironment
What if we could predict how a tumor’s #microenvironment in the body would influence cancer progression? With spatial #transcriptomics, these breakthroughs are near: ow.ly/lgVT50WvvG3
Attend tomorrow's Assessing the #Tumor #Microenvironment with Systems #Immunology webinar about cutting-edge computational tools & analytical approaches that reveal the complexities of the TME & #tumor immunobiology! Register now for this exciting program: sitcancer.org/CompIO
🙌This study explores how #collagen expression shapes the #tumor #microenvironment, fueling growth, invasion, and therapeutic resistance. @JoeYeong @Youngthepro @retoinmuno @yekeduz_emre @ItaiYanai @VirusesImmunity @EricTopol @JaviVaquero84 @duckhuca @asharmaiisc @CarlKayMD
🧬 Collagens in intrahepatic #Cholangiocarcinoma! 🧱 Aberrant collagen deposition in iCCA 🔗 Role in tumor #progression & #metastasis 🎯 Potential as #diagnostic & #therapeutic targets 🔗 Read more: [oaepublish.com/articles/2394-…]
![HepatomaRes's tweet image. 🧬 Collagens in intrahepatic #Cholangiocarcinoma!
🧱 Aberrant collagen deposition in iCCA
🔗 Role in tumor #progression & #metastasis
🎯 Potential as #diagnostic & #therapeutic targets
🔗 Read more: [oaepublish.com/articles/2394-…]](https://pbs.twimg.com/media/GyrmpjmaoAAMouB.png)
![HepatomaRes's tweet image. 🧬 Collagens in intrahepatic #Cholangiocarcinoma!
🧱 Aberrant collagen deposition in iCCA
🔗 Role in tumor #progression & #metastasis
🎯 Potential as #diagnostic & #therapeutic targets
🔗 Read more: [oaepublish.com/articles/2394-…]](https://pbs.twimg.com/media/GyrmrU9bwAEYpDb.jpg)
![HepatomaRes's tweet image. 🧬 Collagens in intrahepatic #Cholangiocarcinoma!
🧱 Aberrant collagen deposition in iCCA
🔗 Role in tumor #progression & #metastasis
🎯 Potential as #diagnostic & #therapeutic targets
🔗 Read more: [oaepublish.com/articles/2394-…]](https://pbs.twimg.com/media/Gyrmsf7bAAAsT2V.jpg)
🧩 Decoding the fibrotic tumor #microenvironment in #cholangiocarcinoma 🧬 Key #ECM remodeling mechanisms 🪢 #Fibrosis as a tumor-promoting niche 🎯 Therapeutic opportunities in #matrix targeting 🔗 Read more: [oaepublish.com/articles/2394-…]
![HepatomaRes's tweet image. 🧩 Decoding the fibrotic tumor #microenvironment in #cholangiocarcinoma
🧬 Key #ECM remodeling mechanisms
🪢 #Fibrosis as a tumor-promoting niche
🎯 Therapeutic opportunities in #matrix targeting
🔗 Read more: [oaepublish.com/articles/2394-…]](https://pbs.twimg.com/media/GymMG4QaoAAIyWi.png)
![HepatomaRes's tweet image. 🧩 Decoding the fibrotic tumor #microenvironment in #cholangiocarcinoma
🧬 Key #ECM remodeling mechanisms
🪢 #Fibrosis as a tumor-promoting niche
🎯 Therapeutic opportunities in #matrix targeting
🔗 Read more: [oaepublish.com/articles/2394-…]](https://pbs.twimg.com/media/GymMIgRa4AA4GzC.jpg)
![HepatomaRes's tweet image. 🧩 Decoding the fibrotic tumor #microenvironment in #cholangiocarcinoma
🧬 Key #ECM remodeling mechanisms
🪢 #Fibrosis as a tumor-promoting niche
🎯 Therapeutic opportunities in #matrix targeting
🔗 Read more: [oaepublish.com/articles/2394-…]](https://pbs.twimg.com/media/GymMJdqasAA3kXj.jpg)
IL-9 secreted by leukemia stem cells induces Th1-skewed CD4+ T cells, which promote their expansion doi.org/10.1182/blood.… #leusm @BloodJournal #microenvironment
A new study explores the connection between #microenvironment, survival, and immune escape in #DLBCL treated with #R-CHOP. haematologica.org/article/view/h…
From MBoC @tamal_das is excited to share latest findings on how matrix stiffness affects mitochondria! Study reveals perinuclear clustering on stiff matrix & its importance in priming stem cells towards osteogenesis. #microenvironment #mitochondria doi.org/10.1091/mbc.E2…
Do not forget that #leukemia has also a tumor #microenvironment #TME ! Excelent session chaired by @iannisaifantis1 with Simona Colla @MDAndersonNews and Simon Mendez-Ferrer @Cambridge_Uni
Our final highlight from the May issue of Cell comes from a duo at @AlbanyMed. Roles for epithelial integrin α3β1 in regulation of the #microenvironment during normal and #pathological tissue remodeling (Rakshitha Miskin and Michael DiPersio): ow.ly/bnfj50RYFYm
Researchers at @umcg with Dr.@MoerkensRenee used organ-on-chip technology to develop a #hiPSC-derived intestinal barrier 🚧 with apical and basolateral access in a more physiological #microenvironment. 📖 @CellReports | bit.ly/3RRSQ1r?
Officially defended my PhD dissertation yesterday uncovering the #meningioma #microenvironment Super thankful to have amazing mentors on my thesis committee and in general! Esp. Drs. Gunel, Apuzzo, Claus, Krishnaswamy, Louvi & Dr Micheal Nitabach & Dr. Gunter Wagner
☑️ Take a deep dive into #cancer tissue analysis with Leica Microsystems Cell DIVE in this on-demand webinar. Learn how the hyperplex workflow can help reveal new insights into the #tumor #microenvironment. ☑️ Register to watch 👉 fcld.ly/su8njr4 #MultiplexImagingMonday
Thanking all our #Cancer #Signaling & #Microenvironment Program members, for a terrific and fun retreat!! @FoxChaseCancer @templemedschool foxchase.org/research-train…
Our #SpatialBiology summits continue in Paris at the @InstitutImagine. 🔬Lots of great science ahead with talks on #pancreatic cancer #microenvironment resolved with GeoMx DSP and anti-cancer #vaccination response unraveled by CosMx SMI. 👉bit.ly/3okkzfr
👇 Cancer #organoids 2.0! The authors discuss currently available and rapidly evolving 3D tumor 🧫 organoid models that capture important #immune features of the tumor immune #microenvironment. @NatureRevCancer | 🔗 go.nature.com/3xOEAQu
Starting in Bérgamo 🇮🇹 the @EACRnews congress on "The Tumour Ecosystem" with the opening keynote lecture by Prof. Douglas Hanahan. #tumor #microenvironment #tme #oncology #Immunology
Looking for a postdoc in #leukemia #microenvironment #bioengineering field while having fun in the beautiful city of #Paris🥐🧀🍷? Here a last chance to get in touch and join us to do some great science together 👇 register to the @ISEHSociety career fair next week #passarolab
Just published— Akiyama et al. show that stromal targeting with PDGFRα/β dual blockade reverses the immunosuppressive #microenvironment and enhances the efficacy of immune checkpoint inhibitors in fibrotic cancer. bit.ly/3mBSZJW @kumamotoUniv_PR
Excited to join a distinguished line-up of scientists at the upcoming @cshlmeetings on the tumor #microenvironment. Stroma rules!
Katrien De Bock @debocklab @ETH_en presents Metabolism in the muscle #microenvironment, next month in Lisbon. Still to time register. @CellSymposia #Exmet2024 hubs.li/Q02tC3ZR0
⚠️Abstract Deadline Alert- MONDAY Present your work on the #Tumour #microenvironment #SystemicEnvironment #TherapeuticTargeting #TherapyResistance at #TumourLandscape23 ✍️➡️ cvent.com/c/abstracts/d6… Org'd by: @MSKCancerCenter @Nature @NatureCancer @NatureRevCancer
There’s a surge of interest in #microclimate & #microenvironment + how they shape #vegetation & #PlantEcology🌿My 1999 PhD work tackled this - how fine-scale variation in canopy dynamics, topography etc drives palm ecology in tropical #forests - see: researchgate.net/publication/22…🌴🌤️🌴
Mesenchymal stromal cells from JAK2V617F myeloproliferative neoplasms support healthy and malignant hematopoiesis in a humanized scaffold model in vivo doi.org/10.1002/hem3.7… #MPNsm #MDSsm #microenvironment @Hemasphere_EHA @KordastiL @harrisoncn1 @TheCrick @MPN_Hub @MDS_Hub
Single-cell sequencing reveals the immune #microenvironment landscape related to anti-PD-1 resistance in metastatic #ColorectalCancer with high microsatellite instability, reports a team at Kunming Medical University. bit.ly/3HADrO2
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